Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0036421 (
PSS
)
10,989
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PSS
2978
collagen
811
Sep
717
ACS
457
hole
282
PAH
280
cytokine
253
She
187
Mol
158
HLA
132
Poly
121
IL-6
108
topoisomerase I
107
CREST
97
CD4
93
interferon
87
ankylosing spondylitis
86
RNP
85
endothelin-1
76
rheumatoid factor
74
endothelin receptor
73
fibronectin
67
type I collagen
66
IL-4
64
IFN
62
ANA
62
ACR
60
tumor necrosis factor
60
connective tissue growth factor
60
phosphodiesterase
58
TGF-beta
58
RNA polymerase I
58
transforming growth factor-beta
57
C-reactive protein
56
chemokine
55
TNF
55
calcium channel
53
CD8
52
vascular endothelial growth factor
51
interleukin-6
51
AFM
49
autoantigen
48
smooth muscle actin
47
IgA
46
lymphoid
46
SSA
46
insulin
45
IL-10
44
Pol
44
IL-13
44
gut
42
ribonucleoprotein
41
CD19
40
IL-1
39
SMA
38
platelet-derived growth factor
38
myeloperoxidase
37
histone
37
HLA-DR
36
CD34
35
von Willebrand factor
35
serum albumin
35
fibrillin
34
hemoglobin
33
IL-17
33
major histocompatibility complex
33
polypeptide
32
tyrosine kinase
31
PDGF
31
SSB
30
U1-70K
30
interferon-gamma
30
ACE
30
IL-8
30
collagenase
30
glycoprotein
29
renin
29
NMR
29
MRI
28
vascular endothelium
28
more...
Disease
PSS
10989
PSS
2978
PSS
2978
scleroderma
2079
systemic lupus erythematosus
1500
rheumatoid arthritis
1073
Raynaud's phenomenon
780
connective tissue disease
696
autoimmune disease
653
hypertension
492
interstitial lung disease
473
dermatomyositis
445
arthritis
433
mixed connective tissue disease
371
pulmonary hypertension
352
polymyositis
320
cancer
319
lupus
313
Raynaud
308
pulmonary fibrosis
301
vasculitis
268
CREST
208
lupus
208
calcinosis
195
diffuse scleroderma
185
localized scleroderma
180
sclerodactyly
177
morphea
159
myositis
158
multiple sclerosis
153
idiopathic pulmonary fibrosis
148
vascular disease
144
SLE
134
lung disease
128
diabetes
120
telangiectasia
120
psoriasis
117
cold
116
interstitial pneumonia
116
sarcoidosis
116
renal failure
115
ischemia
114
primary biliary cirrhosis
113
dysphagia
113
Sjogren's syndrome
111
graft-versus-host disease
106
tumor
101
antiphospholipid syndrome
94
gastroesophageal reflux disease
93
atherosclerosis
93
ankylosing spondylitis
89
renal disease
83
depression
83
esophageal dysmotility
81
systemic disease
80
Pulmonary arterial hypertension
79
heart failure
77
glomerulonephritis
72
Esophageal
71
psoriatic arthritis
71
fasciitis
70
skin disease
69
rheumatism
69
osteoarthritis
63
Crohn's disease
62
gangrene
62
rare disease
62
thrombocytopenia
61
eosinophilia
60
silicosis
59
collagen disease
57
myopathy
56
Best
56
pneumonia
55
SEM
54
collagen disease
53
PAA
52
proteinuria
52
anemia
51
xerostomia
50
more...
Symptom
pain
185
dyspnea
136
arthralgia
76
weakness
68
fatigue
60
myalgia
45
diarrhea
44
erythema
35
nausea
32
cough
31
headache
30
constipation
27
heartburn
26
exertional dyspnea
25
chest pain
25
discomfort
24
collapse
24
vomiting
22
anesthesia
20
discomfort
19
abdominal pain
19
dry eye
18
thinning
17
acidity
15
seizures
13
hemoptysis
13
regurgitation
12
spasm
12
shortness of breath
11
numbness
11
bloating
11
splenomegaly
11
respiratory distress
11
pallor
9
cyanosis
9
angina
9
syncope
9
Ill
8
flushing
8
vertigo
8
livedo
7
hypothermia
6
asthenia
6
oliguria
6
paresthesia
6
Gastrointestinal symptoms
6
cachexia
6
exhaustion
5
dysarthria
5
Skin thickening
5
overweight
5
dry skin
5
back pain
5
clubbing
5
tinnitus
4
hypoproteinemia
4
insomnia
4
functional recovery
4
sleepiness
4
hepatosplenomegaly
4
Lower urinary tract symptoms
4
Depressive symptoms
4
cerebellar ataxia
4
analgesia
4
anorexia
3
urinary frequency
3
tremor
3
ataxia
3
leg edema
3
joint stiffness
3
hoarseness
3
dizziness
3
polymyalgia
3
Urinary symptoms
3
hemiplegia
3
starvation
3
polyuria
3
skin damage
3
HSA
3
dysuria
2
more...
