Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036572 (seizures)
80,221 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 5355
MRI 3192
GABA 2533
CA1 1758
Mol 1441
She 1416
CA3 1413
NMDA receptor 786
CSF 684
Pol 453
glial fibrillary acidic protein 453
axonal 406
X-linked 397
DBA 390
SCN1A 389
GABA(A) receptor 385
insulin 365
olfactory 363
glutamate receptor 357
ATP 353
sodium channel 335
brain-derived neurotrophic factor 301
cytokine 290
c-fos 287
acetylcholinesterase 266
somatostatin 264
Rett syndrome 256
mTOR 253
parvalbumin 252
calcium channel 235
neuropeptide Y 220
ionotropic 216
ACTH 212
nitric oxide synthase 212
FDG 205
caspase-3 201
beta-endorphin 194
AED 190
glutamic acid decarboxylase 189
vasopressin 188
prolactin 184
voltage-gated sodium channel 170
hemoglobin 165
REM 161
endoplasmic reticulum 156
ATPase 154
superoxide dismutase 153
IL-6 152
TNF 150
KCNQ2 148
NMR 147
TSC2 145
asymmetrical 139
HBA 134
catalase 131
TSC1 131
tumor necrosis factor 130
GSH 129
MES 127
CA2 127
metabotropic glutamate receptor 122
CA4 121
cytochrome P450 121
alkaline phosphatase 119
albumin 119
Gen 117
opioid receptor 114
CDKL5 113
P-glycoprotein 113
glutamate decarboxylase 111
KCC2 109
GAD 108
GABA transaminase 105
NR1 105
NR2B 104
amyloid precursor protein 104
5-hydroxytryptamine 103
N-acetylaspartate 103
Bcl-2 101
adenosine receptor 99
more...
Disease
epilepsy 29183
fits 5070
status epilepticus 4827
temporal lobe epilepsy 3668
encephalopathy 3228
depression 2525
stroke 2225
tumor 1863
encephalitis 1621
coma 1600
mental retardation 1557
mental retardation 1539
developmental delay 1444
hypertension 1365
complex partial seizures 1316
cognitive impairment 1168
psychosis 1043
focal epilepsy 976
cancer 898
dysplasia 892
ischemia 888
hemiparesis 885
confusion 874
autism 864
dementia 805
febrile convulsions 776
tuberous sclerosis 735
West 721
hydrocephalus 712
migraine 693
Alzheimer's disease 681
meningitis 660
Lennox-Gastaut syndrome 647
hypoglycemia 643
generalized seizure 550
hallucinations 534
Lennox-Gastaut syndrome 527
neurological disease 524
glioma 521
schizophrenia 496
diabetes 487
cerebral palsy 438
blindness 433
petit mal 426
juvenile myoclonic epilepsy 420
aphasia 416
brain atrophy 393
DBA 391
rash 385
systemic lupus erythematosus 384
multiple sclerosis 376
brain tumor 365
eclampsia 364
renal failure 347
aggression 345
cerebral ischemia 342
mental illness 338
subarachnoid hemorrhage 326
pneumonia 323
delirium 322
Posterior 314
sepsis 306
preeclampsia 298
Rett syndrome 293
memory impairment 283
vasculitis 282
thrombocytopenia 281
alcoholism 278
anemia 273
Parkinson's disease 273
sepsis 268
SWS 265
meningioma 257
astrocytoma 257
HIV 254
amnesia 253
leukoencephalopathy 249
nystagmus 248
myoclonus epilepsy 246
hamartoma 242
more...
Symptom
seizures 80221
headache 2841
ataxia 1522
pain 1092
vomiting 1082
anesthesia 1034
hypotonia 985
myoclonus 928
sleepiness 776
tonic-clonic seizure 741
weakness 740
tremor 650
nausea 556
dizziness 554
syncope 544
partial seizure 519
lethargy 497
agitation 436
fatigue 414
hypothermia 396
diarrhea 384
dystonia 367
hemiplegia 364
spasticity 363
clonus 307
respiratory distress 249
insomnia 233
abdominal pain 223
analgesia 205
paresis 196
memory loss 193
dysarthria 190
vertigo 182
cerebellar ataxia 181
collapse 179
tonic seizure 175
stigma 175
cough 168
dyspnea 167
spasm 165
anorexia 156
chorea 141
twitching 133
nausea and vomiting 133
paresthesia 123
discomfort 117
hypertonia 113
cyanosis 109
discomfort 109
constipation 99
consciousness disturbance 95
blurred vision 90
catatonia 88
hypercapnia 86
polydipsia 80
numbness 78
hepatomegaly 77
ophthalmoplegia 77
chest pain 74
Ill 70
incoordination 69
asthenia 68
tachypnea 68
functional recovery 66
hepatosplenomegaly 66
paraparesis 66
pallor 58
polyuria 57
myalgia 57
tinnitus 57
shortness of breath 53
back pain 51
ataxic gait 49
enuresis 49
thinning 49
neck stiffness 48
apathy 46
overweight 44
arthralgia 43
hyperoxia 42
more...
