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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 1958-74 altogether 64 cases of bacteriologically verified infections of Listeria monocytogenes were diagnosed in Sweden in children, aged more than 27 days, and in adults. Immunosuppression predisposed to the disease. Thus, many patients had co-existing disorders, such as leukemia and alcoholism. Sixteen patients had been treated with corticosteroids, which were combined with cytostatic drugs in nine. Meningoencephalitis was diagnosed in 52 patients and was fatal in 16. The clinical symptoms did not differ from those in purulent meningitis caused by other bacteria. In the cerebrospinal fluid the cellular response was dominated by polymorphonuclear cells in 29 patients and by mononuclear cells in 20. Ten patients had septicemia, which was fatal in four. Clinical symptoms were dominated by chills, high fever and general prostration. One patient had pleurisy and one an abscess of the neck; both recovered. Serotypes 1 and 4b prevailed and were equally common. Many patients developed raised antibody titers in both the O-agglutination test and the complement fixation test. The titers were often not positive until after a month. Moderate granulocytosis was the rule and monocytosis was rarely seen. Ampicillin alone or combined with an aminoglycoside seemed to be the drug of choice in the treatment of listeriosis. An alternative drug was tetracycline. Most deaths occurred within six days of onset of the illness. Early diagnosis and treatment were imperative. Most patients recovered and serious sequelae were rare.
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PMID:Clinical aspects on 64 cases of juvenile and adult listeriosis in Sweden. 10 52

Three clinical pictures were found in ten cases of listeriosis after renal transplantation: septicemia (six cases), meningo-encephalitis (three cases) and asymtomatic but recurrent bacteriuria (one case). Several features demonstrate profound immunologic disturbances in the recipient: close relationship in 9 cases out of 10 between infection and high doses of immunosuppressive drugs, unfavorable outcome of graft (accelerated rejection in 4 cases out of 10) and association in one case with lethal pulmonary infection due to opportunistic agents (cytomegalovirus and Pneumocystis carinii).
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PMID:[Listeriosis in the kidney transplant recipients. Ten cases (author's transl)]. 39 56

In 1958--1974 altogether 110 cases of listeriosis were diagnosed in Sweden by culture. 64 cases were seen in children and adults. Of these, 52 had manifestations of meningoencephalitis and 10 of septicemia. Another 46 cases were seen in pregnant women and/or their neonates. Pregnancy ended in abortions in 8 cases and in stillborns in 3. Out of 37 neonates born alive, 22 had "early disease", mostly granulomatosis infantiseptica, and 8 had "late disease" with meningoencephalitis. The reported frequency of listeriosis in humans showed no correlation with that in animals. With the exception of pregnant women the incidence and mortality showed no difference with sex. Serotypes 1 and 4b prevailed and were equally common. The serotype did not vary with the clinical diagnosis or the outcome. There was no seasonal variation. Cases of all serotypes were uniformly distributed over the country in proportion to the density of its population. Occupational contact with animals was less common. Only in a few cases was there reason to suspect infection from animals. Co-existing disorders predisposed for the disease and often determined its outcome. Neonates with early onset of disease were infected by their mothers, while neonates with late onset of disease were infected from other and often nosocomial sources.
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PMID:Epidemiology of listeriosis in Sweden 1958--1974. 41 68

Clinical data were correlated with postmortem findings in 14 cases of fatal listeriosis in adults and 23 cases of listeriosis during pregnancy and the neonatal period. Most children born with congenital listeriosis showed the typical morphological picture of granulomatosis infantiseptica. Occasionally no pathological changes were demonstrable. In adult patients the morphological lesions were those of non-specific purulent meningoencephalitis or septicemia. Sometimes encephalitis with abscesses in the brain was found.
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PMID:Correlations between clinical and postmortem findings in listeriosis. 41 69

