Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036572 (seizures)
80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Medicosocial aspects of 2,000 patients with epilepsy were outlined on the basis of international classification of epilepsies and epileptic seizures. 1. The incidence of secondary generalized epilepsy was higher compared with that reported previously. It was possible that we have been dealing with rather intractable epilepsy. Non-convulsive epileptic seizures should be treated as intensively as convulsive attacks. 2. Contrary to primary generalized epilepsy, secondary generalized epilepsy and partial epilepsy, a part of which was complex partial seizures, were more prone to be associated with psychological difficulties. 3. The rate of normal mentality was apparently proportional to the actual ease of employment among adult patients. Fortunately, the general attitude of education toward younger people with epilepsy was seemingly generous. However, the marital status of both sexes was far from satisfactory. The stigma might have been felt more by adult patients than younger ones. 4. It appeared to be conceivable that two-thirds of the people with epilepsy are treatable to a certain extent by adequate regimens while one-tenth are obliged to stay in residential centers for a lengthy period of time. Thus, various rehabilitation activities are indicated for one-fourth of the patient population. Actual strategy for rehabilitation of epileptics should be individually designed in accordance with the natural history of each epilepsy.
...
PMID:Medicosocial aspect of people with epilepsy in Japan--a survey from standpoint of epilepsy center. 52 Sep 58

Tested a theoretical model that sought to explain the association of stigma to self-esteem among adolescents with epilepsy. The model depicted hypothesized relationships among several characteristics of epilepsy (seizure type, seizure frequency, and duration of epilepsy), perceived stigma, management of disclosure, and self-esteem. Subjects were 64 adolescents 12 to 20 years old with idiopathic epilepsy. In a hierarchical multiple regression analysis, variables were entered into the equation in the order specified a priori by the model. Results showed that the data supported some hypotheses tested in the model: (a) Seizure type and seizure frequency predicted low self-esteem, and (b) the belief that epilepsy is stigmatizing predicted low self-esteem. However, several relationships of major theoretical significance were not realized. Explanations for why some aspects of stigma theory were not supported by the data are offered.
...
PMID:Applying stigma theory to epilepsy: a test of a conceptual model. 143 85

Epilepsy differs from other chronic conditions because of the unpredictability of the seizures, the absence of an absolute diagnostic test other than video-telemetry and the stigma associated with the condition. Working from a hospital base with a biased population, one might be forgiven for thinking that most people with epilepsy have major problems either of seizure control or socially. This is naturally not the case, but the social problems of epilepsy are sufficiently frequent and/or severe to warrant comment. Simply making the diagnosis may produce parental anxiety and guilt. This is often compounded by societal misunderstanding of epilepsy and the incorrect association with mental illness. Furthermore, it is those children or adults who have severe epilepsy who stand out in society, with the tacit implication that all epileptics (people with epilepsy) are like them. There is a societal generalization that all epileptics are the same. It is not appreciated that there are many types of epilepsy (convulsive and non-convulsive) and that epilepsy varies from being very mild to intractable. Treatment also has implications: children and adolescents may not like to take, or be seen to be taking, medication. It is desirable where possible to recommend twice daily dosage with breakfast and dinner. This avoids the need to take medication to school, or in the case of adolescents, to work. In addition, compliance is enhanced with a twice daily dosage. There is without doubt a stigma associated with epilepsy which persists despite being to a less degree than in the past.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:Social aspects of epilepsy in childhood and adolescence. 321 3

With proper diagnosis and management, the frequency of pseudoseizures can be reduced or eliminated. Emotional factors, whether internal or external, can precipitate pseudoseizures. The goals of therapy are to identify pseudoseizures and resolve the conflicts that manifest them; both psychiatric intervention and hypnosis have produced good results in the treatment of pseudoseizures. Nurses are involved in all aspects of care from observation of seizure activity to assessment and implementation of an appropriate plan of care. The care plan should include helping the patient and his family understand the meaning of the patient's pseudoseizures, recognizing the effect of stigma on the patient and his family, assessing the coping skills of the patient and his family, and setting realistic expectations for the patient regarding prognosis and treatment.
...
PMID:Hysterical seizures or pseudoseizures. 655 9

To study the extent to which persons with epilepsy feel stigmatized by the disorder, a sample of 445 individuals with epilepsy is analyzed. By first defining stigma in quantifiable terms and then by assessing the prevalence of stigma among the individuals studied, two alternative models that postulate the causes of stigma are investigated. The first model, a simple medical approach, assumes that because epilepsy is stigmatizing for an individual with the disorder, a direct relationship exists between the severity of the individual's seizure and the perception of stigma. The second model, a sociopsychological approach, assumes that the effects of seizure severity on the perception of stigma are mediated by other individual characteristics. The results of the study suggest, first, that persons with epilepsy do not universally feel stigmatized by the disorder. Second, by investigating the validity of these assumptions with regression and path analysis techniques, the findings support the premise of the sociopsychological model. The relationship between the severity of seizures and the perception of stigma due to the disorder is found to be highly dependent on other characteristics in the individual with epilepsy, such as the perception of employment discrimination, the perception of limitations imposed by the disorder, and the years of school attained by the individual.
...
PMID:The stigma of epilepsy as a self-concept. 739 8

