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Query: UMLS:C0036572 (seizures)
 80,221 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The adverse reactions from aqueous myelography in 88 primates were reviewed to determine what factors increase the risk of complications. Seventy-four iocarmate (Dimeray) myelograms were obtained on 41 animals, and 90 metrizamide (Amipaque) myelograms were obtained on 47 animals. The risk of seizures and death from iocarmate myelography was higher than from metrizamide myelography. In animals that had previous myelograms or showed evidence of arachnoiditis, the risk of complications from aqueous myelography was higher. Additional precautions may be indicated if aqueous myelography is performed in patients with arachnoiditis.
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PMID:Risk factors in complications of aqueous myelography. 9 91

The effect of hydration on the incidence of complications from myelography with aqueous media was studied. Myelography was performed with methylglucamine iocarmate in dehydrated and vigorously hydrated monkeys. The incidence of seizures and the severity of arachnoiditis were significantly greater in the dehydrated animals. The authors suggest that patients be permitted fluids ad lib. prior to myelography with aqueous media, or in some cases be given fluids intravenously.
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PMID:The effect of hydration on the acute and chronic complications of aqueous myelography. An experimental study. 10 31

Metrizamide is a nonionic water-soluble contrast medium for neuroradiological studies that is less irritating to the nervous system than other water-soluble agents. Studies in adults have shown that metrizamide has advantages over currently available media, but experience with children has been limited. Sixty-two children have had myelography or ventriculography using metrizamide. The children ranged in age from 11 days to 22 years. Technically satisfactory studies were obtained in every patient. No major complications were encountered. Minor side-effects included headache in 11 children (18%), mild nausea or vomiting in 16 children (26%), and fever in 4 children (6%). Seizures did not occur. One infant in the study subsequently died of unrelated problems; there was no evidence of arachnoiditis at postmortem examination. Metrizamide is a safe, effective contrast medium for neuroradiological use in children.
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PMID:Clinical evaluation of metrizamide for neuroradiology in chilren. 31 Feb 77

Electroroentgenography was used for the first time in neurological practice in 70 patients. Indications for its use were brain tumors, intracranial hematomas, epileptical seizures and a necessity to define inflammatory, traumatical changes and brain tumors. These studies permitted to depict hydrocephaly, basal and convexital arachnoiditis, asymmetrical ascites, local dilatation of the third ventricule, a dislocation and deformation of the ventricules in tumors and intracranial hematomas, sequalae of closed brain injuries. It was also proved that the use of electroroentgenography is leasible and has advantages in the evaluation of the CSF system.
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PMID:[Use of electroroentgenography in air contrast studies of the brain]. 121 Sep 37

Clinical, biochemical and electroencephalographic examinations were carried out in 96 children with the post-traumatic convulsive syndrome. The time of the development of convulsive syndrome and its clinical manifestations are reviewed. In 75 children, convulsive attacks took the course of traumatic arachnoiditis; in 21 children, the clinical picture of the disease with consideration for the characteristics and frequency of convulsive seizures and changes in the character of the children was suggestive of epilepsy development. Possible pathogenetic mechanisms of the development of convulsive attacks in children who have had a closed craniocerebral injury are analyzed.
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PMID:[Clinical, biochemical and electroencephalographic findings in children with a post-traumatic convulsive syndrome]. 643 69

Pneumoencephalographic examinations (after endolumbar injection of 60 ml of air) were carried out in 84 patients who developed epileptic seizures after closed brain injuries. In all the patients diffuse cysto-adhesive arachnoiditis, open inner hydrocephalus, and delayed resorption of air from the cerebral ventricles were revealed roentgenologically. A therapeutic effect that manifested itself in a subjective improvement, abatement of the organic signs, cessation, diminution on the frequency, or transformation of the seizures into milder ones was noted in 77% of the patients. Data on vegetative reactions and changes of the brain bioelectrical activity under the influence of the pneumoencephalography are presented. Possible role of those changes in the mechanisms of the pneumoencephalography therapeutic action is discussed.
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PMID:[Pneumoencephalography in the diagnosis and complex treatment of traumatic epilepsy]. 679 58

