Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036421 (PSS)
10,989 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PSS 2978
collagen 811
Sep 717
ACS 457
hole 282
PAH 280
cytokine 253
She 187
Mol 158
HLA 132
Poly 121
IL-6 108
topoisomerase I 107
CREST 97
CD4 93
interferon 87
ankylosing spondylitis 86
RNP 85
endothelin-1 76
rheumatoid factor 74
endothelin receptor 73
fibronectin 67
type I collagen 66
IL-4 64
IFN 62
ANA 62
connective tissue growth factor 60
ACR 60
tumor necrosis factor 60
RNA polymerase I 58
phosphodiesterase 58
TGF-beta 58
transforming growth factor-beta 57
C-reactive protein 56
TNF 55
chemokine 55
calcium channel 53
CD8 52
interleukin-6 51
vascular endothelial growth factor 51
more...
Disease
PSS 10989
PSS 2978
PSS 2978
scleroderma 2079
systemic lupus erythematosus 1500
rheumatoid arthritis 1073
Raynaud's phenomenon 780
connective tissue disease 696
autoimmune disease 653
hypertension 492
interstitial lung disease 473
dermatomyositis 445
arthritis 433
mixed connective tissue disease 371
pulmonary hypertension 352
polymyositis 320
cancer 319
lupus 313
Raynaud 308
pulmonary fibrosis 301
vasculitis 268
lupus 208
CREST 208
calcinosis 195
diffuse scleroderma 185
localized scleroderma 180
sclerodactyly 177
morphea 159
myositis 158
multiple sclerosis 153
idiopathic pulmonary fibrosis 148
vascular disease 144
SLE 134
lung disease 128
telangiectasia 120
diabetes 120
psoriasis 117
interstitial pneumonia 116
sarcoidosis 116
cold 116
more...
Symptom
pain 185
dyspnea 136
arthralgia 76
weakness 68
fatigue 60
myalgia 45
diarrhea 44
erythema 35
nausea 32
cough 31
headache 30
constipation 27
heartburn 26
chest pain 25
exertional dyspnea 25
collapse 24
discomfort 24
vomiting 22
anesthesia 20
abdominal pain 19
discomfort 19
dry eye 18
thinning 17
acidity 15
seizures 13
hemoptysis 13
regurgitation 12
spasm 12
respiratory distress 11
bloating 11
shortness of breath 11
numbness 11
splenomegaly 11
angina 9
cyanosis 9
syncope 9
pallor 9
Ill 8
vertigo 8
flushing 8
more...
Drug
Dermatol 758
ZnO 48
lysine 39
Cardiovasc 34
Bosentan 29
Bosentan 29
IL-2 27
Iloprost 25
CTX 24
IFN-gamma 24
TiO2 17
ETA 16
ROC 13
SiO2 13
caffeine 12
Rituximab 12
Silica 12
Prednisolone 11
Imatinib 11
vitamin E 10
Asthma 9
Gel 8
Tocilizumab 7
ROS 7
CSF 7
nitroglycerin 7
G-CSF 6
Gleevec 6
Cisapride 6
Paraffin 6
Nitric Oxide 6
CaCl2 5
Histamine 5
Dial 5
THF 5
Spectrum 5
Nephron 5
NH3 5
CaCl2 5
CaCl2 5
more...
Enzyme
ACS 457
PAH 280
RNA polymerase 80
peroxidase 65
phosphodiesterase 59
ACE 57
topoisomerase 52
topoisomerase 50
collagenase 49
ERK 35
mitogen-activated protein kinase 33
focal adhesion kinase 33
renin 29
thrombin 23
glucose oxidase 22
superoxide dismutase 22
lysozyme 22
type III procollagen 20
alkaline phosphatase 20
creatine kinase 20
trypsin 18
reverse transcriptase 16
PCE 15
guanylate cyclase 14
RNase 14
catalase 13
protein kinase C 12
BAL 12
urokinase-type plasminogen activator 12
RNase 12
hyaluronidase 12
tissue plasminogen activator 11
beta-galactosidase 10
plasmin 10
PDE 10
MIP 10
NO synthase 9
protein kinase 9
lactate dehydrogenase 9
proteasome 9
more...
Compound
Clin 1296
Dec 789
sodium 515
ACS 457
ACS 457
water 388
DNA 306
PAH 280
salt 199
calcium 187
oxygen 179
tin 161
CO2 144
silicon 117
silver 103
prostacyclin 88
sulfate 77
nitric oxide 73
PEG 72
hydrogen 72
acetate 70
butyric acid 68
butyric acid 68
butyric acid 68
phosphate 66
PEI 65
PEI 65
ammonium 63
glucose 62
ANA 62
ANA 62
Cardiol 60
PEG 59
vinyl 56
creatinine 55
TNF 55
copper 54
PAA 52
bromide 50
acrylic acid 45
more...