A scale based on underlying core beliefs generated by the experience of epilepsy was developed. The scale, with measures of coping, adaptability, and knowledge, was used to examine the commonly-reported differences in emotional adjustment between patients (EP) and a non-epileptic population (NEP). The EP had significantly lower perceived self efficacy and was more depressed and anxious than the NEP controls. The NEP showed greater knowledge of medical aspects of epilepsy than the EP. Positive correlations between scale values and measures of mastery, self esteem, affect balance, felt stigma and impact of epilepsy were found. Factor analysis produced a three factor solution of emotion, knowledge and anxiety which explained 61.6% of the variance in scores. Results are discussed in terms of Bandura's theory of self efficacy as the motivating and sustaining force in the ability to change behaviour. Core beliefs are central to both the development and maintenance of anxiety and depression in epilepsy patients and need to be addressed in any attempts at remedial intervention.
Seizure 1995 Sep
PMID:Development of a scale to measure core beliefs and perceived self efficacy in adults with epilepsy. 758 58

Epilepsy is, in the majority of cases, a short-lived and self-limiting clinical condition. However, individuals labelled as epileptic frequently continue to feel stigmatised, even after their seizures remit. This paper describes the nature and extent of stigma in a group of individuals with epilepsy in remission. The distinction between 'felt' and 'enacted' stigma is examined, and found to be supported by the data.
...
PMID:Felt versus enacted stigma: a concept revisited. Evidence from a study of people with epilepsy in remission. 814 Apr 53

As part of a large community-based study, we retrospectively examined the clinical course of epilepsy in an unselected population of people who had a recent history of seizures or were receiving antiepileptic drugs (AEDs). Clinical information was collected from medial records, and information about psychosocial functioning was obtained by means of postal questionnaires sent to identified subjects. The response rate to the postal questionnaire was 71%. There were some deficiencies in the recording of clinical data, which is not unusual since data were taken from records held by primary physicians rather than from hospital clinics. Nevertheless, findings regarding the clinical course of epilepsy corresponded to those of earlier studies. Fifty-seven percent of the sample had had at least a 2-year seizure-free period and 46% of subjects were currently in a remission of at least 2-year duration. There was a clear relationship between current seizure frequency and levels of anxiety and depression, perceived impact of epilepsy, perceived stigma, and marital and employment status. The relationship of seizure frequency and other clinical variables to psychosocial function was explored by multivariate analysis techniques. The amount of variation in scores on the various measures of function accounted for by the clinical variables was small. The most important predictor was current seizure activity, which was the first variable to enter the regression analyses for six of the eight measures of psychosocial function considered. Age at epilepsy onset also emerged as a significant predictor for depression, stigma, and marital status. In individuals with epilepsy in remission, there was little evidence that psychosocial functioning was associated with length of remission, a finding which may in part reflect the nature of this study population. The results indicate that there are several more important predictors of psychopathology and social dysfunction in epilepsy and suggest several implications for treatment interventions.
...
PMID:The clinical course of epilepsy and its psychosocial correlates: findings from a U.K. Community study. 863 25

Epilepsy in children is frequently accompanied by learning, behavioural and psychological difficulties. These difficulties may be compounded by the ignorance and stigma which exists within the community health care and education services. The management of epilepsy in children therefore extends far beyond the use of antiepileptic drugs and must address these additional problems. The establishment of a nurse specialist service in paediatric epilepsy within our hospital has provided a more satisfactory and comprehensive management of these children and, in addition, has facilitated a close liaison with schools, community health personnel and support groups; as a result this has dispelled much of the local ignorance, misunderstanding and stigma surrounding epilepsy.
Seizure 1995 Dec
PMID:The management of epilepsy in children: the role of the clinical nurse specialist. 871 21

Epilepsy is a well-documented consequence of about 150 rare genetic syndromes and malformations of the central nervous system. These syndromes are generally associated with fairly gross defects within the central nervous system and they were thought to be responsible for a small minority of cases. However, improved methods of neuropathological investigations and extensive magnetic resonance imaging studies have revealed a range of disturbances in cortical cytoarchitecture in patients with epileptic seizures previously considered as idiopathic (up to 70% of epilepsy). Structural abnormalities have also been demonstrated in the brain in schizophrenia. These consist of disturbed cortical cytoarchitecture (best described in the temporal lobe) and a diffuse loss of grey matter. The absence of the pathological stigma characteristic of degenerative processes indicates that these structural changes are the result of an abnormal pattern of brain development. The relationship between the type and location of developmental abnormality and the subsequent clinical syndrome (e.g. generalized or localized epilepsy) and the effects of aberrant cortical development on the functional integrity of the adult brain require definition.
...
PMID:Pathology of cortical development and neuropsychiatric disorders. 872 98


1 2 3 4 5 6 7 8 9 10 Next >>