Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nervous anorexia seen in males (25 cases), having a certain similarity in the clinical picture with female anorexia, has nevertheless, some special traits. Cases of anorexia in males are characterized by a higher predominance of hereditary loading, by an earlier onset (10--14 in comparison to 15--20 of female anorexia), a rather early appearance of refined deficitary symptomatology, and frequently enough a rapid psychopathization. However, these patients preserve formal abilities for a rather long period. The disease, as a rule, is an expression of a schizophrenic process unlike female anorexia, where this form of pathology may be inherent not only to schizophrenia but also to neuroses, psychopathy or be an independent psychosomatic disorder.
 ...
PMID:[Anorexia nervosa in men]. 51 74

Certain clinical observations cast doubt on the validity of the traditional psychological explanation of psychosomatic disorders, which invokes the concept of a psychodynamic conflict derived from psychoanalytic theory. Psychosomatic patients appear to be unable to describe feelings in words, show a marked paucity of fantasy, and do not make significant internal psychological changes in these areas in the course of psychodynamically oriented psychotherapy. It is suggested that neurophysiological hypotheses may be more useful for understanding psychosomatic processes and specifically that disturbances in the function of the palleostriatral dopamine tract are related to psychosomatic disorders. Testable inferences from this hypothesis are proposed, including the suggestion that clinically and neurophysiologically, schizophrenia and psychosomatic disorders are the obverse of one another.
 ...
PMID:Denial revisited: reflections on psychosomatic theory. 121 51

Cranial computed tomography (CT) examinations performed on patients with schizophrenia, affective disorders or on patients with anorexia and bulimia nervosa revealed morphological brain alterations. In patients with eating disorders these structural changes were characterized by enlarged ventricles and sulci. Malnourishment-induced hormonal and metabolic disturbances may be responsible for this morphological brain alteration which, due to its reversibility after clinical remission, is frequently called 'pseudoatrophy'. As patients with alcohol dependency also display a cerebral pseudoatrophy, the search for similarities between alcoholics and patients with eating disorders may help to elucidate some of the pathogenetic factors which cause the CT findings in patients with different psychiatric or psychosomatic disorders.
 ...
PMID:Hormonal and metabolic mechanisms in the development of cerebral pseudoatrophy in eating disorders. 350 12

Family morbidity in chronic pain patients could indicate genetic vulnerability to depressive spectrum disorders or presence of pain behaviour models. Assessment of family morbidity is an area of chronic pain research which has been neglected. In the present study, the frequency and nature of the family psychiatric morbidity of 203 consecutive chronic pain patients has been assessed and compared with that of 140 non-pain psychiatric patients. 30% of chronic pain patients and 33.6% of non-pain psychiatric patients had family psychiatric morbidity. The commonest illness in families of pain patients were found to be alcoholism, psychosomatic disorders and chronic pain. Schizophrenia and affective disorders were reported significantly more often in families of non-pain patients. 53% of psychogenic pain disorder patients had a positive family morbidity. Alcoholism among male relatives, and chronic pain and hypertension more often among female relatives, was another significant observation. No significant difference was found between chronic pain patients with and without family morbidity with regard to socio-demographic variables and clinical diagnosis.
 ...
PMID:Family morbidity in chronic pain patients. 367 Aug 67

Our investigation of the pattern of mortality among former inpatients in nine diagnostic groups was based on deaths found among 4,869 former inpatients of the University of Iowa Psychiatric Hospital, Iowa City, during a ten-year period. Comparisons were made with expected values based on a relevant Iowa control population. The first two years of follow-up was a period of great risk but not after. Excessive mortality from "unnatural" causes was found among patients of either sex with an affective disorder, schizophrenia, alcohol or other drug abuse, and personality disorders, among men with acute schizophrenia or neuroses, and among women with depressive neuroses. Women with acute schizophrenia or a psychophysiologic disorder or special symptom were at risk for a "natural" death. These findings confirm the risk of reduced life span that patients in all nine categories share.
 ...
PMID:The Iowa record-linkage study. III. Excess mortality among patients with 'functional' disorders. 396 56

We have classified 200 pre-adolescent patients, with whom we have met during the last three years, into the following four types: school refusal and obsessive behavior, psychosomatic disorders, depressive reactions, and schizophrenic disorders. During our therapeutic process, we realized that even though their symptoms seemed varied and severe, they disappeared after comparatively short periods. The pre-adolescent period is a turning point at which the children depart from their earlier relationships with parents and start to form new ones with friends. We facilitated the patients' developmental process in this period so that they would recover naturally by themselves. However, when we looked at the social phenomena which influence the family and children, we noticed that some factors interfered with the pre-adolescents trying to get over the above-mentioned turning point.
 ...
PMID:Psychiatric disorders of pre-adolescence in Japan. 653 89

