Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036421 (PSS)
10,989 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
prostaglandin I2 (prostacyclin) receptor 11.5
PSS 11.5
SAMD3 10.5
Kelch-like protein 7 10.5
HLA-DQB1 chain 10.5
PM-Scl 10.2
OCTD 9.9
ODF3B 9.9
NAG-2 9.9
platelet receptor for type III collagen 9.9
p25beta 9.5
C8orf13 9.5
CHST13 9.5
Kelch-like protein 12 9.5
Phospholipase D4 9.3
CREST 9.3
PEM2 9.2
PSD3 9.2
OTUD6B 9.2
cornea-derived transcript 6 9.2
PXK 9.1
CD247 9.0
UDP-D-xylose:core protein xylosyltransferase 8.9
VII-5 8.9
IL1R3 8.9
ZBTB3 8.9
UTP14A 8.9
SNAP1 8.9
LRP2BP 8.7
B2GPI 8.7
POLR1B 8.7
SCHIP1 8.6
TREH 8.5
IGFL2 8.5
SSR4 8.5
U1-70K 8.4
U11/U12 8.4
IFIX 8.3
PS21 8.2
CD11A 8.2
more...
Disease
Nonspecific esophageal motility disorder 11.5
Lung involvement in systemic sclerosis 11.5
Idiopathic (IPAH) 11.5
Hollow visceral myopathy 11.5
syndrome; cervical 11.5
Autoimmune skin disease 11.5
PSS 11.5
PSS 11.5
PSS 11.5
Systemic sclerosis sine scleroderma 11.3
Scleroderma renal crisis 11.2
Limited cutaneous systemic sclerosis 10.9
Pseudoscleroderma 10.9
renal scleroderma 10.7
diffuse scleroderma 10.7
Juvenile scleroderma 10.5
Secondary Raynaud's phenomenon 10.5
Acute intestinal pseudo-obstruction 10.5
Alezzandrini syndrome 10.5
Sinus node fibrosis 10.5
sclerodactyly 10.5
scleroderma 10.0
Focal vasculitis 9.9
CHCL 9.9
Sarcoid myopathy 9.9
OCTD 9.9
oropharyngeal disorder 9.9
Diffuse infiltrative lung disease 9.9
localized scleroderma 9.9
CREST 9.7
Raynaud's phenomenon 9.7
mixed connective tissue disease 9.7
EGMA 9.6
Generalized morphea 9.5
Disorders of pigmentation 9.5
Diffuse pulmonary fibrosis 9.5
Familial visceral myopathy 9.5
CRST syndrome 9.4
Skin induration 9.3
morphea 9.3
more...
Symptom
Red face 10.5
Skin thickening 9.4
Auspitz's sign 9.2
Subungual hyperkeratosis 8.7
Retrosternal pain 7.5
skin impairment 7.0
vaginal discomfort 7.0
Urinary symptoms 6.8
ischuria 6.8
S3 gallop 6.4
reproductive problem 6.4
polymyalgia 6.2
musculoskeletal impairment 6.1
Lower urinary tract symptoms 6.0
cardiovascular impairment 5.7
Organ failure 5.5
painful swallowing 5.5
Skin symptoms 5.4
Signs and Symptoms 5.4
skin pain 5.3
heartburn 5.2
Overlying 5.1
peau d'orange 5.0
arthralgia 4.9
trigeminy 4.9
generalized abdominal pain 4.9
Gastrointestinal symptoms 4.9
generalized pain 4.9
Buckling 4.9
Musculoskeletal symptoms 4.8
astasia 4.6
livedo 4.6
facial droop 4.5
exertional dyspnea 4.4
prostatism 4.3
dry eye 4.3
myalgia 4.3
bloating 4.3
menometrorrhagia 4.2
acid regurgitation 4.1
more...
Drug
Sarpogrelate hydrochloride 8.8
Potaba 8.3
Bosentan 7.6
Bosentan 7.6
Iloprost 7.1
Treprostinil 7.1
Minipress 6.4
Olopatadine hydrochloride 6.4
Sodium metabisulfite 6.0
Panorex 6.0
Activase 5.9
NOV 5.8
Beraprost 5.7
CMX 5.7
Cisapride 5.7
Tocilizumab 5.6
Antithymocyte globulin 5.5
Beraprost sodium 5.5
Tween 85 5.4
Cilengitide 5.3
TMX 5.2
Pirfenidone 5.2
Omniscan 5.1
EML 5.1
PDGF B-chain 5.0
Muse 5.0
InCl3 5.0
Bosutinib 4.9
Abatacept 4.9
Sodium benzoate 4.9
BLyS 4.8
Sodium citrate 4.7
Sodium citrate 4.7
PFT 4.6
TFT 4.5
RbCl 4.4
RbCl 4.4
Prednisolone 4.4
PNT 4.4
Omniscan 4.4
more...
Enzyme
EC 2.4.2.16 11.5
EC 2.4.2.26 8.1
PAH 7.5
glycuronidase 7.0
type III procollagen 6.4
arylsulfate sulfotransferase 6.1
tryptophan aminotransferase 6.1
phosphatidylserine synthase 5.5
galactosylhydroxylysyl glucosyltransferase 5.1
proteinase-3 5.1
PCE 5.1
phosphatidylglycerophosphate synthase 4.8
prolyl-tRNA synthetase 4.8
pantetheinase 4.7
Escherichia coli exonuclease III 4.6
DSR 4.6
interstitial collagenase 4.2
BAL 4.1
NMT 4.1
ACS 4.1
topoisomerase 4.0
GD3 synthase 4.0
histidyl-tRNA synthetase 3.9
topoisomerase 3.9
SCS 3.8
SPS 3.8
lysophospholipase D 3.7
PRT 3.7
PPH 3.6
glucose oxidase 3.6
PHT 3.6
lysyl hydroxylase 3.5
thiopurine methyltransferase 3.4
chondroitinase 3.3
IMP dehydrogenase 3.3
chondroitinase 3.2
Alternating 3.2
phosphodiesterase 3.2
ACE 3.2
MsrA 3.1
more...
Compound
NMVA 10.5
C16H20N2O3 10.5
CI 301 9.9
dichloroacetic anhydride 9.9
Motretinide 9.5
IQ 1 9.2
1,1,1-trifluoro-2,4-pentanedione 8.9
4-dodecylbenzenesulfonic acid 8.7
4-dodecylbenzenesulfonic acid 8.7
4-dodecylbenzenesulfonic acid 8.7
4-dodecylbenzenesulfonic acid 8.7
4-dodecylbenzenesulfonic acid 8.5
Didodecyldimethylammonium bromide 8.3
Sinomenine hydrochloride 8.2
3-thiophenecarboxylic acid 8.0
Pyromellitic dianhydride 7.8
PAH 7.5
Rubrene 7.4
MEMA 7.3
9,9-dimethyl-9,10-dihydroacridine 7.3
9,9-dimethyl-9,10-dihydroacridine 7.3
Ciprofloxacin hydrochloride 7.0
2,4,6-triphenyl-1,3,5-triazine 6.9
BVE 6.8
11-aminoundecanoic acid 6.8
CFN 6.7
HAQ 6.7
Tamibarotene 6.6
Ciprofloxacin hydrochloride 6.6
Minipress 6.4
Levcromakalim 6.3
Norethisterone acetate 6.3
Novex 6.2
Magnesium hydroxide 6.1
Tosylate 6.1
2,3-dichlorophenol 6.0
2,1,3-benzothiadiazole 6.0
Berbamine 6.0
3-amino-1-propanol 6.0
ETN 5.9
more...