Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036341 (schizophrenia)
 60,220 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Correlational and contingency analytical techniques were used to investigate the relationship between subtest scores on the Minnesota Multiphasic Personality Inventory (MMPI) and coronary heart disease (CHD) risk factors in 1000 submariners. Groups of personality traits, both enhancing and protecting against risk of heart disease, were identified in these subjects. Personality trait patterns tending to be least associated with cardiovascular risk are tentatively identified by the three MMPI scales: psychasthenia, schizophrenia, and social introversion. On the other hand, the scales most strongly related to CHD risk in the submariner sample were denial of symptoms as measured by the K-scale, hypochondriasis, and hysteria. While the inherent inaccuracy in the prediction of CHD risk in young healty individuals limits generalization from these findings, the potential utility of the MMPI to assist in risk detection is indicated. Comparisons of cigarette smoking, coffee drinking, and alcohol consumption with personality characteristics identified by the MMPI yielded trait clusters associated with each addictive habit. Cigarette smoking and alcohol consumption tended to correlate with traits positively associated with CHD risk. The correlations between those addictive habits and MMPI subtest scores were most significant for the F-scale, which measures inordinate tendencies to exaggerated emotional symptoms, and for the psychopathic deviate and hypomania scales. Significant negative correlations were found between the amount of coffee consumed and those personality traits negatively associated wit CHD risk. These negative relationships were most significant for the MMPI scales schizophrenia and psychasthenia. Though the relationships were not necessarily construed to be causal, the contrasting modes through which these drug-associated habits appeared to relate to cardiovascular risk lend some support to the assumption that individuals with various specific sets of personality characteristics tend to incorporate these additive behaviors into their behavior repertoire in very different ways.
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PMID:Relationship of personality factors and some social habits to cardiovascular risk in submariners. 708 56

People presenting with hypochondriacal complaints are commonly regarded as difficult to engage in psychotherapy. The clinical experiences described here indicate that when therapists communicate their empathic understanding of the patient's distress, the patient's suffering is decreased and it is possible to engage him or her in treatment. These results are demonstrated with regard to eight patients. Treatment failures using this method are demonstrated in a case where its application was delayed and in cases of hysteria and schizophrenia, where the method is not applicable. These clinical results can be conceptualized using ideas of self-psychology.
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PMID:The opening phase of psychotherapy of hypochondriacal states. 715 21

We surveyed the clinical records kept at the outpatient psychiatric clinic at the Umtata Hospital, Transkei. The four commonest psychiatric disorders diagnosed at the clinic were schizophrenia, depression, epilepsy, and anxiety states. Other diagnoses included alcoholism, hysteria, confusional states and organic brain syndromes.
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PMID:Psychiatric disorders in a developing community as reflected by archival material. 724 12

Ten patients with the stable syndrome of hysteria were matched for age, sex, handedness, and full-scale WAIS IQ with ten controls, ten psychotic depressives and ten schizophrenics. All were subjected to an extensive neuropsychological test battery. Compared to the controls, the hysteria group exhibited bifrontal impairment (R = L) and, globally, greater dysfunction of the nondominant hemisphere. A G analysis provided a complete separation between the hysteria and controls. However, a D-index analysis showed that the hysteria group was more impaired than normals and depressives because of greater dysfunction of the dominant hemisphere, whilst schizophrenia showed greater nondominant hemisphere dysfunction than hysteria. Further, a cluster analysis on the 40 subjects produced three clusters: normal controls, depressives, and a schizophrenia-hysteria grouping. These findings are interpreted as suggesting that dominant hemisphere dysfunction is fundamentally related to the syndrome of hysteria and that the dysfunction of the nondominant hemisphere is brought about by associated features: the female excess, the emotional instability and dysphoric mood, the presence of asymmetrical pain, and conversion symptomatology. It is further argued, in view of the familial associations, that hysteria in the female is a syndrome equivalent to psychopathy in the male (who also exhibits dominant hemisphere dysfunction) and might represent in the female a (relatively benign) variant of schizophrenia characterized by imprecise verbal communications, a subtle form of affective incongruity, together with the conversion parameter.
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PMID:A neuropsychological study of the stable syndrome of hysteria. 727 78