In order to explore the possibility of a mutually exclusive relationship between schizophrenia and certain psychosomatic disorders, 354 adult schizophrenic patients, both acute and chronic, were studied with regard to lifetime prevalence of peptic ulcer, bronchial asthma, neurodermatitis and rheumatoid arthritis. Significant evidence to support the hypothesis of mutual exclusivity was found only in the case of peptic ulcer in the overall sample. Prevalence was higher in younger, more acute patients than in older, chronic patients, but this finding was difficult to interpret. Parallel enquiry into the prevalence of schizophrenia and the same disorders among close family members of the patients yielded inconclusive results.
 ...
PMID:Schizophrenia and psychosomatic illness. 706 99

The family physician plays a key role in medical care. In view of the fact that approximately every fourth resident suffers from some mental disorder, the ability of the primary care physician to recognise a disorder as such is of utmost importance. Results of German studies indicate that primary care physicians recognise about half the mental disorders identified on the basis of clinical interviews. The extent to which mental disorders are recognised depends in addition to the psychiatric competence of the primary care physician upon the type and degree of severity of the specific disorder. The rate of recognition is particularly low for mental disorders in childhood and adolescence and among adults who suffer from sleep disorders or neurotic/psychosomatic disorders. On the contrary, over 70% of cases of schizophrenia and affective psychoses and over 90% of all dementia cases are discovered by primary care physicians. Training programmes are valuable aids in improving the skill of primary care physicians at recognising mental disorders. Corresponding programmes, tested for efficacy, are needed in Germany.
 ...
PMID:[Detection of psychiatric diseases in general practice: results from Germany]. 896 93

Psychiatry is a borderline science that has relations on one hand with the methods of knowledge of natural sciences, on the other with those of the humanities. To investigate the bases of its studies, the psychiatric science often refers to literary and philosophical masterpieces. Therefore, the author analyses some examples of the classic fiction which presents psychopathologic issues. Particularly, the author examines some principal topics: anxiety, psychosomatic illness, depression, schizophrenia and delirium.
 ...
PMID:[Literature and psychiatry]. 910 6

For the first time it was possible to study psychiatric inpatient treatment over a period of 7 years in a major German city (Hamburg) using data of 77% of all psychiatric inpatient cases collected by health insurance agencies. Among the most prominent results is the fact that 4 out of 8 illnesses with the highest sum of inpatient days of all treatment cases are psychiatric cases. These are schizophrenia, neurotic disorders, affective psychoses and alcohol abuse. Schizophrenia is the diagnosis which adds up to the highest amount of inpatient days in Hamburg hospitals. Of all psychiatric diagnoses, 35% show up in somatic departments, mainly internal medicine. This is especially true for alcohol and drug abuse, neurotic and personality disorders and organic psychoses. The greatest part of these cases were hospitalised for 0 to 3 days only, which points to the importance of crisis intervention provided by somatic departments. By introducing new offers of low threshold detoxification for drug abuse in psychiatry it was possible to increase the percentage of cases treated in psychiatry departments in the years 1993/94 as compared to 1988/89. During the same period the share of cases suffering from all kinds of psychoses decreased in psychiatry whereas the percentage of cases with drug abuse, neurotic and personality disorders rose. In nonpsychiatric departments, diseases seen in the context of alcoholism as well as neuroses and functional disorders prevail among the group of mental disorders. In internal medicine 6% of all cases are related with all kinds of addiction including its respective somatic consequences and 2-3% with neurotic and psychosomatic disorders. Looking at the amount of inpatient days 11.2% are spent for treating alcohol abuse, alcohol psychoses and diseases of liver and pancreas by patients of 15 to 65 years of age. In the light of these results it is suggested to set up psychiatric liaison-services in somatic departments, especially in internal medicine, to deal with psychosomatic and neurotic disorders and of course, alcoholism. This would help to lower hospitalisation costs. The introduction of motivational approach to the treatment of alcoholism in internal medicine departments appears warranted. Such changes of approach would result in new points of emphasis also in psychiatry.
 ...
PMID:[Analysis of psychiatric hospital cases in Hamburg 1988-1994--developmental trends, health care deficiencies and prospects]. 933 82


1 2 Next >>