Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0035412 (
rhabdomyosarcoma
)
6,156
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Clones were isolated from two flow-sorted chromosome 13 libraries. Twenty-five clones were localized to various regions of chromosome 13, using a well-characterized panel of rodent x human hybrid cell lines. Eight DNA markers were localized to 13q14.2----q22, where the gene for
Wilson disease
, a recessive disorder of copper metabolism, was previously assigned. The new markers will be useful for the diagnosis of presymptomatic sibs of
Wilson disease
patients. We isolated six DNA clones proximal to the retinoblastoma gene, a region in which a translocation associated with
rhabdomyosarcoma
has been observed. Probes for both of these regions will be useful for the cloning of the genes involved in these diseases.
...
PMID:Isolation and regional localization of 25 anonymous DNA probes on a chromosome 13 hybrid panel. 191 27