Cases of human listeriosis have recently increased in Western France (Maine-et-Loire and Mayenne); until 1974, there were only 15 documented cases yearly where as in 1975, there were 113 cases, and in 1976, 54 documented cases at the hospitals of Angers and Laval. Included amongst the clinical manifestations observed, were 126 cases of materno-fetal infections and 41 cases of either septicemia or meningo-encephalitis. The bacteriological study revealed a certain variability of biological characteristics examined, the overwhelming frequence of bacteria of the strain 4 b and the predictable sensitivity of this strain to antibiotics commonly employed in cases of listeriosis. The human cases were notably more frequent between January and June but their geographical distribution was not related to cases of either animal disease nor listeria that was isolated from corn silage. In this report, we propose an etio-pathological explanation for this epidemic.
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PMID:[Epidemic of listeriosis in Western France (1975--1976)]. 47 10

Nine cases of neonatal listeriosis observed in 1973 and 1974 are presented. Diagnosis was established during life in eight cases by positivity of bacteriological cultures. Given the high incidence of listeria sepsis and the important mortality, it is necessary to establish an early diagnosis, an immediate antibiotic therapy and provide intensive care in an special unit.
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PMID:[Neonatal listeriosis. Presentation of nine cases (author's transl)]. 93 66

Listeria infections is an important cause of sepsis and meningitis in renal transplant patients. Prompt recognition and aggressive therapy are required to control this life-threatening infection. In 1972, one case of listeriosis occurred in a renal transplant recipient in our center; 1974, six more cases were detected within a period of nine months. All seven patients had Listeria sepsis, and three of the seven patients had both sepsis and meningitis. Antibiotic treatment resulted in remarkable improvement in the clinical state of all the patients in this study. Two patients later died of other unrelated causes.
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PMID:Listeria sepsis and meningitis: A complication of renal transplantation. 110 38

During 1967 to 1985, three cases of listeriosis were reported in Algeria; at that time Listeria monocytogenes caused several thousand cases of meningitis and sepsis in the world. In order to determine the frequency and bacteriologic characteristics of strain isolated in Algeria, a prospective investigation was carried from 1985 to 1989 in humans and animals samples. Sensitivity tests to antibiotics (MIC) point out that all isolates strains are resistant to cephalosporins (first and third generation), but are susceptible to Ampicillin and Gentamicin which ought to constitute the treatment basis of listeriosis.
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PMID:[Prospective study of Listeria in humans and animals]. 130 33

Listeriosis is a not uncommon infection in humans, usually associated with immunodeficient states and with newborns. However, relatively few cases have been reported in HIV-infected patients. This scarcity of reported cases has aroused interest in the association of listeriosis and AIDS. In this paper we present a case of meningitis and septicemia caused by Listeria monocytogenes in a female patient with AIDS. A review of recent medical literature indicates that association of listeriosis and AIDS may be more common than it seems. Recent research in host-parasite interaction in listerial infection suggests an important role for tumor necrosis factor (TNF) and for integralin, a bacterial protein, in modulating listerial disease in AIDS patients. Inadequate diagnosis may be in part responsible for the scarcity of reports.
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PMID:Listeriosis and AIDS: case report and literature review. 134 13

Between January 1985 and December 1990, 233 cases of human listeriosis were reported to the Listeria Reference Centre of Belgium. Foeto-maternal infections (88 cases) and septicemia in adults (88 cases) were the most frequent clinical manifestations, followed by CNS infections (40 cases). 71.7% of the patients presented a concurrent condition which favoured the triggering of the disease. No correlation was found between the isolation of L. monocytogenes in patients and their occupation or their animal environment. The predominant serovar was 4b (70%). On the other hand, the Reference Centre also examined 1412 foodstuffs for the presence of L. monocytogenes: 16.9% (9/53) of cooked chicken products, 15.4% (73/473) of soft cheeses and 6.9% (62/886) of cooked meat products were positive (presence of L. monocytogenes in 25 g). The contamination level of these ready-to-eat foodstuffs ranged from less than 10 cfu L. monocytogenes/g. to 10(6) cfu/g. 54.1% of the isolated strains belonged to serovar 1/2a.
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PMID:Clinical and epidemiological aspects of Listeriosis in Belgium, 1985-1990. 175 27


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