Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036341 (schizophrenia)
60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of this study was to explore relationships among perennial allergic rhinitis and personality traits in a nonpsychiatric female population of proven allergic status. Female subjects were assigned to the allergic (N = 22) or nonallergic group (N = 18) on the basis of skin prick test and self-reported allergic status. Analysis of MMPI profiles showed that allergic subjects scored significantly higher on the Hypochondriasis (Hs) and Social Introversion (Si) scales and significantly lower on the Correction (K) and Ego Strength (Es) scales. The results suggested that women with perennial allergic rhinitis show poorer psychological functioning than nonallergic women. In addition, the number of allergies was positively correlated with T scores on the Hs, Depression (D), Hysteria (Hy), Psychasthenia (Pt), Schizophrenia (Sc), Si, and Conscious Anxiety (A) scales, and negatively correlated with T scores on the K and Es scales. Skin reactivity to house dust mite and grass pollen allergens were positively correlated with scores on Si, whereas skin reactivity to grass pollen and mold allergens was positively correlated with D and Pt (grass) and Pd and Sc (grass and mold). Two possible mechanisms explaining the link between psychological factors and allergic rhinitis include (1) the effect of cortisol on IgE production or (2) the production of mediators during an allergic reaction which travel from the nose to the brain.
...
PMID:A Minnesota Multiphasic Personality Inventory profile of women with allergic rhinitis. 831 Jan 14

Acute intermittent porphyria mimics a variety of commonly occurring disorders and thus poses a diagnostic quagmire. Psychiatric manifestations include hysteria, anxiety, depression, phobias, psychosis, organic disorders, agitation, delirium, and altered consciousness ranging from somnolence to coma. Some patients develop psychosis similar to schizophrenia. Psychiatric hospitals have a disproportionate number of patients with this disorder as only difficult and resistant patients accumulate there. Presence of photosensitive porphyrins in the urine is diagnostic. When porphyrins are absent, excess of alpha aminolevulinic acid and porphobilinogen are present in the urine. The definitive test is to measure monopyrrole porphobilinogen deaminase in RBCs. This diagnosis should be entertained in the following situations: (a) unexplained leukocytosis; (b) unexplained neuropathy; (c) etiologically obscure neurosis or psychosis; (d) 'idiopathic' seizure disorder; (e) unexplained abdominal pain; (f) conversion hysteria, and (g) susceptibility to stress. Porphyria is important in psychiatry as it may present with only psychiatric symptoms; it may masquerade as a psychosis and the patient may be treated as a schizophrenic person for years; the only manifestation may be histrionic personality disorder which may not receive much attention. Diagnosis is based on a high index of suspicion and appropriate investigation. Various psychotropic drugs exacerbate acute attacks. While it is important not to use the unsafe drugs in porphyric patients, it is also imperative to look for this diagnosis in cases where these drugs produce unprecedented drug reactions.
...
PMID:Porphyria: reexamination of psychiatric implications. 865 42

This is a retrospective study that aimed at studying the diagnostic stability of psychiatric diagnoses over a 4-year period. Three-hundred and twelve patients (n = 312) admitted more than once to Al Ain in-patient unit from January 1, 1990 to December 31, 1993, were the subjects for this study. The sample included patients with the following index diagnoses: acute psychoses (n = 37), alcohol abuse (n = 15), bipolar disorder (n = 27), depressive disorders (n = 63), drug abuse (n = 21), hysteria (n = 23), neurotic disorders (n = 50) and schizophrenia (n = 76). Diagnoses on discharge for first admissions were considered the index diagnoses. The shift from index diagnoses to subsequent diagnoses was counted. Diagnostic stability was calculated as the percentages of index diagnoses that did not change over time. In nearly half of the patients the index diagnoses changed over the 4-year period. Highest diagnostic stability was found in patients with index diagnoses of alcohol abuse, schizophrenia and drug abuse (92%, 74% and 71% respectively), while the lowest stability was found in patients with neurotic, hysterical, depressive disorders, acute psychoses and bipolar disorders (38%, 48% and 45%, 42%, 52% respectively). Two distinct patterns of shifts were noted. First shift occurred between functional psychoses and second shift between depressive and neurotic disorders. This study provides further support to the notion that diagnostic stability in clinical practice is still far from being satisfactory.
...
PMID:Stability of psychiatric diagnoses in clinical practice. 888 44

