Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036341 (schizophrenia)
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Human Gene/Protein
5-hydroxytryptamine (serotonin) receptor 2A 9.0
PAGE2B 9.0
FAM174B 9.0
DEAD-box protein p72 9.0
C1orf110 9.0
transmembrane protein 108 9.0
alpha-7 nicotinic cholinergic receptor subunit 9.0
zinc finger protein 323 9.0
DDTL 9.0
FLJ30058 9.0
triple LIM domain protein 9.0
MSTP131 9.0
transcription factor DLX1 9.0
DRD5P2 9.0
KLHDC3 9.0
OR6C65 9.0
DRD5P1 9.0
KBTBD3 9.0
calcium channel, voltage-dependent, beta 2 subunit 9.0
zinc finger with KRAB and SCAN domains 4 9.0
SP3 protein 9.0
PCDHA8 9.0
Smg-6 homolog, nonsense mediated mRNA decay factor 9.0
RIMS2 protein 9.0
contactin associated protein-like 4 9.0
BRD1 protein 9.0
GOLGA8A 9.0
ATPase type 13A4 9.0
C11orf87 9.0
DKFZp761B107 9.0
DDX26B 9.0
GLUR7 9.0
C15orf59 9.0
SCZD9 9.0
Bromodomain containing 1 9.0
t-SNARE domain containing 1 9.0
malic enzyme 3, NADP(+)-dependent, mitochondrial 9.0
Nxph1 9.0
KIAA1751 9.0
DGSC 9.0
PTD015 9.0
TSNARE1 9.0
Astrotactin-2 9.0
Homer 1 variant 9.0
C14orf39 9.0
CSMD3 protein 9.0
ZNF718 9.0
ZNF804A protein 9.0
MRDS1 9.0
pyridoxal-dependent decarboxylase domain containing 1 9.0
LDL-PLA2 9.0
MYT1L protein 9.0
chromosome 6 open reading frame 106 9.0
ZDHHC8 protein 9.0
C6orf217 9.0
WDR88 9.0
SCZD4 9.0
nuclear RNA export factor 5 9.0
unc-51-like kinase 4 9.0
SP4 protein 9.0
LRRC4B 9.0
cholinergic receptor, nicotinic, alpha polypeptide 2 9.0
glutamate receptor, ionotropic, delta 1 9.0
EFCAB5 9.0
eukaryotic translation initiation factor 4 gamma, 3 9.0
kynurenine aminotransferase III 9.0
unc-13 homolog B 9.0
protein phosphatase 1E 9.0
PCDHGA8 9.0
OGFOD2 9.0
DISC1 protein 8.9
ZNF804A 8.8
LG72 8.8
dysbindin 8.8
D-amino acid oxidase activator 8.8
Dysbindin 8.8
DTNBP1 8.8
DAOA 8.7
Synaptotagmin XI 8.6
ARL6IP4 8.6
more...
Disease
Affective blunting 9.0
cenesthopathic schizophrenia 9.0
presenile psychosis 9.0
cyclic schizophrenia 9.0
Thought broadcast 9.0
SCZD4 9.0
Intelligence reduced 9.0
bouffee delirante 9.0
Factitious cheilitis 9.0
Receptive language disorder 9.0
Catatonic phenomena 9.0
SCZD12 9.0
Nonorganic insomnia 9.0
Drug-induced obesity 9.0
Delusional perception 9.0
Anxiety Disorders of Childhood or Adolescence 9.0
Chronic psychosis 9.0
Amaurotic idiocy 9.0
mixed schizophrenia 9.0
KZ syndrome 9.0
schizophrenia 9.0
Thought insertion 9.0
Non-organic sleep disorders 9.0
acute paranoid reaction 9.0
Jumping from height 9.0
psychomotor symptom 9.0
Acute and transient psychotic disorders 8.8
schizoaffective disorder 8.7
prodromal schizophrenia 8.7
Formal thought disorder 8.7
early onset schizophrenia 8.7
Schizotypal disorder 8.6
prenatal nutritional deficiency 8.6
Schizophreniform Disorder 8.6
latent schizophrenia 8.6
loosening of associations 8.5
Impaired insight 8.5
Homicidal ideation 8.5
Psychiatric Hospitalization 8.5
Acute schizophrenia 8.5
Late paraphrenia 8.5
senile psychosis 8.5
chronic schizophrenia 8.4
schizotypal personality disorder 8.4
Lack of insight 8.3
Hyperprolinemia type I 8.3
borderline schizophrenia 8.3
schizophreniform psychosis 8.3
undifferentiated schizophrenia 8.3
psychogenic psychosis 8.3
hebephrenia 8.3
flat affect 8.2
Periodic catatonia 8.2
affective psychosis 8.2
residual schizophrenia 8.2
Schizophrenia and other psychotic disorders 8.2
delusions of reference 8.2
blunted affect 8.2
SCZD1 8.0
DFNB47 8.0
Motor Skills Disorders 8.0
Delusions of infestation 8.0
Hallgren's syndrome 8.0
explosive personality disorder 8.0
Poverty of speech 8.0
eponychia 8.0
Primary polydipsia 8.0
Schizophrenia and related disorders 8.0
Paroxysmal perceptual alteration 8.0
involutional paranoia 8.0
mysophobia 8.0
Functional hallucinations 8.0
Granular ependymitis 8.0
Cycloid psychoses 8.0
Pseudohallucinations 8.0
childhood schizophrenia 8.0
Ideas of reference 8.0
Hysterical psychosis 8.0
acute schizophrenic episode 8.0
paranoid state 8.0
more...
