Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0036572 (
seizures
)
80,221
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Invasion of the central nervous system by the larvae of Tenia
Solium
classically leads to severe illness. In some instances, however, the course is protracted and benign. The authors report on two patients with cysticercosis cerebri, revealed by delayed
seizures
without cerebral hypertension or any other manifestation. Computerized tomography established the diagnosis by demonstrating calcifications disseminated throughout the cerebral parenchyma. Such calcifications result from encapsulation of dead larvae. The possible diversity of the anatomic lesions caused directly or indirectly by the parasite explains why clinical manifestations are polymorphic. Diagnostic procedures are discussed.
...
PMID:[Late epilepsy in cerebral cysticercosis. 2 cases confirmed by tomodensitometry]. 630 78
Cerebral cysticercosis is the result of infestation of the brain with the larval stage of the intestinal tape worm Taenia
Solium
. The disease, endemic in some parts of the world, especially Mexico, South America, India, Eastern Europe, is still encountered practically all over the world. There appear to be distinct geographical variations not only in the incidence but also the pattern of the disease. The commonly accepted modes of infection do not stand a critical analysis of available epidemiological data. The brain is a site of predilection for this infestation, where it results in meningeal racemose, parenchymatous ventricular or mixed types of lesions. It may thus produce meningo-encephalitis, granulomatous meningitis, ependymitis , focal granulomas, solitary or multiple parenchymatous cysts, hydrocephalus or a combination of these. Clinically its manifestations are protean and often perplexing, consisting, either alone or in combination, of raised intracranial pressure, focal or multifocal or generalized epileptic
seizures
, signs and symptoms of a focal mass lesion, hydrocephalus or chronic meningo-encephalitis. Important features of the disease are remissions and recurrences. Laboratory diagnostic investigations are generally unrewarding, there being so far, no single completely reliable test. Recent CAT scan studies have been helpful but not always diagnostic. There is no known medical treatment. Excision of a solitary parenchymatous or intraventricular lesion provides gratifying results but the management of diffuse lesions, presenting with raised intracranial pressure ("pseudo-tumour") is often frustrating. Extensive bilateral decompression, with or without an additional thecoperitoneal shunt, is helpful in some of these cases.
...
PMID:Cerebral cysticercosis. 637 90
Since 1985 infection by suin tapeworm Taenia
Solium
seems to have disappeared in Italy, but patients may still exist which have contracted many years ago the disease that has followed its natural course. We report the case of an Italian, 50 year-old-man with neurocysticercosis presenting with generalized
seizures
. CT and MR showed typical calcific and cystic lesions in the brain. Rx scans of muscles revealed the presence of fusisorm calcific lesions suggestive for cysticercosis and the serum levels of specific antibodies confirmed the diagnosis. The patient was treated with albendazole with no regression of cerebral lesions after one month, but simultaneous treatment with antiepileptic drugs was able to control completely neurologic symptoms.
...
PMID:[Neurocysticercosis and epilepsy. Description of a clinical case]. 793 59