Minnesota Multiphasic Personality Inventory profiles were analysed in 55 patients with pseudoseizures (40 patients with pseudoseizures only-pure group, and 15 patients with both pseudoseizures and epilepsy-mixed group). For each of the 10 clinical scales, there were no significant differences between the groups in mean T-score values or the incidence of pathological scores (T-score of 70 or above). In 87.3% of cases in the entire sample (groups combined), at least one clinical scale was elevated in the pathological range. For the combined groups, scales having the highest mean values as well as highest incidence of pathological scores were Schizophrenia, Hysteria and Depression. The mean profile of the entire sample (n = 55) had a two-point code of 8-3 with Schizophrenia and Hysteria as profile peaks. Application of three sets of published criteria for hysteria or conversion yielded markedly different results. This finding underscores the difficulty in evaluating the role of hysteria in pseudoseizures in the absence of a single standard. Mean values and the overall profile of this patient sample were remarkably similar to those found in two previous studies.
...
PMID:Personality profiles of patients with pseudoseizures. 906 16

The aim of this study was to investigate the concepts of reactive and hysterical psychoses and how they are classified in standardized diagnostic systems. To this end we identified all of the patients who had been admitted to a psychiatric in-patient unit and diagnosed as suffering from psychogenic psychosis, reactive psychosis, hysterical psychosis or hysteria, using ICD-9 criteria. The case notes of these patients were then re-examined and diagnoses reached using DSM-III-R, DSM-IV and ICD-10 criteria and the Present State Examination (PSE)/CATEGO computer program. The objective of this study was to evaluate the agreement between the diagnoses of reactive and hysterical psychosis obtained using ICD-9 criteria with those obtained using the DSM-III-R, DSM-IV, ICD-10 and PSE diagnostic systems. A total of 67 case notes were identified in which the above diagnoses had been made: 27 cases with ICD-9 'hysteria' and 26 cases with 'other reactive and not otherwise specified psychoses'. Using the DSM-III-R criteria, 27 cases were diagnosed as psychotic disorder NOS, 12 as brief reactive psychosis and 11 as bipolar disorder. Using the DSM-IV criteria, 21 cases were diagnosed as psychotic disorder NOS, 11 as mood disorder, 7 as brief disorder without stressor, and 12 as brief disorder with stressor. Using the ICD-10 criteria, 18 cases were diagnosed as unspecified non-organic psychosis, 12 as mood disorder, 10 as acute and transient psychotic disorder without stressor and 13 as acute and transient psychotic disorder with stressor. Using the PSE/CATEGO program, the most common diagnoses were class 'S' schizophrenia (17), class 'P?' uncertain psychosis (16) and class 'M+' mixed and manic affective disorder (11). Using the kappa coefficient a very low level of agreement was found between ICD-9 'hysteria' and 'other reactive and non-specified psychoses' and the corresponding categories of DSM-III-R and the PSE/CATEGO program. We concluded that, although DSM-III-R provides operational criteria for brief reactive psychosis, and DSM-IV and ICD-10 provide such criteria for brief or acute psychotic disorder, these bear little relationship to the original concept of the disorder. The PSE/CATEGO program provides a very systematic approach to symptomatology, but the diagnostic classes have little clinical usefulness.
...
PMID:Psychogenic (reactive) and hysterical psychoses: a cross-system reliability study. 906 75

Personality assessed with the Minnesota Multiphasic Personality Inventory (MMPI) in college was used to predict exercise behavior measured at midlife in 3,630 men and 796 women enrolled in the University of North Carolina Alumni Heart Study. Logistic regression models were fitted for each of the MMPI clinical scales to test the predictive effect of personality, gender, and their interaction on adult exercise behavior. Lower depression, social introversion, and psychopathic deviance scores were associated with increased probability of exercising in midlife for both men and women. Furthermore, better psychological health (indexed by lower hypochondriases and psychasthenia) in college was generally predictive of increased exercise for men, whereas higher scores on these same factors predicted midlife exercise for women. There were two other patterns of gender interactions: (a) for men, lower scores on hysteria and schizophrenia scales were associated with increased probability of exercising at midlife, whereas these factors were unrelated to exercise for women and (b) for women, lower ego strength and higher college scores on paranoia and mania were associated with exercise behavior at midlife. These data suggest that early adulthood personality predictors of exercise behavior at midlife are both gender-neutral and gender-specific; that is, where no gender differences exist, healthier personality traits predict exercise at midlife, and when gender differences do occur, healthier college patterns of personality predict exercise behavior for men and sedentary behavior for women.
...
PMID:Personality factors differentially predict exercise behavior in men and women. 910 71

