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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pasteurella multocida causes hemorrhagic septicemia in many domestic and wild animals. The most common human infection with P multocida is a local cellulitis following animal-inflicted wounds, preponderantly cat bites and scractches. The typical clinical manifestations and complications have been well described previously. We present three cases of pulmonary pasteurellosis that were recently evaluated by the infectious diseases service at Barnes Hospital. In three additional cases, the technologists in the microbiology laboratory isolated P multocida from respiratory tract secretions.
JAMA 1979 Oct 12
PMID:Human pulmonary pasteurellosis. 58 10

Septicemic melioidosis in association with acute influenza A was diagnosed in a Vietnam veteran. The case illustrates that activation of melioidosis can occur long after exposure to a known endemic area and may be precipitated by infections with other common pathogens. Hence, physicians must maintain a high index of suspicion of melioidosis when dealing with unexplained sepsis in Vietnam veterans. Prolonged therapy with appropriate antimicrobial agents is needed to eradicate this infection.
JAMA 1978 Aug 25
PMID:Septicemic melioidosis. Occurrence following acute influenza A six years after exposure in Vietnam. 67 9

The posttransplant courses of 27 chronic dialysis patients with 29 grafts who had undergone pretransplant bilateral nephrectomy were compared to those of 49 patients with 55 transplant who had no pretransplant surgery during the same time period. The latter had better survival and fewer rejection episodes (P less than .05). The six patients who died of bacterial sepsis after transplantation all had pretransplant surgery. The frequency of post transplant hypertension was similar in both groups. Apparently, pretransplant bilateral nephrectomy offers no advantage to the patient awaiting an allograft.
JAMA 1976 Apr 19
PMID:Cost-benefit ratio of pretransplant bilateral nephrectomy. 81 75

Serial measurements of coagulation activity, platelet counts, and platelet aggregation were done in patients with full-thickness burns involving 25% or more of body surface area to detect specific changes that might correlate with the onset of septicemia. Mean and maximal values for prothrombin time, partial thromboplastin time, thrombin time, activities of factor V and factor VIII, and concentrations of fibrinogen and fibrinogen-related antigens observed in the presence of bacterial septicemia did not differ significantly from those observed in the absence of septicemia. Mean platelet counts were significantly less with sepsis, but values in individual subjects were not indicative of the presence of septicemia. By contrast, platelet aggregation in response to adenosine diphosphate, epinephrine, and collagen always became severely abnormal with the onset of septicemia but not in the absence of sepsis.
JAMA 1976 Mar 22
PMID:Platelet aggregation as a sign of septicemia in thermal injury. A prospective study. 94 30

Four patients with acute cholangitis were seen, all of whom died following cholecystostomy or cholecystoduodenostomy. The diagnosis of cholangitis is frequently missed in elderly patients with jaundice and sepsis. Cholecystostomy, in the face of cholangitis without documentation of patency of the cystic duct, is uniformly fatal. Diagnosis of cholangitis should be confirmed and immediately followed by adequate common duct drainage. Finally, immediate reoperation, rather than antibiotic manipulation, is advised to establish common duct drainage in those patients who do not respond to cholecystostomy within 24 hours.
JAMA 1976 May 31
PMID:Cholecystostomy hazard in acute cholangitis. 94 48

Asplenic patients or those who have undergone splenectomy are prone to overwhelming and often fatal sepsis, which is sometimes associated with disseminated intravascular coagulopathies. Although several pathogens are involved, the most common organism found in these subjects is the pneumococcus, and the infections respond poorly to antibiotic therapy.
JAMA 1976 Sep 20
PMID:Immunological impairment and susceptibility to infection after splenectomy. 98 94

Severe splenomegaly and anemia developed in a 5-year-old girl with diffuse lymphangiomatosis of the upper part of the body. Radioisotope scanning and celiac angiography demonstrated lymphangiomatosis of the spleen, a rare but diagnosable condition. Intractable infection in areas of ulcerated skin led to her death from overwhelming sepsis.
JAMA 1976 Nov 15
PMID:Lymphangiomatosis with splenic involvement. 98 35

During January and February 1975, nine patients on a single ward of a rural Tennessee hospital unexpectedly developed sepsis. The aseptic technique employed in the management of intravenous infusions was implicated. Pseudomonas cepacia was recovered from the following: bloodstream, inuse intravenous infusions and the antiseptic, aqueous benzalkonium chloride. The outbreak again calls attention to the infection risk associated with the use of this product. Selection of less hazardous antiseptics and disinfectants is strongly recommended.
JAMA 1976 Nov 22
PMID:Contaminated aqueous benzalkonium chloride. An unnecessary hospital infection hazard. 98 60

Prolonged Escherichia coli bacteremia occurred as a complication of pyelonephritis in two patients with abnormal hemoglobins (SC and SS), despite "appropriate" antibiotic therapy. Careful investigation in each case failed to account for the persistent sepsis. Pyogenic arthritis ultimately developed in both patients.
JAMA 1975 Nov 17
PMID:Hemoglobinopathy with prolonged bactermia. A report of two cases. 110 36

Listeria infections is an important cause of sepsis and meningitis in renal transplant patients. Prompt recognition and aggressive therapy are required to control this life-threatening infection. In 1972, one case of listeriosis occurred in a renal transplant recipient in our center; 1974, six more cases were detected within a period of nine months. All seven patients had Listeria sepsis, and three of the seven patients had both sepsis and meningitis. Antibiotic treatment resulted in remarkable improvement in the clinical state of all the patients in this study. Two patients later died of other unrelated causes.
JAMA 1975 Nov 24
PMID:Listeria sepsis and meningitis: A complication of renal transplantation. 110 38


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