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Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Comparisons were made between personality (MMPI) profiles of 26 part-time university students who scored in the upper and 29 students who scored in the lower one-quarter of the range on a scale that measures temporal-lobe signs in the normal population. Compared to the reference group, the subjects who displayed more temporal-lobe signs showed statistically significant elevations above a T score of 70 on Schizophrenia and Hypomania. There were secondary elevations on Psychasthenia and frequency scales. Similar profiles whose high-point scores display greater amplitude are typical for patients with schizotypal disorders and for many patients who have long histories of temporal lobe epilepsy. These results support the existence of a continuum of temporal-lobe lability that extends into the normal population.
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PMID:MMPI profiles of normal people who display frequent temporal-lobe signs. 362 13

The incidence of sexual contact with boys by women was found more prevalent than had been contended in the clinical literature. Male penitentiary inmates reported higher heterosexual contact as children than did college men. The effects upon the boy and his later adult sex life were generally reported as not traumatic, although coercion by the woman tended to be associated with a bad feeling about the experience at the time and a negative effect upon adult sex life. The majority of women were friends, neighbors, baby sitters, and strangers to the boy. Intercourse and genital touching were the predominant forms of sexual activity. Prison women who reported having such contact were significantly higher than the prison women who did not report contact on the Mini-Mult Schizophrenia and Hypomania scales and significantly lower on the Lie scale. Educational levels of the men and their parents were inversely associated with history of sexual contact.
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PMID:Parameters of sexual contact of boys with women. 368 6

The concept of 'sluggish schizophrenia' is virtually limited to the USSR and some other East European countries, and may contribute to the mis-diagnosis of democrats as psychiatric patients. Recently, a number of articles have appeared in the Soviet literature relating the diagnosis of 'sluggish schizophrenia' or 'slowly progressive schizophrenia' to affective disorders, especially hypomania. Soviet publications on this theme from 1980 to 1984 are discussed, together with their relationship to questions on the abuse of psychiatry.
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PMID:Political hazards in the diagnosis of 'sluggish schizophrenia'. 371 18

In a study of cases of recent onset of schizophrenia, schizophreniform psychosis and hypomania (DSM-III criteria), threatening life events were significantly related to the onset of schizophreniform psychosis but not schizophrenia. The results also suggest that threatening events may precipitate hypomanic episodes.
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PMID:Threatening life events in the onset of schizophrenia, schizophreniform psychosis and hypomania. 377 50

Slowly progressive schizophrenia with subclinical affective attacks in adolescence is characterized by undoubtful differences in the premorbid characteristics of patients, clinical picture and peculiarities of the course of the endogenic process. Different variants of the course are related to structurally and phenomenologically different variants of affective attacks. The more similar is the course of cyclothymia-like schizophrenia to protracted non-remission one, the more atypical are affective attacks (adynamic depressions and nonproductive hypomania); the more paroxysmal is the course, the more marked and diverse is the clinical picture of depression (dysphoric attacks) and the more typical are hypomanias. Patients with cyclothymia-like schizophrenia, besides therapy, are in need of the earliest possible rehabilitative treatment aimed at the continuation of education under easier conditions which expedites post-attack readaptation and improves social prognosis.
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PMID:[Characteristics of the course of cyclothymia-like schizophrenia in puberty]. 381 11