We performed pattern analysis of the Minnesota Multiphasic Personality Inventory (MMPI) profiles of 55 patients with pseudoseizures in order to establish whether there was any single pattern which would be sufficient to characterize the entire sample. Two published methods of pattern analysis were used. Neither method revealed a single pattern or profile code which could best characterize the sample. The Graham method revealed that the Hysteria and Schizophrenia scales were most likely to be found among the profile leads, followed by the Depression, and to a lesser extent, the Hypochondriasis scales. According to the Friedman method, 30.9% of the records could be classified as 'spike', 'two-point code' or 'three-point code'. The most striking finding of the study is that 40% of the profiles had four or more clinical scale elevations. Furthermore, 91% of those profiles with multiple elevations had elevations on both the neurotic and psychotic scales. This suggests that a substantial proportion of MMPI profiles in this sample are complex, and the clinical picture which they reflect requires a broader scope of psychological analysis beyond that of a single psychological mechanism.
...
PMID:Analysis of MMPI patterns in patients with psychogenic pseudoseizures. 953 Sep 36

The present study investigated the relationship between offender type and personality in 21 juvenile males adjudicated for crimes of a sexual nature and 30 juvenile males adjudicated for nonsexual offenses including Possession of Narcotics, Burglary, Criminal Mischief, Assault, and other crimes involving property. Subjects who were aged 13 to 17 years (mean age 15) and committed to the State of Connecticut, Long Lane School, were administered the Minnesota Multiphasic Personality Inventory-Adolescent (MMPI-A). Scores on Psychopathic Deviate and Schizophrenia scales contributed most to the juveniles being classified as sex offenders, whereas scores on Hysteria and Psychasthenia contributed primarily to subjects being classified as nonsex offenders. A single discriminant function attained statistical significance, thereby correctly classifying 77% of the nonsex offenders and 71% of the sex offenders. Results indicate that sex offenders may be distinguished from nonsex offenders according to clinical scales of the MMPI-A.
...
PMID:Use of the MMPI-A to assess personality of juvenile male delinquents who are sex offenders and nonsex offenders. 977 69

The present study examined the relation between two Synder Hope subscales (Agency: goal motivation; Pathways: goal planning) and adjustment problems (a composite of seven MMPI-2 clinical scales). Each of 354 university students completed both the Hope Scale and the MMPI-2. Whereas scores on Hope, Agency, and Pathways subscales were each negatively related to the maladjustment composite score, the relation was significantly stronger for the Agency than for the Pathways subscale. For individual clinical scales, the Agency subscale offered better prediction than the Pathways subscale for all selected clinical scales except Hysteria and Psychopathic Deviate. The Agency subscale also offered better prediction than the Hope Scale for Psychaesthenia and Schizophrenia. Applications for health professionals and directions for research are discussed.
...
PMID:Differential prediction of maladjustment scores with the Snyder Hope subscales. 992 83

The aim of this study is to explore the effects of ChunDoSunBup Qi-training on personality traits. Twenty-six normal healthy subjects (mean age = 26.58 +/- 6.56) and 26 CDSB Qi-trainees (mean age = 27.74 +/- 5.21) participated in this study. Analysis of MMPI profiles showed that CDSB Qi-trainees scored significantly lower on Depression (D), Hysteria (Hy), Paranoia (Pa), Schizophrenia (Sc) and Frequency (F) and significantly higher on the Correction (K) Scales. In addition, CDSB Qi-trainees reported a significantly lower Cook-Medley Hostility (Ho) scale than that of controls. This preliminary study suggests that CDSB Qi-training may be effective in protection as well as restoration of emotional, psychological symptomatology and personality trait disorder.
...
PMID:A Minnesota multiphasic personality inventory profile of ChunDoSunBup qi-trainees: a preliminary study. 1059 39


<< Previous 1 2 3 4 5 6 7 8 Next >>