Drug
Dermatol
758
ZnO
48
lysine
39
Cardiovasc
34
Bosentan
29
Bosentan
29
IL-2
27
Iloprost
25
IFN-gamma
24
CTX
24
TiO2
17
ETA
16
SiO2
13
ROC
13
Silica
12
Rituximab
12
caffeine
12
Imatinib
11
Prednisolone
11
vitamin E
10
Asthma
9
Gel
8
nitroglycerin
7
CSF
7
ROS
7
Tocilizumab
7
Cisapride
6
G-CSF
6
Gleevec
6
Paraffin
6
Nitric Oxide
6
ascorbate
5
CaCl2
5
Nephron
5
CaCl2
5
Dial
5
Spectrum
5
CaCl2
5
NH3
5
lactose
5
THF
5
NADH
5
Histamine
5
Prednisone
4
p75
4
Captopril
4
MAP
4
CCL
4
PFT
4
NOV
4
ABC
4
ACT
4
Treprostinil
4
Methylprednisolone
4
Nephron
4
BLM
3
Fluorescein
3
uPA
3
Acacia
3
Fluorescein
3
Infliximab
3
DPA
3
Infliximab
3
Omeprazole
3
Fraction
3
Pirfenidone
3
PTH
3
TAT
3
Retinoic acid
2
RbCl
2
Dasatinib
2
Antithymocyte globulin
2
RbCl
2
EML
2
Angiotensin II
2
PDGF B-chain
2
Gastro
2
PDL
2
CMX
2
Abatacept
2
more...
Enzyme
ACS
457
PAH
280
RNA polymerase
80
peroxidase
65
phosphodiesterase
59
ACE
57
topoisomerase
52
topoisomerase
50
collagenase
49
ERK
35
focal adhesion kinase
33
mitogen-activated protein kinase
33
renin
29
thrombin
23
lysozyme
22
superoxide dismutase
22
glucose oxidase
22
type III procollagen
20
creatine kinase
20
alkaline phosphatase
20
trypsin
18
reverse transcriptase
16
PCE
15
RNase
14
guanylate cyclase
14
catalase
13
RNase
12
BAL
12
urokinase-type plasminogen activator
12
hyaluronidase
12
protein kinase C
12
tissue plasminogen activator
11
PDE
10
plasmin
10
MIP
10
beta-galactosidase
10
protein kinase
9
NO synthase
9
lactate dehydrogenase
9
proteasome
9
elastase
8
chondroitinase
7
chondroitinase
7
luciferase
7
hyaluronidase
7
ribonuclease
7
ribonuclease
7
prostate-specific antigen
7
MMP-3
6
caspase-3
6
NADPH oxidase
6
pepsin
6
interstitial collagenase
6
acetylcholinesterase
6
acid phosphatase
6
thromboplastin
6
NADPH oxidase
6
thyroid peroxidase
6
SCS
5
lipase
5
urease
5
phospholipase C
5
pyruvate dehydrogenase
5
lipoxygenase
5
DNase
5
matrix metalloproteinase 9
5
urease
5
glutathione S-transferase
5
Alternating
5
calcineurin
5
transcriptase
5
MMP
4
matrix metalloproteinase 2
4
beta-glucuronidase
4
ceruloplasmin
4
caspase-1
4
proteinase-3
4
MEK
4
APC
4
laccase
4
more...
Compound
Clin
1296
Dec
789
sodium
515
ACS
457
ACS
457
water
388
DNA
306
PAH
280
salt
199
calcium
187
oxygen
179
tin
161
CO2
144
silicon
117
silver
103
prostacyclin
88
sulfate
77
nitric oxide
73
hydrogen
72
PEG
72
acetate
70
butyric acid
68
butyric acid
68
butyric acid
68
phosphate
66
PEI
65
PEI
65
ammonium
63
glucose
62
ANA
62
ANA
62
Cardiol
60
PEG
59
vinyl
56
TNF
55
creatinine
55
copper
54
PAA
52
bromide
50
acrylic acid
45
tyrosine
43
zinc
42
thiophene
41
ethanol
41
lysine
41
iron
39
DMSO
39
nitrogen
38
Collagen
38
iodine
37
aluminum
36
potassium
36
arginine
36
ANCA
35
proline
33
barium
33
vitamin D
31
methanol
31
tryptophan
30
tryptophan
30
tryptophan
29
His
29
tryptophan
29
titanium
25
CTX
24
SiO2
24
TEM
23
serine
23
nickel
22
fluorine
22
hyaluronic acid
21
isopropanol
20
benzene
20
nitrate
19
phosphorus
19
Nifedipine
18
NH2
17
carbonate
17
prostaglandin E1
17
molybdenum
17
more...