Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036572 (seizures)
80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Triphasic waves are usually thought of as indicating a metabolic encephalopathy. Recent investigations have added nonmetabolic etiologies to the differential diagnosis of triphasic waves. Seizures are not generally thought of as associated with triphasic waves. Similarities in the appearance of records with encephalopathies and continuous triphasic waves and those of some patients with the Lennox-Gastaut syndrome have been noted. We presented a case which suggests that the presence of TW in a patient with a metabolic encephalopathy might suggest petit mal status epilepticus.
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PMID:Triphasic waves and spike wave stupor. 158 47

Petit mal status epilepticus was induced by high doses of thyroxine, confirming experimental evidence that thyroxine may lower the seizure threshold. This is another hazard of rapidly correcting the hypothyroid state.
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PMID:Thyroxine-induced petit mal status epilepticus. 393 79

Two known epileptics presented with abnormal behaviour. One was inattentive, aggressive and ataxic. The other carried out quite complex, though purposeless activity. EEG's revealed that the patients' behavioural abnormalities were due to uncontrolled seizures. Absence Status is an uncommon condition and its various manifestations can lead to delays in its recognition and treatment. It should be considered as a possible diagnosis in any patient who presents with recurring episodes of confusion.
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PMID:Absence status: a report of two cases. 643 57

A case report is presented here. A 33-year-old female who had been medicated with Chinese medicine showed a typical psychomotor status which conformed to all items of Heintel's and Treiman and Delgado-Escueta's diagnostic criteria of psychomotor status. When she was 33 years old in the 34th week of pregnancy on April 11, 1981, she was found to be in an epileptic twilight state during which a delirious state and some automatisms were observed. As the incidence of automatisms gradually increased, she was finally seized with a typical psychomotor status in which automatisms were quite periodically and frequently repeated without complete recovery of consciousness between seizures. This status still continued despite an intravenous injection of diazepam and phenytoin and barely ceased with the medication of clonazepam and carbamazepine four days after the beginning of the status.
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PMID:Psychomotor status--a female case in the 34th week of pregnancy. 654 12

Status epilepticus is a condition in which multiple epileptic seizures occur without complete recovery from the physiological effects of one seizure before another seizure occurs. There are as many types of SE as there are kinds of epileptic seizures. Generalized convulsive status epilepticus initially presents with repeated generalized convulsions without full recovery of consciousness between seizures. If untreated or undertreated, the convulsive activity becomes progressively subtle and is accompanied by a predictable series of progressive EEG changes. Non-convulsive SE refers to complex partial SE or absence SE, both of which exhibit an epileptic twilight state of altered contact with the environment. In simple partial SE there is no impairment of consciousness, and the behavioural changes reflect focal ictal discharges confined to one area of the cortex. There are between 65,000 and 150,000 cases of the SE in the US each year. Both acute and remote cerebral insults can cause SE, as can severe systemic disease that causes SE secondary to a toxic-metabolic encephalopathy. Mortality is high, but is largely a reflection of underlying aetiology when SE is treated appropriately and aggressively. Treatment is focused on terminating ongoing seizure activity as quickly as possible, both because the longer SE persists the more likely permanent neuronal damage will ensure and also because of strong evidence that the longer SE persists the more refractory to treatment it will be. Currently the most commonly accepted treatment protocol involves rapid initiation of therapy with intravenous lorazepam (0.1 mg/kg), followed, if necessary, by 20 mg/kg of phenytoin, followed, if necessary, by 20 mg/kg of phenobarbital. However, some neurologists still use intravenous diazepam (because of its more rapid antistatus effect) followed by phenytoin. New experimental data in the rat suggest that phenytoin followed by diazepam may be more effective, but this order of administration still has to tested in properly designed clinical trials.
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PMID:Status epilepticus. 906 83