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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Group B streptococci, a frequent cause of neonatal sepsis and meningitis, postpartum endometritis, and bovine mastitis, may be acquired by several modes of transmission. Detailed epidemiologic study is hampered by the lack of a sufficiently discriminatory typing system, especially for type III and nontypable strains. We examined 54 epidemiologically well-characterized strains by restriction endonuclease analysis (REA) and compared the results with those obtained by serotyping. REA patterns were inspected without knowledge of the epidemiological or serotyping data. Among 21 type Ia, Ia/c, and Ib/c isolates, we found 10 REA patterns; among 5 type II and IIc isolates, we found 5 REA patterns; among 13 type III isolates, we found 6 REA patterns; and among 15 nontypable human and animal isolates, we found 7 different REA patterns. Double digestion of type III isolates with EcoRI and BglII helped us to distinguish the isolates. In total, 28 REA patterns were found in six serotype groups and one nontypable group. Some geographically and epidemiologically separate isolates had identical REA patterns, suggesting dissemination of a limited number of clones. We conclude that REA is a promising tool for detailed epidemiological study of group B streptococci.
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PMID:Restriction endonuclease analysis of human and bovine group B streptococci for epidemiologic study. 266 44

The measurement of colloid-oncotic pressure (COP) in 160 women with pyoseptic disease (pyodermia, soft-tissue abscesses, suppurative mastitis, endometritis, sepsis) has demonstrated a regular pattern of change, depending on the clinical condition. A classification of COP disorders has been proposed, identifying the hyperoncotic state (COP above 3.29 kPa), normoncotic state (COP between 2.84 and 3.29 kPa) and hypo-oncotic state (COP below 2.84 kPa), on which a differential remedial therapy is based. A reliable assessment of COP values during the infusion therapy can only be made by means of oncometry, since estimations of any kind lead to considerable error.
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PMID:[Differential correction of disorders of colloid-oncotic blood pressure in pregnant women and puerperants with suppurative-septic diseases]. 273 6

Forty-six Escherichia coli isolates of serotype O2:K1 from human urinary tract infections, chicken sepsis, and bovine mastitis were obtained from laboratories in England, Denmark, Sweden, and Finland. The bacteria were compared for outer membrane protein (OMP) pattern, lipopolysaccharide pattern, electrophoretic mobilities of enzymes, and flagellar serotype and were tested for fimbriation, biotype, hydroxamate production, hemolysin production, antibiotic resistance, plasmid content, colicin production, and virulence in neonatal rats. Isolates from humans were assigned to two clonal groups; poultry isolates belonged to one of these clonal groups, whereas bovine isolates belonged to the other. Poultry and human isolates of the same clonal group could be distinguished only by their plasmid content. Strains within this group were heterogeneous with respect to biotype, fimbriation, virulence, and flagellar serotype. Human and bovine isolates of the second clonal group were distinguished by a minor change in OMP pattern and by their plasmid content. It is concluded that meaningful clonal groupings are best recognized by the combination of OMP and electrophoretic enzyme patterns. The O:K serotype can aid in the recognition of important subclones, whereas the other microbiological properties tested can vary widely within clonal groupings. Furthermore, we conclude that certain O:K serotypes can contain very different clonal groupings having little genetic relatedness.
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PMID:Clonal analysis of Escherichia coli O2:K1 isolated from diseased humans and animals. 351 Jan 71

Mycoplasma (M.) capricolum has been frequently isolated from diseased as well as from healthy sheep in Morocco. In order to determine its pathogenicity for sheep, experiments were performed in three trials with the Moroccan isolate 012. The following results were obtained: Ewes inoculated intramammarily developed acute mastitis; the organism was transmitted to lambs suckling these ewes. Only a mild mastitis appeared after a second inoculum, performed 5 weeks after the first. Young lambs, 1 month of age, fed four times with M. capricolum broth culture, died during the septicemic phase, showing a generalized septicemia, polyarthritis and a diffuse interstitial pneumonia. Lambs, 2 and 3 months of age inoculated intrabronchially developed a disease, which appeared to be age and weight dependent. The more susceptible animals died within 1-2 weeks after infection. The older lambs recovered gradually from the disease, which was characterized by pneumonia, conjunctivitis and arthritis. A significant increase of antibodies against M. capricolum developed in the older animals in the complement fixation test.
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PMID:Pathogenicity of Mycoplasma capricolum in sheep after experimental infection. 366 May 81

We reviewed the disease process in goats caused by Mycoplasma capricolum, M. mycoides subsp. mycoides, and M. putrefaciens and compared mycoplasma-infected goats (particularly young kids) for microanatomic changes. M. capricolum and M. mycoides subsp. mycoides cause a nearly identical disease: septicemia leading to pyrexia, high morbidity and mortality, interstitial pneumonia, arthritis (including polyarthritis), and mastitis. Until recently, M. putrefaciens was known only as a cause of mastitis. However, a new isolate of M. putrefaciens may be transiently septicemic, as evidenced by polyarthritis with isolations from joints, lung, brain, kidney, pleural fluid, uterus, and urine.
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PMID:Comparison of caprine mycoplasmosis caused by Mycoplasma capricolum, Mycoplasma mycoides subsp. mycoides, and Mycoplasma putrefaciens. 366 29

