Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036572 (seizures)
 80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The report contains some results of a study of 18 patients where in 17 cases the authors believe that the convulsive syndrome was due to an infestation by ascarides, soatworms or by a combination of helminths with other enteral helminthosis. In one case intestinal parasitism aggravated the development of frontal epilepsy. It was demonstrated that the removal of helminths leads to an arrest of convulsive seizures, while a new infestation--to their appearance. The authors have attemped to give characteristics of the epileptical syndrome, provocated by ascarides and seat-worms.
 ...
PMID:[Epileptic syndromes in ascariasis and enterobiasis]. 64 14

Orbital cysticercosis is a rare condition. We report here 3 cases with orbital cysticercosis who presented with proptosis and ptosis (Case no. 1 and 2) and focal seizures (Case no. 3). All of them had a vision of 6/6. Diagnosis of cysticercosis was made on CT Scan. The lesions isolated in Cases 1 and 2 and were excised. Drug therapy was given to treat any persisting infestation. Case no 3 had multiple brain cysticerci in addition to the orbital one. However, the patient was lost to follow-up.
 ...
PMID:Orbital cysticercosis. 130 95

Ivermectin, a potent, effective anthelmintic, is easy to administer, has a broad spectrum of action and a wide safety margin. However, no testing has been done in hosts genetically selected for seizure susceptibility which may be more sensitive to the effects of ivermectin than other animals. This was done in the present experiments with seizure prone and seizure resistant mice infested with Syphacia obvelata (pinworm). These subjects were treated daily with oral ivermectin in their drinking water every other week for six weeks, for a total of 21 days. The treatment cleared the mice of the pinworm infestation, but did not alter the seizure susceptibility or binding parameters of [3H]flunitrazepam in either of the selected lines.
 ...
PMID:Effect of chronic ivermectin treatment on GABA receptor function in ethanol withdrawal-seizure prone and resistant mice. 215 65

Cerebral cysticercosis is becoming more common in Australia as the immigrant population from areas of endemic disease increases. The case reported exemplifies the common presentation of this interesting infestation. Treatment consists primarily of Praziquantel with or without steroids and anti-seizure medication if indicated. Follow-up is by both clinical and radiological assessment.
 ...
PMID:Cerebral cysticercosis: a case report with particular reference to recent advances in diagnosis and treatment. 347 48

Cerebral cysticercosis is a parasitic infestation with a highly variable prognosis and diverse clinical manifestations. Over the period of two years 51 patients were studied prospectively with this infestation, paying particular attention to the duration and severity of the illness, clinical course, CT findings and therapeutic modalities. Patients with parenchymal cysts or calcification without hydrocephalus had a benign disorder presenting commonly with seizures. This type of infestation usually is long-standing, almost never requires surgical treatment, responds to praziquantel therapy and has a good prognosis. In contrast, patients who present with hydrocephalus, large supratentorial cysts, multiple granulomata with cerebral oedema or with vasculitis and cerebral infarction, have an aggressive, acute or subacute illness, presenting with raised intracranial pressure, gait disturbances, mental changes, seizures, cranial nerve palsies, hemisphere syndromes, chronic meningitis and stroke. This malignant form usually requires surgical therapy, does not respond to praziquantel and may produce a fatal outcome or serious sequelae.
 ...
PMID:A prognostic classification of cerebral cysticercosis: therapeutic implications. 378 74

