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Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors discusses some unclear and insufficiently studied problems related to early infantile autism, regress of development and underdevelopment of schizophrenic children. The basis of early infantile autism is most likely a peculiar disturbance of development due to constitutional, organic and psychogenic factors. In most of the cases this syndrome is connected with the schizophrenic process. The majority of psychiatrists in the Soviet Union consider lowering to a more early level of development as a regress of development in child schizophrenia symptoms. The clinical picture of retarded development in childhood schizophrenia depends upon the age of the onset of the disease and the degree of progressiveness of the process. Depending upon these criteria it is possible to distinguish retarded development, resembling oligophrenia and phenomena of psychophysical infantilism.
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PMID:[Several developmental disorders in children with schizophrenia]. 6 1

Slowly progressive schizophrenia in children is marked in 45.5% of all the cases. This form of development usually cannotes a favourably developing variant of continuous and attack-like schizophrenia, characterized by a gradual increase of psychopath-like (schizoid) personality changes. For this reason it is necessary to differentiate the diagnosis of schizophrenia with the dynamics of psychopathy in children. The paper contains data of some criteria of a differential diagnosis of slowly progressive schizophrenia in relation to early childhood autism, psychic infantilism, obsessional neurosis, pathologically developing age crises and cyclothymia in children.
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PMID:[Differential diagnosis of slowly progressive schizophrenia in children]. 71 27

Psychogenias of the refusal reaction type observed in long-term stages of torpid schizophrenia in patients with marked negative changes and decreased fitness for work were subjected to clinical analysis. The results obtained suggest that such reactions are caused by the altered "background" in the form of distorted manifestations of psychic infantilism expressed here as a peculiar psychopathy-like defect of a "passively dependent personality disturbance" type. The study has made it possible to specify the psychopathologic structure of psychogenic states of the refusal reaction type which includes, apart from a characteristic psychogenic complex, anxiety depression in combination with signs of motor inhibition, as well as varying disturbances with refusal characteristics, attended by "evasive behaviour".
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PMID:[Psychogenias of the refusal reaction type in patients with slowly progressive schizophrenia]. 361 41

The results of the study of 29 patients (25 boys and 4 girls) aged 4-11 years suffering from schizophrenia with manic disturbances are reviewed. These conditions were characterized by the absence of affect vitality, its homogeneity in the presence of emotional deficiency, dissociation of the manic syndrome, combination with autism, mental infantilism, superworship formations and neurosis-like disturbances. Four variants of chronic manias have been specified: benevolent, mischievous, hyperdynamic and hypomania with monotonous activity.
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PMID:[Protracted maniacal disorders in schizophrenic children]. 650 63

43 children and adolescents, 27 boys and 16 girls aged 7 to 15, with the drive disorders syndrome were investigated. The diagnosis of schizophrenia was in 30 patients (the first group), residual organic brain damage in 13 (the second group). In the first group an onset of disease coincided with the first age crisis (3-4 years). Among the variants of the drive disorders such disorders as a runaway from home and wandering, that had irresistible and impulsive character were dominant. Near the puberty, the sexual and aggressive-sadistic drives prevailed. The drive disorders were accompanied with effective, neurotic-like and some other psychopathological symptoms. In the second group the first manifestations of the drive disorders coincided with the young school-age (7-9 years) period and these disorders occurred in the prepuberty (10-12 years) more frequently. The drives to the theft, runaway from home and wandering, aggression, increased sexual drive were dominant. The signs of psychic infantilism and immature emotional-will sphere come forward in the patients on this group. It was determined that inherited-constitutional as well as social factors are very significant for formation of the drive disorders syndrome.
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PMID:[The syndrome of drive pathology in children and adolescents (the age-related and nosological aspects)]. 928 Dec 75

54 patients, 24 men and 30 women, (mean age 27 years) were examined. Two types of obsessive-phobic disorders with the phenomena of mysophobia were distinguished: obsession of the external (extracorporal) threat and obsession of contamination. Disorders of the first type (25 cases) were observed in psychopathic-like schizophrenia. They were characterized by a fear of possible contacts with different pathogenic agents--toxic substances, sharp small subjects, bacteria. Obsessions presented with a system of actions preventing phobic situations (rituals). With progression of the disease there was a decrease of both the degree and affective saturation of phobic disorders together with preserving rituals. Negative disorders presented with rough psychopathic-like changes with features of the "verschroben" defect. The disorders of the second type (29 patients) were observed in neurosis-like schizophrenia. Mysophobia manifested with both the repeated control and the fear of contamination accomplished. Ritual behavior presented with repeated actions and repeated control of the "sterility" of the own body and the surrounding subjects. Dynamics of these disorders was characterized by a tendency to more severe rituals of the control and persisting anxiety. Deficit disorders manifested with mental infantilism with psychopathic-like disorders of schizo-anancastic sphere. The above types of the obsessive-phobic disorders have a differential-diagnostic significance in respect of clinical variations of schizophrenia and determination of the state acuity with possible reversibility of the disorders (in neurosis-like schizophrenia).
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PMID:[Obsessive-phobic disorders with the phenomena of mysophobia in slowly progressing schizophrenia]. 1124 27