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Query: UMLS:C0036572 (seizures)
 80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Castleman's disease is a rare, benign lymphoproliferative disorder that usually arises in lymph nodes, most commonly in the mediastinum. The authors report the clinical and pathological features of three patients with localized Castleman's disease of the leptomeninges. There were two women, aged 63 and 82 years, and one 25-year-old man. Two patients had progressive focal motor seizures of 3 and 24 months' duration, and the third patient presented acutely with generalized seizures. The clinical diagnosis was meningioma in each case, based on computerized tomography scans, cerebral arteriography, and the operative findings. All three lesions arose in the leptomeninges, compressed the underlying cerebral cortex, and infiltrated the overlying dura to a variable extent. Surgical excision of the tumor resulted in marked clinical improvement in all three patients. Histologically, two cases were classified as the hyaline-vascular type and one as the plasma cell type. Immunohistochemical stains of the latter case revealed a monoclonal population of mature plasma cells. Only a few scattered polyclonal plasma cells were seen in the other two cases. The authors conclude that Castleman's disease involving the leptomeninges is a rare disorder that may mimic meningioma clinically and radiographically.
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PMID:Castleman's disease of the leptomeninges. Report of three cases. 339 72

A case of intracranial foreign body granuloma is reported which was caused by cotton pledgets after total removal of meningioma. A 46 year-old woman was admitted on July 10, 1982, complaining of generalized convulsive seizures. CT and cerebral angiography revealed a left falx meningioma. The meningioma was totally removed under the left frontoparietal osteoplastic craniotomy. Microscopical findings were meningotheliomatous meningioma without malignancy. Despite the total removal, she developed two attacks of convulsion. Cerebral CT revealed a slightly high density mass with contrast-enhancement where the meningioma had been removed. Re-operation was performed on July 16, 1983. There was a granuloma with cotton fibers surrounded by yellow capsule without residual or recurrent meningioma. Only two cases have ever been reported in the literature so far reviewed. The differential diagnosis of foreign body granuloma is discussed and it is stressed to pay attention not to leave cotton pledgets during operations.
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PMID:[A case of foreign body granuloma caused by cotton pledgets that remained during intracranial operation]. 360 Sep 86

The patient was a 24-year-old male who was admitted to the Dept. of Neurosurgery of Miyazaki Medical College in April of 1982 with a history of generalized convulsive seizures. Neurological examination on admission revealed slight mental disturbance, bilateral marked papilloedema and homonymous right upper quadrantanopsia. Plain skull X-ray films showed a destructive change of the bone in the left sphenoid ridge and sella floor. CT scan showed a huge mass of slightly high density in the left anterior and middle fossae with a marked enhancement with contrast media. It was fed mainly by the left anterior and middle cerebral arteries and partly by the left middle meningeal artery on angiogram. The tumor was considered to be a type of malignant meningioma originating from the left sphenoid ridge. Total removal of the tumor without any morbidity was thought to be difficult because of its size, hypervascularity and location. From clinical and radiological features, this tumor was thought to be an angioblastic meningioma of hemangiopericytoma type and to be radiosensitive. Cobalt-60 irradiation to the tumor was attempted with a total dose of 49 Gy for over a period of 6 weeks. CT scan performed at the stage of 23 Gy-irradiation showed high radiosensitivity of the tumor and CT scan two weeks after the completion of irradiation showed a marked reduction of its volume to one third. The patient became free from headache and memory disturbance after radiotherapy. On the forty eighth day after completion of the irradiation, the tumor was totally removed with ease and minimal bleeding.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Radiosensitive meningioma--report of a case]. 370 50

Our study covered a 5-year period, and included all patients within a well-defined area who developed seizures after age 60 years. The dominant cause of seizures was a previous stroke, accounting for 32% of all cases. Tumors accounted for 14%, and the cause of seizures remained unknown in 25%. Seizures were recurrent in greater than 80% of patients with first seizure greater than 6 months after stroke. Fifteen of 21 patients with tumors had metastatic tumors. Of the six patients with primary brain tumors, five had malignant gliomas and one had a meningioma. We conclude that epilepsy with onset after age 60 years is more often symptomatic than is epilepsy in younger patients; since seizures were the first sign of a central nervous system (CNS) disease in half of the patients with brain tumors, careful investigation is necessary to reach a correct diagnosis.
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PMID:Etiology of seizures in the elderly. 372 Jul 6