Symptom
referral to nursing home 9.0
Constricted affect 9.0
Exacerbation of anxiety 9.0
Positive and Negative Symptoms 8.6
Drug withdrawal symptoms 8.0
Fine tremor 8.0
auditory hallucination 8.0
Psychotic Symptoms 7.9
Extrapyramidal symptoms 7.7
Inappropriate affect 7.5
Posturing 7.5
waxy flexibility 7.4
Mannerisms 7.4
Olfactory hallucinations 7.3
catatonia 7.2
Prodrome 7.1
Involuntary Movement 7.0
hearing voices 6.9
change in bowel movements 6.2
Psychiatric symptoms 6.1
elevated mood 6.0
aprosodia 6.0
Tandem gait 5.7
emotional shock 5.5
startle reaction 5.4
Acute dystonia 5.2
Cognitive Symptoms 5.2
Hyposensitivity 5.2
Injection site pain 4.7
visual hallucination 4.7
Motor dysfunction 4.7
apathy 4.6
Circling 4.6
unable to sleep 4.5
polydipsia 4.4
Depressive symptoms 4.4
micropsia 4.3
hopelessness 4.3
delayed language development 4.2
stigma 4.2
General symptoms 4.2
feeling depressed 4.1
Convergence Insufficiency 4.0
hyperosmia 3.9
breast hyperplasia 3.9
lassitude 3.9
polyopia 3.9
disturbed balance 3.8
impaired motor coordination 3.8
feeling tired 3.8
agitation 3.7
insomnia 3.6
Decreased activity 3.6
Signs and Symptoms 3.5
alexithymia 3.5
forgetfulness 3.3
despair 3.3
muscle rigidity 3.2
hypersomnia 3.2
enuresis 3.1
personality change 3.1
Fatigability 3.1
dystonia 3.1
Urge incontinence 3.0
motor symptom 3.0
Subjective tinnitus 2.9
sleepiness 2.9
situational stress 2.7
Behavioral symptoms 2.7
tonic-clonic seizure 2.7
partial seizure 2.6
fasciculation 2.6
Sedation 2.6
clumsiness 2.5
chorea 2.5
jaw pain 2.5
Poor sleep 2.5
consciousness disturbance 2.5
Crawling 2.5
Opposition 2.4
more...
Drug
Zatosetron maleate 9.0
Mazapertine succinate 9.0
Lurasidone hydrochloride 9.0
Bromperidol decanoate 9.0
Paliperidone palmitate 8.8
Geodon 8.7
Olanzapine pamoate 8.6
Geodon 8.6
Paliperidone 8.5
Blonanserin 8.5
Org 24448 8.5
Iloperidone 8.2
Asenapine maleate 8.2
Bifeprunox 8.0
Nozinan 8.0
Risperdal Consta 7.9
Seroquel 7.8
Clozaril 7.8
Pipotiazine palmitate 7.5
Ziprasidone hydrochloride 7.5
Haloperidol decanoate 7.3
Setoperone 7.2
Zuclopenthixol 7.1
Molindone hydrochloride 7.0
Ceronapril 7.0
Ocaperidone 7.0
Zotepine 7.0
Repetin 6.9
Pipamperone 6.7
MDL 11939 6.7
Inversine 6.7
Bromperidol 6.6
Remoxipride 6.5
Cloperastine 6.5
Clopenthixol 6.5
PCP 6.2
Doral 6.2
Nalfurafine hydrochloride 6.2
Inversine 6.0
Penfluridol 6.0
Timiperone 5.9
Klonopin 5.9
Perphenazine 5.8
Oxypertine 5.7
Clothiapine 5.7
Mirapex 5.6
Fluphenazine 5.6
Lipoic Acid 5.5
Cytomel 5.3
Cytomel 5.2
Uncaria hook 5.2
fluphenazine dihydrochloride 5.2
Akineton 5.0
Ritanserin 5.0
Tranxene 5.0
Buspar 5.0
Dizocilpine maleate 5.0
Indiplon 4.9
Dapiprazole 4.9
Bextra 4.9
Avanafil 4.9
Pyridoxamine 4.9
Tranxene 4.8
Fosamprenavir 4.8
Flupenthixol 4.8
Zydis 4.7
Myo-Inositol 4.7
Thioridazine 4.7
Mellaril 4.7
Modafinil 4.5
Fluvoxamine maleate 4.5
Bretazenil 4.5
Ceruletide 4.5
Terguride 4.5
Remeron 4.5
Tofisopam 4.5
Reboxetine 4.4
Medicon 4.4
Fluspirilene 4.4
Buspar 4.3
more...
