Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

491 cases of non typhoidal salmonella infections were studied in the Rouen Hospital University Centre. Affected patients are mainly children who usually present mild febrile gastroenteritis. Severe forms with septicemia, enteric fever, or focal manifestations, usually occur in adults. In nearly half the cases an underlying disease or another predisposing condition was found. In these cases, the mortality rate was increased. Antibiotic therapy prolonged post-convalescent excretion of salmonellae. Adequate diet and hygiene are sufficient in mild forms. Antibiotics should be used only in acute salmonella infections.
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PMID:[Non typhoidal Salmonella infections: a clinical study of 491 cases (author's transl)]. 628 7

Ceftazidime (CAZ) was evaluated for its safety and efficacy in 31 children. Of the 25 confirmed bacterial infections, 23 were cured by the CAZ therapy (efficacy rate, 92%). CAZ was assessed as effective in acute pharyngitis with vomiting (4), acute laryngitis (1), pneumonia (8), urinary tract infections (5), acute gastroenteritis (1), infection accompanying acute leukemia (septicemia suspected) (1), acute purulent meningitis (2) and abscess of the lateral cervical cyst (1). The main pathogens which responded to CAZ were H. influenzae, S. pyogenes, E. coli and P. aeruginosa. As adverse events, mild melena with prolonged prothrombin time (1) was found to be associated with the CAZ therapy. Half-life of the CAZ serum level was 0.97 +/- 0.10 hours, and urinary excretion was high. Penetration into the CSF in 2 cases of acute purulent meningitis was satisfactory. The data suggest that CAZ is a safe and effective injectable antibiotic when used in children with infections of CAZ-susceptible bacteria including P. aeruginosa.
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PMID:[Clinical evaluation of ceftazidime in the treatment of pediatric infections]. 637 50

Two complications of herniography are presented: a hematoma of bowel causing intestinal obstruction, and a cellulitis of the abdominal wall causing septicemia. A technical error probably caused the hematoma and gastroenteritis played a role in the cellulitis. We have now narrowed our indications for herniography. We think it should be reserved for more difficult diagnostic problems such as recurrent inguinal hernia, recurrent hydrocele or eventration of the diaphragm.
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PMID:Hematoma of bowel and cellulitis of the abdominal wall complicating herniography. 644 64

A case of meningitis by Yersinia enterocolitica in a patient with thalassemia major is described. The Yersinia has been identified both in the cerebrospinal fluid and in the feces. The clinic syndrome began with gastroenteritis and was suddenly complicated by septicemia and meningitis. In spite of a prompt and specific antibiotic therapy, the disease led the patient to death.
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PMID:Fatal Yersinia enterocolitica meningitis in thalassemia major. 646 58

A case of Kingella kingae septicemia following acute gastroenteritis is described. Intravenous antibiotic treatment with mezlocillin and tobramycin led to rapid and sustained recovery. The infection with Kingella kingae may have been food-borne.
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PMID:Septicemia caused by Kingella kingae. 646 71

A chart review was made of 24 neonates less than one month of age with culture-proven enteroviral infection. The seasonal distribution was summer and fall. An antecedent illness was common in the mother or other family members. One patient had a mild gastroenteritis. Three categories of severe disease were noted: (a) meningitis accounted for 50 per cent of the illnesses; (b) myocarditis for 25 per cent of the illnesses; and (c) the remainder presented with a severe sepsis-like illness. High mortality rate was associated with low birth weight and low gestational age.
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PMID:Enterovirus infections in the neonate. 682 23

In the past decade, there has been a dramatic increase in the number of reported cases of clinical illness from noncholera (marine) vibrio infections, leading to a greater recognition of this potentially lethal disease. The wide spectrum of pathogenicity of this organism is reflected in the six cases in this report, varying from simple gastroenteritis to focal necrotizing cellulitis to fatal septicemia. We have reviewed the fundamental clinical differences between Vibrio vulnificus and other noncholera vibrio infections. Physicians treating patients with a history of exposure to coastal waters and/or seafood should be aware of the clinical features and the potential for significant morbidity and mortality of associated Vibrio vulnificus infections.
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PMID:Marine noncholera Vibrio infections in Florida. 682 95

During 1981, we treated 20 infants, less than 24 months old, for nontyphoid Salmonella (NTSal) gastroenteritis (GE). Blood cultures were obtained in 17 cases, and Salmonella bacteremia was demonstrated in 8 (47%). Of the 13 children 3 to 24 months of age, 7 (54%) had positive blood cultures. One child (8 months old) appeared septic. The patients with bacteremia were treated with parenteral ampicillin. All 20 infants recovered, and no focal infectious complications occurred. The incidence of bacteremia in NTSal GE is highest in children under 2 years of age. Previous reports have shown that the peak incidence occurs among infants less than 3 months of age. An infant with Salmonella bacteremia may be afebrile and show no symptoms of sepsis. In most cases, bacteremia is transient and does not alter the course of NTSal GE, but it may result in life-threatening complications such as septicemia and meningitis. Therefore we believe an infant with NTSal GE under 3 months old should have a blood culture and receive antibiotic treatment.
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PMID:Treatment of Salmonella gastroenteritis in infants. The significance of bacteremia. 688 90

A case of fulminant meningococcal septicemia is reported in which an acute gastroenteritis was the presenting symptom. Disseminated intravascular coagulation, profound hypotension and a haemorrhagic skin rash were the dominant clinical features. Successful treatment was directed towards the replacement of coagulation factors, treatment of the underlying infection and reversal of hypotension with the inotropic agent, dopamine. Corticosteroids were used in pharmacological doses, but heparin was not used. The pathogenesis of several abnormalities in this disease is briefly reviewed.
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PMID:Fulminant meningococcemia. 694 45

We report a case of salmonella gastroenteritis with recurrent fever and sepsis, slight transient lumbar pain and positive 67Ga-citrate scintigraphy. The 67Ga scan made a major contribution to the positive diagnosis of a subclinical spondylodiscit and to the correct treatment leading to the disappearance of the infectious foci.
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PMID:Positive 67Ga-citrate scintigraphy: vertebral, satellite lymph node and gallbladder foci in a case of gastroenteritis with salmonella. 695 Aug 98


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