Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0036341 (
schizophrenia
)
60,220
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Clorazepate dipotassium
(
Tranxene
), benzodiazepine of retarded anxiety-relieving, sedative and sleep-inducing action was used in an open sample of 36 patients for fast control of anxiety and aggression in the course of
schizophrenia
, schizoaffective psychosis and other psychotic disorders. The intensity of aggressive behaviors was assessed as 6-7 items on the CGI scale. After intramuscular injection of clorazepate complementing the so-called basic treatment in the mean daily dose of 150 mg, several hours lasting sedative effect was achieved. No unfavourable interactions between the applied clorazepate (
Tranxene
) and the other medicines applied simultaneously (mostly neuroleptics and antidepressant drugs) were observed. Clorazepate (
Tranxene
) is an effective and safe drug giving fast and long-lasting sedation of the patients with low risk of interaction with other drugs or of side-effects.
...
PMID:[The use of chlorazepate dipotassium (Tranxene) in the states of restlessness and agitation]. 951 7