Drug
CSF 685
Phenytoin 351
caffeine 252
Kainic acid 196
Gabapentin 145
Pilocarpine 131
Vitamin B 125
Monit 113
Ethanol 113
Dermatol 106
lysine 93
Zonisamide 92
Sodium valproate 85
pyridoxal phosphate 84
MAP 76
Propofol 76
Cardiovasc 65
PCP 57
ampicillin 54
vitamin E 54
Pregabalin 54
Theophylline 48
Rufinamide 46
GVG 46
NADH 45
DPA 44
ascorbate 41
Keppra 39
Spectrum 38
Magnesium sulfate 38
Isoniazid 38
Atropine 38
Portal 36
Nephron 36
MgSO4 35
Frontal 35
Spectrum 34
Fosphenytoin 33
Metrizamide 31
DBS 30
9-THC 29
ROC 27
Leaf 26
Dilantin 26
CTX 26
Clonidine 26
Meropenem 25
Meropenem 24
PTH 24
Tacrolimus 24
Stiripentol 23
ROS 23
TMS 23
Dial 21
Flurothyl 20
Progabide 20
IPM 20
Histamine 19
Asthma 19
Scopolamine 19
p75 18
Gel 18
ABC 18
Bumetanide 18
Reserpine 18
ICI 18
ALA 17
Vitamin E 17
ENT 17
EE2 17
Topamax 16
Valproic Acid 16
Ganaxolone 16
DDAVP 16
citric acid 15
Piracetam 15
Indomethacin 15
IL-2 15
DDAVP 15
Bupivacaine 15
more...
Enzyme
acetylcholinesterase 343
mitogen-activated protein kinase 202
superoxide dismutase 179
catalase 173
ATPase 170
caspase-3 168
ERK 153
protein kinase 147
cholinesterase 132
creatine kinase 127
alkaline phosphatase 119
glutamate decarboxylase 118
P-glycoprotein 113
monoamine oxidase 111
protein kinase C 104
NO synthase 98
GABA transaminase 91
calcineurin 85
glutathione peroxidase 83
glutamine synthetase 78
carbonic anhydrase 70
peroxidase 69
cytochrome oxidase 67
complex I 65
aspartate aminotransferase 61
lactate dehydrogenase 60
PCP 57
ACS 55
tyrosine hydroxylase 53
alanine aminotransferase 53
NOS 52
adenosine kinase 51
phosphodiesterase 48
choline acetyltransferase 47
tissue plasminogen activator 44
reverse transcriptase 44
PHT 42
CaMKII 39
focal adhesion kinase 39
biotinidase 38
pyruvate dehydrogenase 38
APC 36
thrombin 35
phospholipase C 35
asparaginase 34
phospholipase A2 33
renin 33
adenylate cyclase 32
thyroid peroxidase 32
proteasome 32
glutamate dehydrogenase 31
succinic semialdehyde dehydrogenase 31
glutamate dehydrogenase 31
succinate dehydrogenase 31
alcohol dehydrogenase 31
sulfite oxidase 31
sulfite oxidase 31
glutamate dehydrogenase 31
MEK 29
phosphatidylinositol 3-kinase 29
adenosine deaminase 29
ACE 29
beta-galactosidase 29
luciferase 29
CPS 29
adenosine deaminase 28
pyruvate dehydrogenase 28
pyruvate dehydrogenase 28
glutathione reductase 26
aldehyde dehydrogenase 26
ceruloplasmin 26
NADPH-diaphorase 25
CYP3A4 25
glutathione S-transferase 25
5alpha-reductase 24
enolase 24
thromboplastin 24
GSK 24
5alpha-reductase 24
CPT 22
more...
Compound
Dec 5694
Clin 5219
GABA 2589
GABA 2560
sodium 2191
glutamate 2181
calcium 1783
glucose 1283
water 1273
DNA 1089
gamma-aminobutyric acid 1057
oxygen 1020
potassium 931
NMDA 760
ethanol 740
His 703
Cardiol 668
Valproic acid 490
AMPA 481
DPH 422
nitric oxide 401
Neuronal 395
arginine 393
DBA 390
DBA 390
DBA 390
phosphate 390
ATP 353
Neurotol 340
sulfate 302
Levetiracetam 292
zinc 278
5-HT 277
Diazepam 265
caffeine 255
Lamotrigine 251
glutamine 242
ACTH 232
acetate 231
serine 215
leucine 215
Luminal 215
ammonia 204
urea 201
Cereb 196
Kainic acid 196
Kainic acid 196
creatinine 195
tyrosine 185
iron 183
methionine 181
CO2 180
Valproic acid 176
noradrenaline 176
Topiramate 174
fluorine 173
Vigabatrin 172
nitrogen 169
vitamin D 164
Glutamate 163
Mg2+ 162
hydrogen 157
aspartic acid 155
TNF 150
alanine 150
galactose 149
tryptophan 148
bromide 140
tryptophan 136
GSH 136
GSH 136
tryptophan 133
tryptophan 133
Pilocarpine 130
MES 127
MES 127
copper 127
DSM 123
homocysteine 123
salt 123
more...