Characteristic features of expert evaluation of temporary disability during pregnancy and after abortion and labor adopted in the USSR are outlined. At the earliest stages of pregnancy, women should be assigned to the work not associated with potential exposure to hazardous factors. Women with pregnancy complications should undergo comprehensive examination, preferably in a hospital setting: average length of stay is 20 days for threatened abortion, 21 days for premature labor (28-37-week pregnancy), 16 days for hypertension, 14 days for vomiting or nephropathy, 17 days for anemia, and 14 days for Rhesus-incompatibility. After abortion on demand or abortion for medical indications, a woman should be given a sick leave. The length of sick leave depends upon the pregnancy term (56 days for pregnancy longer than 28 weeks). Women with normal pregnancy and labor can receive a leave for 112 calendar days (56 days during the prelabor period and 56 days for the postpartum period). In the case of labor complications or multiple pregnancy, duration of the postpartum leave should be increased to 70 days. Indications for a 70-day postpartum leave include preeclampsia or eclampsia; cesarean section or vacuum-extraction; profuse hemorrhage during labor requiring blood transfusions; tears of the cervix uteri; postpartum endometritis, thrombophlebitis, septicemia, and suppurative mastitis; history of heart valve disease or congenital heart defects; and premature labor.
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PMID:[Expert evaluation of temporary disability with regard to pregnancy, abortion and labor]. 368 64

The examination of 47 patients with acute purulent lactation mastitis and 14 patients with the resulting sepsis has shown a decreased level of nonspecific resistance factors. Generalization of the purulent process is characterized by disturbed humoral and cellular links of immunity. The dynamic research of immunity factors can give an estimation of the effectiveness of the chosen treatment and prognosis of possible complications. The general bactericidal activity of blood may be considered one of the most informative indices showing the direction of the process.
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PMID:[Importance of the indices of immunity for predicting the course and assessing the effectiveness of the treatment in acute suppurative lactation mastitis]. 383 57

Hemolytic Escherichia coli was isolated from the mammary glands of 8 ferrets with gangrenous mastitis. Clinical signs included firm swelling of one or more mammary glands and discoloration of the overlying skin. Peracute disease and acute septicemia were observed, and in some cases the animals rapidly became moribund. Antibiotic therapy alone did not alter the course of the disease. Wide surgical resection of the involved glands in combination with systemic antibiotic therapy (ampicillin 10 mg/kg, BID, and gentamicin 5 mg/kg, SID) was the most successful treatment. Histopathologic changes included extensive edema, hemorrhage, and necrosis, with a mixed leukocytic infiltrate and large numbers of bacteria. The agent of this disease was isolated from rectal swab specimens from clinically normal ferrets as well as ferrets that had mastitis.
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PMID:Mastitis caused by hemolytic Escherichia coli in the ferret. 635 64

The periodicity of morbidity rate in heifers and dairy cows kept on pasture (278 animals) and in stables (187 animals) was studied in relation to macroclimatic conditions under the assumption of two peaks per annum. The following conditions were used as the parameters of morbidity: purulent inflammations of uterus, sterility, lesions of the female tract and sepsis, dystocia, retention of placenta, mastitis, foot diseases and lying down after parturition. No significant differences were found between the studied groups of animals. A statistically significant up to highly significant dependence was found between the health of the heifers and cows and macroclimatic conditions both in stables and on pasture; an increase in morbidity rate was recorded in spring and autumn.
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PMID:[Health status of cattle in relation to the time of year]. 641 43

The antimicrobial effect of oxytocin in combination with 39 antibacterial drugs was studied in vitro with the use of 30 strains of different test cultures. It was shown that oxytocin had a capacity for potentiating the antibiotic effect on many microbial species. The potentiation ratio depended on the antibiotic and microbial species used and ranged from 2 to 24 times. The combined therapy with oxytocin and antibiotics was tested on animals with experimental staphylococcal sepsis. The survival rate of more than 50 per cent was observed only in the group of animals treated with the combinations of antibiotics and oxytocin, while in the other groups the death rate amounted to 100 per cent. The most favourable combinations of oxytocin and antibiotics were used in the treatment of 260 patients with pyoinflammatory affections of the soft tissues (mastitis, postinfection suppuration, paraproctitis, etc). In the majority of cases, the surgical treatment was replaced by the paracentetic treatment with local application of the combinations of oxytocin and antibiotics. This markedly decreased (by 3-4 times) the periods of temporary disability, provided better cosmetic results of the treatment and lowered consumption of the dressing material.
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PMID:[Potentiation of the antimicrobial action of antibiotics in combination with oxytocin]. 674 8


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