The results of the initial North American trial of the nonionic, water-soluble contrast medium iopamidol for lumbosacral myelography are reported. The iopamidol was easily visualized by fluoroscopy during introduction, and the radiographic quality of all 12 conventional myelographic examinations was excellent. The diagnoses were herniated nucleus pulposus (seven), traumatic dislocation (one), metastasis (one), and normal (three). One patient had a repeat myelogram with a different hydrosoluble contrast medium 2 months after his iopamidol examination and surgery and showed no radiographic evidence of arachnoiditis. The adverse reactions were all mild and transient: headache (four cases), nausea (two), and leg pain (one). There were no diaphoresis, fever, seizures, hallucinations, agitation, or vital sign changes. Electrocardiography, hematology, and blood chemistries were all normal. In two patients, electroencephalogram changes, three to four bursts of diffuse intermittent rhythmic delta activity with no spiking, were present at 6 hr with return to normal at 24 hr.
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PMID:Clinical trial of iopamidol for lumbosacral myelography. 680 Feb 40

Water-soluble contrast media, which have been employed in the examination of the lumbar spinal canal for 30 years, can sometimes result in severe complications, such as arachnoiditis, epileptic seizures, and myoclonic spasm. These complications have been seen less frequently since the advent of metrizamide, a new non-ionic water-soluble contrast medium. However, a further neurological complication has now arisen--mental disorder, varying in kind and degree; for example, organic psychosis and perceptual disturbance. Some characteristic cases are described. A series of 75 patients, all of whom received varying amounts of metrizamide for the purpose of cervical, thoracic and lumbar myelography, has been studied. Seven patients were found to have a pronounced organic psychosis and three patients had visual illusions or hallucinations. It is suggested that there is some degree of correlation between the total amount of iodine received and patient age. By careful enquiry and examination, similar disturbances were also found some 4-8 h after myelography with other water-soluble contrast media.
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PMID:Mental disorders after myelography with metrizamide and other water-soluble contrast media. 738 36

The aminoacid content of cerebrospinal fluid (CSF) was studied in 51 patients with the epileptic syndrome in conjunction with tumors and cerebral arachnoiditis. In general epileptical seizures CSF demonstrated the highest glutamine content. A drop in the glutamine concentration was seen in hydrocephalus, in rare general and focal seizures. The epileptic syndrome is characterized by an increase in CSF of cystidin, thyrosine and methionine. More pronounced changes in aminoacid metabolism were detected in the epileptic syndrome, in chronic inflammatory brain disorders.
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PMID:[Amino acid composition of cerebrospinal fluid in the epilepsy syndrome]. 741 7

Cysticercosis is the most frequent parasitic disease of the central nervous system in the world and is endemic in such developing countries as Mexico. There is insufficient information about neurocysticercosis in children. The purpose of this study was to collect information on the main social factors associated with neurocysticercosis, the clinical picture, diagnosis and treatment, and the final outcome in 122 Mexican children. The ages of the patients ranged from 14 months to 17 years, with a mean of 8 years; 51 male (41.8%) and 71 female (51.8%) patients were seen; half of these patients (61) lived in well-urbanized areas; the parents of 77 families (57.3%) had only an elementary school grade average, and 46 (37.7%) lived in close proximity to animals. The most common features were seizures, intracranial hypertension and learning disabilities. The diagnosis of neurocysticercosis was supported by computed tomography or magnetic resonance imaging studies and cerebrospinal fluid analysis. The treatment was varied, with anti-convulsives, steroids, and albendazole, and only 8 patients underwent ventriculo-peritoneal shunts for hydrocephalus. The follow-up ranged from 6 months to 5 years; 90 patients became asymptomatic; 6 developed refractory epilepsy; 14, learning disabilities; and 10, a chronic type of the disease with repeated episodes of intracranial hypertension; 2 died because of chronic arachnoiditis.
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PMID:Neurocysticercosis in children. Clinical experience in 122 patients. 945 78


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