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Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a consecutive series of 227 psychiatric hospital admissions, data were recorded in respect of the complaint of pain. Eighty-six (38%) had pain. Fourty-four (19%) mentioned it spontaneously and 49 (22%) had no relevant physical cause. Women were affected more often than men (P less than 0.01) and tended to complain more often of severe pain (P less than 0.01). Severe pain was more often reported spontaneously (P less than 0.02). Also, the longer pain lasted the more likely the patient was to report it spontaneously (P less than 0.02). Men more often had a relevant physical diagnosis (P less than 0.05) and the low back was the commonest site of pain in them. Pain was relatively often associated with diagnoses of anxiety and personality disorder and relatively infrequently with schizophrenia, organic brain syndromes and transient situational disturbances. It is concluded that whilst there is a strong association between pain and psychiatric illness, this is less prominent, paradoxically, in some of the more severe psychiatric disturbances.
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PMID:Significance of pain in psychiatric hospital patients. 64

Gender differences have been reported for a variety of clinical measures in patients with schizophrenia. Clinical characterization may be helpful in identifying symptom clusters which can then be linked to underlying brain function. In this study 74 men and 33 women meeting DSM-IIIR criteria for schizophrenia were studied off medication and rated on measures of symptom type and severity, as well as premorbid and current function. Men were more severely impaired in ratings of negative symptoms, while positive symptoms were not significantly different. There were also differences in premorbid and current functioning, with women manifesting better social functioning than men.
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PMID:Gender differences in the clinical expression of schizophrenia. 139 Apr 1

Over a period of 3 years, 340 patients (199 men and 141 women) who met DSM-III-R criteria for schizophrenia and who knew their exact date of birth were interviewed to determine the age at onset of illness. The immediate family's first awareness of psychotic symptoms was used as the index of onset. Men had a significantly earlier mean age at onset (24 +/- 6) than the women (27 +/- 8). By the time they were 30 years of age, 83% of the men and 66% of the women had become ill. The findings are remarkably similar to those of an earlier report in the same cultural setting, and add to the evidence of sex differences in age at onset of schizophrenia.
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PMID:Age at onset in a cohort of schizophrenics in Nigeria. 148 21

227 first-contact schizophrenic patients (DSM-III) were followed-up for 2 years. The psychiatric teams responsible for the treatment of the patients conducted a detailed, standardized interview with the patients at entry and during the follow-up. Men showed a poorer premorbid heterosexual development and they also tended to be more withdrawn than women. Following the onset of the illness, men still failed to establish satisfactory heterosexual relationships, they suffered more often from negative symptoms, and they displayed poorer working capacity and functional ability than women. At the beginning of the follow-up men had a more pessimistic view of the development of their life situation over the next 2 years, a prediction which turned out to be correct. The predictions made by the psychiatric teams were very similar. In their plans for treatment the psychiatric teams recommended primarily psychotherapeutic methods for female patients--and women actually went to psychotherapy more often than men--whereas it was felt that the rehabilitation of men should concentrate on working capacity and basic social skills. The poorer psychosocial outcome of men seems to be due to their poor premorbid development--specifically heterosexual development--and negative symptoms. Together, these factors form a particularly harmful combination from the point of view of the social role of men in our society. The treatment system seems to be unable to adequately respond to the specific needs of men suffering from schizophrenia.
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PMID:Gender and short-term outcome in schizophrenia. 228 39

The content and structure of delusions were compared in 30 women and 30 age-matched men with Schizophrenic Disorder. Men showed an excess of homosexual persecutory delusions and of grandiose delusions involving social status and personal power. Women showed an excess of delusions of fertility and of jealousy, and were more often than men objects rather than subjects in their grandiose delusions. There was an excess of women who reported co-objects of persecution, and who personally knew their persecutors, nearly always men. These differences mirrored aspects of the social environment, especially with regard to sex-role stereotyping.
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PMID:Sex differences in the phenomenology of schizophrenic disorder. 292 49

