Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036572 (seizures)
 80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cocaine use often has profound effects on the body. Medical complications that may be seen in users include headache, sexual dysfunction, violent behavior, chronic cough, seizures, and myocardial infarction. The type of cocaine used and the method of use often determine the kind of problems that occur. Patients may be reluctant or unable to offer information about their drug use during evaluation, so awareness of the medical consequences of cocaine use and a high index of suspicion are essential.
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PMID:Is your patient using cocaine? Clinical signs that should raise suspicion. 763 Aug 45

The seroprevalence of toxocariasis was investigated in 1997/98 in 1009 schoolchildren (aged 5-12 years) throughout Trinidad. Infection, as measured by titre, was found to be high compared to values obtained from children in other countries. Using an excretory-secretory antigen and performing an ELISA test, it was found that 62.3% of children had an IgG antibody titre of > or = 1:100, indicating exposure to the parasite, while 27.2% had a titre of > or = 1:800, indicating a current or recent infection. Relationships were explored between seroprevalence and host factors including age, sex, school location, and other risk factors including geophagia, thumb-sucking, presence of other gastrointestinal-tract parasitism and pet ownership. There was no significant relationship between age and the presence of current or recent infection (P = 0.746). Boys were significantly more commonly infected than girls as were the attendees of rural schools versus urban schools (P < 0.001). The percentage of seropositivity among children varied widely from school to school. Pet ownership and the absence of pipe-borne water in the household were found to be significantly associated with positive serology (P < 0.05). Clinical symptoms mostly associated with positive serology were eczema, seizures and chronic cough. Recommendations derived from this study include health education in order to increase the public awareness on the transmission of the disease, de-worming all dogs and cats periodically and the curbing of stray dogs and cats. Environmental sanitation measures should include keeping children away from contaminated areas and practising proper hygiene after play.
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PMID:Seroprevalence of toxocariasis in schoolchildren in Trinidad. 1205

Pertussis, also known as whooping cough, is an acute respiratory tract infection that has increased in incidence in recent years. The initial catarrhal stage presents with nonspecific symptoms of malaise, rhinorrhea, sneezing, lacrimation, and mild cough. During the paroxysmal stage, severe outbreaks of coughing often lead to the classic high-pitched whooping sound patients make when gasping for breath. The paroxysmal stage is followed by the convalescent stage and resolution of symptoms. Complications vary by age, with infants more likely to experience severe complications such as apnea, pneumonia, seizures, or death. In adolescents and adults, complications are the result of chronic cough. The diagnosis depends on clinical signs and laboratory testing. Both culture and polymerase chain reaction testing can be used to confirm the diagnosis; serologic testing is not standardized or routinely recommended. Although antibiotics have not shown clear effectiveness in the treatment of pertussis, they eradicate nasal bacterial carriage and may reduce transmission rates. Macrolide antibiotics such as azithromycin are first-line treatments to prevent transmission; trimethoprim/sulfamethoxazole is an alternative in cases of allergy or intolerance to macrolides. Immunization against pertussis is essential for disease prevention. Current recommendations in the United States consist of administering five doses of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine to children before seven years of age, and administering a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) booster between 11 and 18 years of age. Recent efforts have focused on the vaccination of adolescents and adults, with new recommendations for a single dose of the Tdap booster if it has not been previously administered.
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PMID:Pertussis: a reemerging infection. 2436 71

Disseminated tuberculosis involving the uterine cervix and central nervous system is described in a 26-year-old Native American female with new-onset seizures. Her presenting complaint was generalized seizures with associated weight loss, chronic cough, global headache, and malaise. Pelvic examination revealed an exophytic cervical mass consistent with carcinoma. Laboratory results showed anemia, hypoalbuminemia, and radiodensities on chest radiography. Cultures of sputum and cervix were positive for Mycobacterium tuberculosis. Cervical biopsies revealed multiple acid-fast bacilli. Computed tomography of the head showed multiple tuberculomas. The patient was treated with multidrug antituberculous therapy for 6 months, with resolution of seizures and improvement in computed tomographic findings.
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PMID:A case report of disseminated tuberculosis: an unsuspected uterine cervical mass in a young native american woman with new-onset seizure disorder. 2595 May 60

Objective Conversion disorder (CD) is a mental disorder in which patient displays neurological symptoms such as blindness, mutism, paralysis and seizure. It starts when our mind converts our mental stress into a physical symptom. A 15-year-old single white female with chronic cough, which had begun 5 months ago, was brought to our clinic. She had no history of hospitalization. His daily cough was without sputum production or fever, rhinorrhea and stopped during sleep. There was no recent exposure to tobacco smoke or a person with a chronic productive cough. Laboratory tests were normal. She had engaged 4 months ago. Doing sex during engagement is prohibited in her culture but and had anal sex, because of her spouse's trend. Psychotherapy was done and complete recovery was accomplished.
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PMID:Functional Neurological Symptom Disorder: Mismanagement, Misdiagnosis, Chronic Cough Following Sexual Abuse: A Rare Case Report. 2724 90