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Query: UMLS:C0036572 (seizures)
 80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors present the result of psychopathological analysis of a group of 91 patients who suffered from epileptic seizures of definitely or probably established posttraumatic etiology. Mental disturbances in these patients were differentiated into sporadic psychopathological phenomena and chronic psychiatric syndromes. Sporadic episodes, which the authors identify with "psychical seizures", concerned 58 patients. They were manifested by psychomotor or psychosensory seizures, dismnesia and disthymia. Chronic psycho-organic syndromes were diagnosed in 85 patients. They were: dementive, characteropathic, dementive-characteropathic, oligophrenic and temporal lobe syndrome (according to Landolt). Psychopathological picture of posstraumatic epilepsy does not appear to be specific for the etiological factor. The relatively high number of patients with partial seizures of mixed symptomatology may indicate that head traumas frequently damage the limbic structures of the brain. Confirmed is the observation of other authors that there is a correlation between the temporal localization of epileptic focus and character disturbances.
Pol Med Sci Hist Bull
PMID:Psychopathology of posttraumatic epilepsy in the light of personal clinical observation. 99 51

Depressive behavioral effects of acetylcholine (10 mug ivtr) and physostigmine (0.3 mg/kg ip), and prolongation of the duration of electrogenic seizures produced by the drugs were prevented by intraperitoneal or intraventricular administration of FDP (0.5 mg/kg or 5 mug resp.). The peptides did not affect the brain acetylcholine level and did not influence the inhibitory effect of physostygmine on AChE activity.
Pol J Pharmacol Pharm
PMID:Influence of fibrinogen degradation products (FDP) on the central action of acetylcholine. 101 88

The author reviews the pertinent literature and the results of own investigations in migraine. EEG changes in migraine are observed in nearly 50% of cases during attacks as well as in the periods free of pains. Most investigations were done in the periods between attacks. The H response characteristic of migraine was found by the author in 25% of cases only. Focal changes were present in 30% of cases. They were not related to the side of the pain, its duration and the form of migraine. Seizure activity was never observed. The author regards isolation of the so-called dysrhythmic form of migraine as not justified. EEG changes suggest--according to the author--that migraine is a primary cerebral and only secondarily a vascular disorder.
Neurol Neurochir Pol
PMID:[Electroencephalographic studies in migraine]. 115 64

The author describes 6 cases in which an unquestionable temporal correlation was observed between the appearance of epileptic seizures and the action of certain allergens. Allergy is considered only rarely as a cause of epileptic seizures. The pathological mechanisms of such seizures seems to be a complex one. In some cases there is probably a direct influence of allergens or biochemical agents released by them on the central nervous system. Data from the literature and own observations show that not infrequently partial complex seisures appear in connection with allergy, besides generalized attacks. The former are frequently a response to the action of chemical and pharmaceutical allergens. Sometimes, anticonvulsants are the agents releasing epileptic seizures. The diagnosis of allergic epilepsy is facilitated by coexistence of local or systemic signs of allergy. The prognosis depends on early recognition of the cause of attacks and appropriate therapeutic management.
Neurol Neurochir Pol
PMID:[Allergologic aspects of epilepsy]. 116 33

The authors determined the amounts of oestrone, oestradiol, oestriol, alpha and beta pregnanediol, and pregnanetriol in 24-hour urine of 11 women with epileptic seizures occurring two and one day before the onset of menstruation, and in 7 women with seizures not dependent on the menstrual cycle. Determinations of these hormons were done during three successive menstrual cycles on the 2nd and 1st day before the onset of bleeding. In both groups a significant decrease was observed in the urinary levels of oestradiol and oestriol as compared with normal values. On the other hand, the amount of excreted oestrone was only slightly lowered in relation to the amount of this hormone excreted by controls. A significant decrease in the amounts of alpha pregnanediol (the difference being statistically significant at p less than 0.01 level) was observed two days before menstruation. On the other hand, pregnanetriol was decreased only in women in whom the seizures showed no temporal correlation with the stage of the menstrual cycle. The authors suggest that the observed reduction in the metabolites of progesterone in both groups was associated with an increased seizure readiness of the brain on the days preceding menstrual bleeding.
Neurol Neurochir Pol
PMID:[Urinary excretion of estrogen fractions, alpha and beta pregnanediol and pregnanetriol in women with epileptic seizures during the premenstrual period]. 117 86