Cerebral cysticercosis is the result of infestation of the brain with the larval stage of the intestinal tape worm Taenia Solium. The disease, endemic in some parts of the world, especially Mexico, South America, India, Eastern Europe, is still encountered practically all over the world. There appear to be distinct geographical variations not only in the incidence but also the pattern of the disease. The commonly accepted modes of infection do not stand a critical analysis of available epidemiological data. The brain is a site of predilection for this infestation, where it results in meningeal racemose, parenchymatous ventricular or mixed types of lesions. It may thus produce meningo-encephalitis, granulomatous meningitis, ependymitis , focal granulomas, solitary or multiple parenchymatous cysts, hydrocephalus or a combination of these. Clinically its manifestations are protean and often perplexing, consisting, either alone or in combination, of raised intracranial pressure, focal or multifocal or generalized epileptic seizures, signs and symptoms of a focal mass lesion, hydrocephalus or chronic meningo-encephalitis. Important features of the disease are remissions and recurrences. Laboratory diagnostic investigations are generally unrewarding, there being so far, no single completely reliable test. Recent CAT scan studies have been helpful but not always diagnostic. There is no known medical treatment. Excision of a solitary parenchymatous or intraventricular lesion provides gratifying results but the management of diffuse lesions, presenting with raised intracranial pressure ("pseudo-tumour") is often frustrating. Extensive bilateral decompression, with or without an additional thecoperitoneal shunt, is helpful in some of these cases.
 ...
PMID:Cerebral cysticercosis. 637 90

We reviewed the clinical features, diagnosis, and treatment in 127 cases of cysticercosis cerebri. The chief syndromes were seizures (55.1%), hydrocephalus (37.8%), and stroke (11.8%). Serum or CSF indirect hemagglutination titers, determined in 101 patients, were positive in 84.1% of those with CSF pleocytosis but in only 42.1% of those without. Computed tomography (CT), employed in 85 patients, showed typical multiple calcifications in 64.7%. The CT scans were most useful in the surgical treatment of ventriculomeningeal infestation. Ventricular shunt implantation was performed in 40 patients with hydrocephalus and produced marked improvement in 32. Cyst resection was necessary only for patients with rapidly enlarging fourth ventricle cysts.
 ...
PMID:Cysticercosis cerebri. Review of 127 cases. 711 41

Scabies is a common infestation for patients of all ages throughout the world. One of the standard therapies for scabies is 1% lindane lotion. Lindane has been associated with neurotoxic reactions, specifically seizures. We describe a case of a middle-aged adult man with human immunodeficiency virus (HIV) infection who was found to have typical scabies and was treated with a single topical application of lindane. Two hours after the application, the patient experienced a new-onset generalized seizure. We believe that the triad of HIV infection, medications that reduce seizure thresholds, and percutaneous absorption factors, in the aggregate, induced the seizure. We believe that lindane should not be prescribed for patients with HIV infection.
 ...
PMID:Neurotoxic reaction to lindane in an HIV-seropositive patient. An old medication's new problem. 753 5

The cysticercosis is an infestation caused from the larva of Taenia solium, which is demoniated Cysticercus cellulosae. Infestation by the encysted forms occur within brain, muscle, cutis, eye and more rarely within kidney, liver, thyroid. The cysties cause inflammation, oedema and residual calcification. In the SNC they are responsible for seizures, usually of focal type, hydrocephalus, meningitis, endocranic hypertension, stroke. One case of neurocysticercosis in a 15 years old boy is described: the clinical pictures, the neuroradiologic images and the treatment are discussed.
 ...
PMID:[Neurocysticercosis: a rare cause of convulsive crises]. 866 97

The authors present 27 cases of cerebral hydatid cyst (CHCy) treated between 1980 and 1992. These cases of CHCy represent 2.8% of all cases of expansive nontraumatic lesions in children. Most of the patients were between 6 and 10 years of age. There was a substantial prevalence of male patients-18 cases (66.6%). Most of the children with CHCy were from rural areas. The cysts were all located in the cerebral hemispheres (none in the posterior fossa). Usually two or three lobes were affected and the cysts were most often retrorolandic. Only 8 patients (29.6%) also had pulmonary or hepatic infestation. All patients were operated on immediately the diagnosis was established. Operative mortality was very low (1 patient died immediately after surgery). There have been 11 cases of recurrence; all these patients have been reoperated on. Neurological sequelae were mainly partial and general seizures. Epilepsy developed postoperatively in five patients. Paresis, which usually disappears in time, was the most common motor disturbance. Two other important postoperative complications were subdural effusion and ventricular dilatation (six cases). There have been five cases of multiple recurrences (four of these patients have since died). Treatment with albendazole was used in three cases without significant results.
 ...
PMID:Cerebral hydatid cyst in children. Experience of 27 cases. 875 Sep 49


1 2 3 4 Next >>