This is the third report of a patient with dissociated personality followed for 38 years. There has been a gradual integration of the dissociated states. The most remarkable aspect of the clinical course has been the patient's excellent work record in contrast to a severe restriction in her social life. The original diagnosis of hysteria was changed to schizophrenia. Evidence is presented to show that the diagnosis of schizophrenia was incorrect. The authors believe that dissociated states occur more frequently than diagnosed, and that the syndrome should be given independent diagnostic status.
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PMID:Dissociated state. Status of a case after 38 years. 742 67

Patients who have the wish to be admitted and treated repeatedly in hospitals are a fascinating although still poorly understood group. Those who have no apparent organic basis for their complaints are especially interesting and challenging, since they often demand and sometimes receive potentially dangerous somatic treatments such as operations and medications. Such patients receive a wide range of psychiatric diagnoses, such as hysteria, Briquet's syndrome, factitious illness, Munchausen's syndrome, malingering, and schizophrenia. We recently treated a young woman who had been given most of these diagnoses, whose case history presented us with an opportunity to review problems in differential psychiatric diagnosis as applied to this frequently confused and confusing problem area.
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PMID:DSM-III differential diagnosis of Munchausen's syndrome. 742 72

The investigation of personality traits of migraineurs with the Minnesota Multiphasic Personality Inventory (MMPI) is an important line of research, but so far has led to diverse conclusions. In this study, the MMPI (Chinese edition) responses of 50 Chinese subjects (10 men, 40 women) with migraine (4 migraine with aura, 46 without aura), during frequent headache attacks were compared with 30 nonheadache healthy control subjects (6 men, 24 women). Statistical analysis was made between the two groups. The results revealed that subjects in the migraine group had significantly higher scores on subtests of neurotic, (hypochondriasis, depression, hysteria, and psychasthenia), schizophrenia, and social introversion (P < 0.05 to 0.001). Utilizing the American T-score, we found the migraine group's MMPI profile was a typical 1.2.3.7 model. These results suggest migraineurs with frequent headache attacks have multiphasic personality abnormalities and partial cerebral function disturbances.
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PMID:An MMPI control study: Chinese migraineurs during frequent headache attack intervals. 759 42

A psychometric analysis on patients with duodenal ulcer using latent structure coefficients (Loevinger and Mokken) showed that the MMPI subscales of depression, psychasthenia, hypochondriasis, hysteria, schizophrenia and social introversion all could be considered as indicators of Eysenck's dimension of neuroticism. Both a MMPI neuroticism scale of 15 items (MMPI/N-15) and of 21 items (MMPI/N-21) were psychometrically valid, i.e. the total score was a sufficient statistic. Patients with duodenal ulcer who improved during treatment also had a significant decrease in their neuroticism scores, whereas patients who did not improve had unchanged neuroticism scores. In other words, neuroticism is secondary to the clinical symptoms of duodenal ulcer (a psychological adjustment to illness) and not an etiological factor.
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PMID:The validity of Eysenck's neuroticism dimension within the Minnesota Multiphasic Personality Inventory in patients with duodenal ulcer. The Hvidovre Ulcer Project Group. 784 60

The correlations of symptoms of hysteria with 87 symptoms relevant for diagnosing schizophrenia were examined in a sample of 112 patients (70 women and 42 men whose mean age was 38.1 yr., SD = 9.8) with DSM-III diagnosis of schizophrenia. Hysterical symptoms were recorded in 37.5% of the schizophrenics. No significant relationships (phi coefficients) were found to key symptoms of schizophrenia.
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PMID:Correlates of hysterical symptoms in schizophrenic patients. 798 33

Among a sample of 40 severe migraine sufferers, males and females displayed common personality profiles. Both sexes exhibit heightened scores on those MMPI clinical scales associated with neuroticism (hypochondriasis, depression and hysteria). Female migraine sufferers were further characterised by elevated scores on the primary scales constituting the psychotic tetrad (paranoia, psychaesthenia, schizophrenia, and hypomania). Migraine females appeared to differ from male patients with respect to a dimension associated with sex-role conformity (loaded on the L-scale and masculinity-femininity). The implication of these results are considered.
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PMID:MMPI profiles of male and female migraine sufferers. 821 5


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