The expression of schizophrenia was examined in 169 DSM-III diagnosed schizophrenics. Restricted maximum likelihood factor analysis was used to test the invariance of the hypothesized symptom model across gender. Findings indicated that schizophrenic women not only expressed more impulsivity and affective symptomatology than did men, but their psychotic symptoms covaried consistently with the expression of impulsivity, anger and other affective symptomatology. Men's expression of schizophrenia covaried positively with withdrawal/isolation and an inability to function, suggesting a possible negative symptom pattern. Gender differences were not attributable to misclassification, differences in diagnostic subtypes, nor to selection. Results are discussed in light of their implications for understanding the heterogeneity of schizophrenia.
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PMID:Gender and the expression of schizophrenia. 340 82

Nursing homes have played a major role in deinstitutionalization, and their increased use for the mentally ill has been questioned. We performed a controlled study of nursing homes as an alternative to continued psychiatric hospitalization. Men (N = 403) referred for nursing home placement from eight Veterans Administration medical centers were randomly assigned to community nursing homes (CNHs), Veterans Administration nursing care units, continued care on the same ward, or transfer to another psychiatric ward. Patients met defined criteria for schizophrenia or organic brain disease. Data were collected before random assignment and six and 12 months later, covering physical and mental function, psychopathology, mood, social adjustment, satisfaction with care, as well as drug use, characteristics of settings, and movement in and out of settings. Significant differences between settings were found in self-care, behavioral deterioration, mental confusion, depression, and satisfaction with care. Results were strikingly consistent, showing the group transferred to another ward doing better and the CNH group doing worse. Drug use did not differ from six months before entering the study or later between the settings. Cost showed a marked advantage for the CNH group. Thus, the less costly community nursing home alternative must be viewed in the context of the nonmonetary costs of less favorable patient outcome.
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PMID:Nursing home care as an alternative to psychiatric hospitalization. A Veterans Administration cooperative study. 406 10

The interrelationships among gender, premorbid functioning, and negative symptoms were examined in a first-admission inpatient sample with DSM-III-R schizophrenia. Fifty-two subjects were assessed with the Schedule for the Assessment of Negative Symptoms (SANS) at baseline and 6-month follow-up. Three indicators of premorbid functioning were examined: the Premorbid Adjustment Scale, the Quick Test, and the GAF for the best month in the year prior to the baseline interview. Men and women had relatively similar ratings on each of the 5 SANS global subscales at both times; they were also relatively similar on most of the indicators of premorbid functioning. The men and women were categorized into low vs moderate-high negative symptom groups at baseline, and no differences in premorbid functioning were detected. When the sample was classified into those with and without consistent negative symptoms at baseline and 6-month follow-up, the enduring negative men and women had significantly poorer premorbid functioning in several areas than the consistently non-negative patients. Our findings support the importance of assessing negative symptoms longitudinally and suggest that gender is not strongly associated with negative symptoms and premorbid functioning in patients ascertained at early stages of schizophrenia.
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PMID:Gender, premorbid characteristics and negative symptoms in schizophrenia. 748 93

Gender differences in diagnosis, demographic and family characteristics, and trauma histories among psychiatric outpatients at a Veterans Affairs clinic were examined. Among the 51 women and 46 men, significantly more women had affective disorders and schizoaffective disorder; significantly more men had anxiety disorders, schizophrenia, and substance use disorders. Although women had sharply higher rates than men of every type of trauma except combat trauma, more male veterans received a diagnosis of posttraumatic stress disorder. Men were four times more likely to be married. Women were more likely than men to be the sole caretakers of minor children. These differences have important treatment and policy implications. The findings confirm that recently initiated VA programs recognize important treatment needs of female veterans.
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PMID:Mental health care needs of female veterans. 868 82

Using case register data, the overall marital rate among 5158 patients with mental illness was found to be comparable to the general population. The proportion of those ever married was markedly reduced in the schizophrenic group relative to those with a manic or neurotic illness. Men with schizophrenia had a particularly low rate of marriage. The overall marital fertility of the 3 groups was comparable to each other and appeared to be higher than that in the general population. In the schizophrenic group only, married men, particularly those with a family history of mental disorder, produced more children than married women. Men might represent a more fertile group of schizophrenic patients with some biological advantage of increased fecundity, which may help to compensate for negative selection pressures.
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PMID:Reproductive behaviour in schizophrenia relative to other mental disorders: evidence for increased fertility in men despite decreased marital rate. 762 1


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