The authors determined the amounts of free and total 17-hydroxycorticosteroids (17-OHCS) and 17-ketosteroids (17-KS) in the urine of 11 women in whom epileptic seizures occurred most frequently on the 2nd and 1st day before menstruation and in 7 women with seizures showing no such correlation with the menstrual cycle. A statistically significant decrease of 17-KS was demonstrated in women with premenstrual seizures. In both groups of women the amounts of free 17-OHCS were near the lower normal range, while the amounts of total 17-OHCS were reduced and the obtained results compared with the accepted normal values showed statistically significant differences (p less than 0.01). The obtained results are, however, insufficient for assuming that these hormones play an important role in the mechanism of seizure release in premenstrual period. The authors think, on the other hand, that the statistically significant fall in 17-KS in women with premenstrual seizures may play some role among other factors in the mechanism of seizure release.
Neurol Neurochir Pol
PMID:[Urinary excretion of 17-hydroxycorticosteroids and 17-ketosteroids in women with epileptic seizures during the premenstrual period]. 117 85

In 62 women the course of epilepsy was analysed at the age of puberty from 11 to 15 years of life. In 19 cases the course of the disease remained unchanged at that time, in 20 cases the seizures disappeared or became less frequent, in 20 cases the frequency of seizures increased, other types of seizures developed, or seizures present previously in childhood reappeared. The unfavourable change in the course of disease was observed more often in girls with onset of the disease at an early age, frequent seizures at the beginning of the disease, partial combined seizures, neurological and psychic abnormalities and with delayed menarche in relation to the general population.
Neurol Neurochir Pol
PMID:[The course of epilepsy in girls at the age of puberty]. 118 50

The authors report a boy aged 9 years in whom a giant meningioma of the small wing of the sphenoidal bone was removed surgically. Attention is called to the rarity of these tumours in the first decade of life. Developmental retardation, speech beginning at the age of 4 years, large head and epileptic seizures developing at the age of 7 years without signs of intracranial hypertension suggested the possibility of organic brain disease and development of massive hemiparesis, speech disturbances and choked disc in the last period of the disease were the cause of referral of the child to a neurosurgical unit. Plain skull films and angiography demonstrated changes typical of raised intracranial pressure and presence of an expanding lesion in the left cerebral hemisphere. Meningioma was found on operation hidden within the left frontal and temporal lobes but connected by means of a narrow band to the dura of the small wing of the sphenoidal bone. A good result was obtained. Follow-up examination after 2 years demonstrated slight neurological abnormalities and a very good general state of the child.
Neurol Neurochir Pol
PMID:[Case of giant meningioma of the small wing of the sphenoid bone in a 9-year-old boy]. 118 62

In the light of pertinent literature the authors discuss two interesting cases of developmental anomalies of cerebral vessels demonstrated by means of angiography which were the cause of epileptic seizures and progressive dementia.
Neurol Neurochir Pol
PMID:[Epileptic seizures in children caused by developmental anomalies of meningocerebral vessels]. 120 6

PHENT (20 and 100 mug ivc) affects the central action of 5-HT (0-1, 25 and 250 mug) in rats which shows itself in potentiation of 5-HT-induced inhibition of spontaneous locomotor and exploratory activities and in the prolongation of hexobarbital sleeping time. In case of postamphetamine hyperactivity and body temperature, 5-HT acts antagonistically to a lower PHENT dose and synergistically to a higher dose of this compound. No affect of 5-HT on a slight antistereotypy action of PHENT has been stated. Neither compound affects electrical seizures.
Pol J Pharmacol Pharm 1975 Oct
PMID:The influence of phentolamine on the central activity of 5-hydroxytryptamine in rat. 123 51


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