Enzyme
chitobiosyldiphosphodolichol beta-mannosyltransferase 8.0
serine racemase 6.5
PCP 6.2
proline dehydrogenase 6.1
kynurenine aminotransferase 5.3
arsenite methyltransferase 5.2
NPL 5.2
SRR 5.1
D-aspartate oxidase 5.1
D-amino-acid oxidase 5.0
catechol O-methyltransferase 5.0
kynurenine 3-monooxygenase 4.8
Lod 4.6
AFR 4.4
TMT 4.4
SDMT 4.3
proline oxidase 4.3
HK3 4.2
gamma-glutamyl phosphate reductase 4.0
neuropsin 4.0
HCS 4.0
aspartylglucosaminidase 3.8
neuropsin 3.7
DAT 3.7
methylenetetrahydrofolate reductase 3.7
fucokinase 3.7
methylenetetrahydrofolate reductase 3.7
kynurenine formamidase 3.7
memapsin 2 3.6
tryptophan hydroxylase 3.5
kynureninase 3.5
CPT 3.5
PdxH 3.3
TUT 3.3
CPT 3.3
isoprene synthase 3.3
glucose-fructose oxidoreductase 3.3
GMP reductase 3.3
KAT 3.3
aspartate racemase 3.2
GAS 3.1
glutamate decarboxylase 3.1
dopamine beta-hydroxylase 3.1
PME 3.1
nardilysin 3.1
calpain 10 3.0
TRS 3.0
CFI 3.0
monoamine oxidase 3.0
palmitoyl-protein thioesterase 3.0
prolyl endopeptidase 3.0
PIP kinase 3.0
indoleamine 2,3-dioxygenase 3.0
CPT 3.0
dihydropyrimidinase 2.9
porphobilinogen deaminase 2.9
GSK 2.9
tyrosine hydroxylase 2.8
aromatic L-amino acid decarboxylase 2.8
NMT 2.7
KAR 2.7
histamine N-methyltransferase 2.5
neurolysin 2.5
SST 2.5
DOPA decarboxylase 2.5
N-acetylglucosaminyltransferase III 2.5
NQO2 2.4
monoacylglycerol lipase 2.4
quinolinic acid phosphoribosyltransferase 2.4
GRK5 2.4
prostate-specific membrane antigen 2.4
adenosine kinase 2.3
glutaminase 2.3
glutaminyl cyclase 2.3
Protein 2 2.3
MsrA 2.3
inositol phosphatase 2.2
phosphatidylethanolamine N-methyltransferase 2.2
methionine adenosyltransferase 2.2
GABA transaminase 2.2
more...
Compound
C30H34O13 9.0
Sertindole 8.0
9-iodophenanthrene 8.0
[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 8.0
Ziprasidone 7.9
Clozapine 7.9
Aripiprazole 7.8
Olanzapine 7.7
C14H12FN3O 7.5
2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 7.5
R 31 7.5
Quetiapine 7.4
Loxapine 7.3
Phencyclidine 7.2
C4H6N2O2 7.0
C4H6N2O2 7.0
Butyrophenone 7.0
C4H6N2O2 7.0
C4H6N2O2 7.0
C4H6N2O2 7.0
C4H6N2O2 7.0
C4H6N2O2 7.0
C4H6N2O2 7.0
Risperidone 7.0
C4H6N2O2 6.7
Alstonine 6.7
C4H6N2O2 6.7
4-chlorobenzamide 6.7
Levomepromazine 6.6
MHPG-sulfate 6.5
Xanomeline 6.4
Nemonapride 6.3
OMCA 6.3
C4H6N2O2 6.2
Fluphenazine decanoate 6.2
C4H6N2O2 6.2
Clopenthixol 6.1
ethanesulfonamide 6.1
C4H6N2O2 6.0
Previtamin D3 6.0
DCPM 6.0
3-fluorobenzaldehyde 6.0
Pimaric acid 6.0
Metyrosine 6.0
Altanserin 6.0
PCP 6.0
Procyclidine 6.0
2-methylbenzamide 5.9
Kryptopyrrole 5.9
Haloperidol 5.8
Sultopride 5.8
Biperiden 5.8
1-azabicyclo[2.2.2]oct-3-yl 5.8
Noveril 5.7
Fluperlapine 5.7
C4H6N2O2 5.7
3-cyanoalanine 5.7
DSM 5.7
Kynurenic acid 5.7
Haloperidol 5.7
Psilocybin 5.6
TDT 5.6
Cuprizone 5.6
Showdomycin 5.6
3-hydroxybenzamide 5.6
Fluphenazine 5.6
yohimban 5.6
Ethyl diazoacetate 5.6
Geissoschizine 5.6
Dihydrouracil 5.6
D-Serine 5.5
Lanthionine ketimine 5.5
MK801 5.5
1,3-benzoxazol-2(3H)-one 5.3
Allysine 5.3
1-propylpiperidine 5.2
Sarcosine 5.2
NAAG 5.2
Ketamine 5.2
3-hydroxypregnan-20-one 5.2
more...