Paranasal meningiomas were diagnosed in ten dogs based on gross and light microscopic examinations of tissue specimens, and, in one case, electron microscopic examination. Seven of ten dogs were female (average age was 13 years). Most dogs (7/10) had seizures on examination. Two dogs with meningioma located in the nasal cavity had nasal discharge, and one had epistaxis. Tumors originated in the nasoparanasal region (eight) and frontal region of the cranial cavity (two). The histologic types of meningioma included psammomatous (two), transitional (three), meningotheliomatous (two), fibroblastic (two), and angioblastic (one). Tumors were malignant and extended to the brain in eight cases. These tumors differed from intracranial meningiomas mainly in their more anaplastic nature and aggressive behavior.
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PMID:Paranasal meningioma in the dog: a clinicopathologic study of ten cases. 375 Jul 29

Thirty-four patients (20 female and 14 male) were admitted to a neurological department between 1974 and 1983 with intracranial meningioma. The mean age was 56.9 years. The patient material was divided in two groups, one with dementia (11 patients) and one without (23 patients). The most frequent symptom leading to admission was mental deterioration in the dementia group and epileptic seizures in the other group. The location of the tumours was similar in both groups. In all patients with dementia a combination of history, neurological examination and electroencephalogram clearly indicated a focal brain lesion.
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PMID:How shall we investigate dementia to exclude intracranial meningiomas as cause? An analysis of 34 patients with meningiomas. 395 28

A chondrosarcoma arising from the falx cerebri in a 15-year-old boy is reported. The patient had been suffering from convulsive seizures and weakness of the limbs on the left side for about 7 months prior to admission. A high-density mass attached to the falx was demonstrated by computed tomographic scan. Clinically it was very similar to a falx meningioma, and the final diagnosis was obtained from histopathological examination. The tumor was completely excised at operation, which is extremely important to prevent both local recurrence and distant metastasis.
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PMID:Chondrosarcoma arising from the falx cerebri. 396 67

Angiographically occult arteriovenous malformations not associated with clinically recognizable intracranial hemorrhage appear to be rare. We are reporting three cases of histologically proven arteriovenous malformations of the brain that were angiographically occult. These cases presented with seizures or attacks of dizziness, and were detected by computed tomography scan, radionuclide scan, or both. The preoperative diagnosis was granuloma in the first case and meningioma in the other two. After surgical exploration, biopsy revealed an arteriovenous malformation in each case. A review of 47 cases in the literature is tabulated and etiologies of the angiographically occult arteriovenous malformations are discussed. The routine use of computed tomography scan and timely, appropriate surgical intervention with the operating microscope for the removal of these deeply situated lesions is necessary for the diagnosis and therapy.
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PMID:Angiographically occult arteriovenous malformations. 397 39

A patient with episodes of transient global amnesia and transient partial amnesia was found to have a meningioma impinging on the right medial temporal lobe. Multiple partial complex seizures and EEG abnormalities suggested an epileptogenic disorder.
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PMID:Transient global amnesia and meningioma. 399 Sep 76

Differences in function between the cerebral hemispheres are well documented for normal subjects and, in diseased states, these are used to lateralize and localize a dysfunction. However, the difference in frequency of occurrence of left vs. right hemisphere lesions and the greater likelihood of epilepsy occurring on the left have received scant attention. In the present study patients with a diagnosis of meningioma or cerebral abscess were identified from the EEG computer file. After operation the meningioma patients with predominantly left-sided tumours showed a statistically significant greater chance of developing seizures, similarly those with left-sided cerebral abscess. Considering a larger group of patients with temporal lobe epilepsy from a variety of causes, a left-sided EEG focus occurred more frequently - and was statistically significant - than a right-sided or bilateral disturbance. The full explanation of these results is not clear but they suggest that the hemispheres function differently in patients with a cerebral disorder like epilepsy, as is known to be the case in normal subjects.
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PMID:Left and right cerebral hemisphere differences in the occurrence of epilepsy. 401 23


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