Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors have examined all of the hospitalized patients who were over sixty years old in all psychiatric clinics in Gifu Prefecture, Japan, on December 31, 1968, and many of them were reexamined on June 30, 1973. Through these both serial examinations, the following results are obtained: 1) Of the total 187 patients who underwent the first examination, 62 patients were still hospitalized and subjected to the second examination. 2) Twenty nine of the 62 patients were schizophrenics. One fourth of them were in remission, the rest being in a desolate or paraphrenic condition. Thirty six schizophrenics have discharged hospitals: 12 patients have left off hospitals getting a considerable improvement and 15 patients were dead. 3) Of the thirteen manic-depressives, only three were still hospitalized, and two of them were in remission. There were 10 discharged cases: three cases dead and six cases improved. 4) Six of the 24 patients diagnosed as senile dementia were still hospitalized. The diagnosis of two cases has been changed into paranoid reaction and depression respectively. Of 18 discharged patients, 14 cases were dead and the remaining four were improved. 5) Of the 22 patients diagnosed as senile psychosis, only two patients were still hospitalized, and the diagnosis has been changed into schizophrenia and epilepsy respectively. The 20 patients have left hospitals: nine cases dead and another nine improved. As the beginning symptoms, these patients showed paranoid-hallucinatic aspects which were similar to those of schizophrenia. In some cases, certain incidents that had preceded onset of the illness were found. 6) Most of the aged patients with the diagnoses associated with the physical conditions due to aging were dead.
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PMID:[Disease course and outcome in hospitalized patients over 60-years old]. 117 73

An investigation was made of all known cases of mental illness where more than one member of the family entered one of the Ontario Mental Hospitals. The materials is fairly complete for a period of 18 years. Analysis of the resulting data, on pairs of relatives, gave rise to the following conclusions of particular interest. (i) Schizophrenia, affective psychosis, senile psychosis, Huntington's chorea and mental defect are shown to be conditions which remain significantly true to type when mental disease occurs in different members of a family. As a rider to this, however, it is found that schizophrenia and affective psychosis are not very distinct entities and groups of closely related familial cases frequently include both diagnoses. (ii) Schizophrenia is a rare diagnosis in the fathers of patients and occurs in only 8.7% of fathers, as opposed to the 30.7% in the whole sample of relatives: it is not so rare in mothers (24.5%). (iii) The most frequent type of relationship in pairs of patients is sister and sister: next in frequency is the type brother and brother, then brother and sister. Mother and son, mother and daughter, father and daughter and then father and sone come next in order. Less frequent are uncle and nephew or uncle and niece and, again less frequent, aunt and nephew or niece; grandparents and grandchildren were rarely found. (iv) Fathers, diagnosed schizophrenic or first admitted below the age of 35, have more psychotic sons than psychotic daughters, but the reverse is true for mothers in the same categories. (v) Fathers diagnosed as having affective illness or first admitted at the age of 35 or over have more psychotic daughters than psychotic sons, but the reverse is true for mothers in the same categories. (vi) Male subjects with either schizophrenic or affective diagnosis and in early- or late-onset age groups, have more psychotic brothers than psychotic sisters. Similarly, female subjects have more psychotic sisters than psychotic brothers. (vii) Each main diagnosis group has its characteristic first admission age. (viii) The first admission age is earlier in males than in females for schizophrenics, and later in males than in females for affective disorders. (ix) Study of first admission ages in families indicates that parents and, particularly, grandparents are much older than children and, particularly, grandchildren at first admission. This effect is not attributed to progressive degeneration. (x) Male subjects show a significantly wider scatter of first admission ages than do female subjects.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:Survey of cases of familial mental illness. L. S. Penrose, July 1945. 183 62

The work analyses the results of treatment of acute surgical diseases and traumas of the abdominal organs in 84 patients 18 to 81 years of age suffering from various mental disorders. Schizophrenia was encountered in 47 patients, the manic-depressive syndrome in 16, epilepsy in 8, reactive psychosis in 8, and senile psychosis in 5 patients. Among 66 patients who were admitted for suspected acute surgical disease of the abdominal organs, in 54 the diagnosis was confirmed. Operation was conducted on 59 of them. Eighteen patients had an abdominal trauma. Fourteen patients were operated on for closed (2) and open (12) abdominal injury. All in all 73 patients were treated by operation. Eight patients died. The causes of death were peritonitis and intoxication (4), thromboembolism of the pulmonary artery (1), acute cardiovascular insufficiency (2), and pulmonary edema (1). The peculiarities of the diagnosis and postoperative management of these patients are discussed.
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PMID:[Acute surgical diseases and injuries of the abdominal organs in mentally ill patients]. 281 Nov 34

The psychic ill man, no matter the gravity of the syndrome presented, is not undesirable and does not constitute a contraindication in ocular surgery. But in these situations a correct evaluation of the general and ocular state must be done, and also a correct premedication, a local or general on case good-conducted anesthesia and a close cooperation with the psychiatrist. Are discussed the problems of the little psychiatry which appear in the ocular interventions: senile psychosis, unorganical psychoses like ambulatory schizophrenia, maniacal-depress psychosis and paranoia decompensated by surgical act.
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PMID:[Psychiatric aspects in eye surgery]. 833 30