Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0036341 (
schizophrenia
)
60,220
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The activity of
Phenylethanolamine
-N-Methyltransferase (PNMT) was assayed in 12 brain structures in a group of 8 chronic psychotics, a sub-group of 5 schizophrenics and a group of 7 normal controls. It was found significant decreased in substantia perforata posterior and nucleus accumbens. These two structures belong to the meso-limbic system. These data, therefore, suggest an inhibition of PNMT and/or an alteration of putative adrenergic neurons in the meso-limbic system, in
schizophrenia
.
...
PMID:[Possible alteration of adrenergic neurons in the mesolimbic system of psychotics (author's transl)]. 731 34