A representative sample of 908 hospital records covering admissions between 1920 and 1982 for depression was analyzed in order to assess the switch rate to hypomania/mania. The results are the following: (1) Over the decades of this century there has been a substantial increase in hospital admissions in Zurich for both depression and mania, but the ratio remained constant. (2) Due to this increase the clinicians can observe more spontaneous switches from depression to mania, which favors the assumption of a causal relationship when treatment is applied. (3) 64 of the 908 patients (7.0%) admitted for depression switched to hypomania or mania. Hypomania was observed in 48 cases (5.3%) and mania in 16 cases (1.7%). (4) The analysis of predisposing factors to a switch has resulted in a simple finding. Bipolar patients (including schizomanics) have an 8-fold higher switch rate (28.9%) than the unipolars (3.7%). The switchers are equally distributed over the two sexes and do not differ in the frequency of a family history of affective psychoses, schizophrenia, schizoaffective disorders, or suicide. (5) Bipolarity correlates positively with 'higher number of previous episodes', with 'readmitted' and with 'switch'. Therefore, studies selecting readmissions [Lewis and Winokur 1982] overrepresent switchers purposely. (6) A loglinear analysis together with some univariate strategies show that over the decades (from 1920 to 1982) there was no significant increase in switches of unipolar or bipolar patients. In conclusion, there is no evidence for a treatment-induced switch. This result is in line with Prien et al. [1973] and with Lewis and Winokur [1982].
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PMID:Switch from depression to mania--a record study over decades between 1920 and 1982. 405 86

The clinical presentation of three patients with meningiomas at different frontal sites is described. They had been ill for 3, 25, and 43 years before the tumour was demonstrated radiologically. Apathy, incontinence, dementia, and fits were seen in association with middle and superior frontal lesions, and may be mistaken for symptoms of involutional depression or presenile cerebral atrophy. In contrast, excitement and hallucinosis were seen in association with a basal frontal lesion, and may mimic psychotic syndromes like hypomania and schizophrenia, particularly if the tumour encroaches on the third ventricle and adjacent structures. Irreversible loss of myelin and axons in the frontal areas of brain surrounding the tumour may have contributed to the clinical picture of the syndrome shown by these patients.
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PMID:Three cases of frontal meningiomas presenting psychiatrically. 496 22

The mental state of 20 psychotic men with high urinary cannabinoid levels on admission to a psychiatric hospital was compared with that of 20 matched cannabis-free controls. All patients underwent toxicological analysis to exclude the presence of alcohol and other exogenous agents. Cannabis levels were measured by a semiquantitative enzyme immunological technique and mental state was assessed by the use of the Present State Examination (PSE), once shortly after admission and again 7 days later. The cannabis group showed significantly more hypomania and agitation and significantly less affective flattening, auditory hallucinations, incoherence of speech, and hysteria than did the controls. Clouding of consciousness was absent in most cannabis patients. After 1 week the cannabis group showed marked improvement (particularly in the psychotic syndromes), whereas the controls remained virtually unchanged. There was no significant difference in amount of medication received between the two groups. Our data suggest that a high intake of cannabis may be related to a rapidly resolving psychosis manifesting with marked hypomanic features, though often presenting as a schizophrenia-like illness.
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PMID:Cannabis-associated psychosis with hypomanic features. 612 63

The results of the study of 29 patients (25 boys and 4 girls) aged 4-11 years suffering from schizophrenia with manic disturbances are reviewed. These conditions were characterized by the absence of affect vitality, its homogeneity in the presence of emotional deficiency, dissociation of the manic syndrome, combination with autism, mental infantilism, superworship formations and neurosis-like disturbances. Four variants of chronic manias have been specified: benevolent, mischievous, hyperdynamic and hypomania with monotonous activity.
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PMID:[Protracted maniacal disorders in schizophrenic children]. 650 63

A total of 34 patients with the monopolar manic course of paroxysm-like schizophrenia were studied for their premorbid characteristics and the nature of their paroxysms, remissions and personality changes. The premorbid characteristics were consistent with the personality structure of schizoids or hyperthymic psychopaths. Two different types of manic paroxysms were specified: simple manic states whose symptomatology was determined mostly by affective disturbances and manic-delirious paroxysms manifested in the form of mania with acute sensual delusion and manic-paranoid conditions. Certain differences in the time-course of the disease were found to depend on the type of the manifest paroxysm. The author elucidated relatively unremarkable and slowly increasing personality changes and the good quality of remissions in cases with prolonged hypomania.
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PMID:[Schizophrenia with manic paroxysms during its course]. 673 Aug 22


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