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Query: UMLS:C0035412 (rhabdomyosarcoma)
 6,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Facial nerve palsy due to malignant tumours is uncommon in childhood and adolescence. If present the malignancy may be primary or metastatic, and usually brain tumours, leukaemias, or lymphosarcomas are found. Rhabdomyosarcomas, parotid malignancies, Ewing's sarcomas, Wilms' tumours and neuroblastomas are rare. The nerve lesion may be due to direct tumour infiltration, external pressure on the nerve and secondary ischaemia. In disseminated malignancy the lesion is usually due to extending intraneural infiltration and all parts of the nerve may be affected. If facial nerve palsy coexists the prognosis in childhood malignancies is extremely poor.
HNO 1976 Jul
PMID:[Childhood facial paralysis due to tumours (author's transl)]. 18 62

Rhabdomyosarcomas are rare tumours of the paranasal sinuses nad orbit. However they represent a broad group of childhood malignant soft tissue tumours. The presentation of these tumours often causes great diagnostic difficulty, especially if they involve the medical orbital wall. Certain diagnostic problems are discussed from our own experiences.
HNO 1978 Jun
PMID:[An orbital rhabdomyosarcoma mimicking a mucocele (author's transl)]. 66 95

Aural polyps or granulation tissue, though usually due to infection, may represent a neoplasm, the most frequent malignant tumour in childhood being rhabdomyosarcoma. We report a 9-year-old boy from whom an aural polyp was removed 4 years ago, with the histological diagnosis of a botryoid (alveolar type) rhabdomyosarcoma. Surgery and chemotherapy with cyclophosphamide, vincristine, adriamycin and actinomycin D were followed by a local recurrence 2 years later. This was treated by chemotherapy and irradiation with 50 Gy; the child has now been free of disease for 2 years. Rhabdomyosarcoma of the ear has a considerably improved cure rate with newer treatments if the diagnosis is made early by biopsy.
HNO 1992 Apr
PMID:[Differential diagnosis of an ear canal polyp]. 160 83

Two children with nasopharyngeal rhabdomyosarcoma are used to discuss the relevance of the histopathological investigation of adenoid tissue. Histopathological investigation should only be omitted if there is complete agreement between symptoms, intra-operative findings and macroscopic findings. Histopathology is advised for very large adenoids, alteration of consistency and in older children or young adolescents.
HNO 1988 Apr
PMID:[When should removed adenoids be studied histologically?]. 341 Jul 54

The differential diagnosis of pharyngeal tumors includes malignomas as well as chronic inflammatory processes. Squamous cell carcinoma is the most prevalent malignoma of the pharynx, representing about 90% of all malignomas of the head and neck. Malignant lymphomas, lymphoepithelial tumors (Schmincke's tumor) and anaplastic carcinomas are less prevalent. Amelanotic melanoma, rhabdomyosarcoma and extramedullary plasmocytoma are rare malignomas of the pharynx. Infectious diseases may also be a cause of pharyngeal tumors which have been reported to be associated with mycobacterial infections, syphilis, leproma, malleus and anthrax. Sarcoidosis and Wegener's granulomatosis are chronic inflammatory diseases of unknown etiology. We report a case of a 65-year-old female with an 11-year history of a slowly progressing tumor of the nasopharynx who had been admitted to hospital with suspicion of a malignoma.
HNO 1993 Jan
PMID:[Pharyngeal tuberculosis as a differential diagnosis to carcinoma]. 844 87

With the electro-driven import of rhodamine 123, we used single cell fluorescence microscopy to single out the contribution of nitric oxide (NO) in controlling mitochondrial membrane potential expressed by (stationary growing) rhabdomyosarcoma and neuroblastoma cells in culture. The experimental design and the computer-aided image analysis detected and quantitated variations of fluorescence signals specific to mitochondria. We observed that 1) the two cell lines display changes of fluorescence dependent on mitochondrial energization states; 2) mitochondrial fluorescence decreases after exposure of the cells to a NO releaser; 4) the different fluorescence intensity measured under stationary growing conditions, or after activation and inhibition of constitutive NO synthase, is consistent with a steady-state production of NO. Direct comparison of single cell fluorescence with bulk cytofluorimetry proved that the results obtained by the latter method may be misleading because of the intrinsic-to-measure lack of information about distribution of fluorescence within different cell compartments. The kinetic parameters describing the reactions between cytochrome oxidase, NO, and O2 may account for the puzzling (20-fold) increase of the KM for O2 reported for cells and tissues as compared to purified cytochrome c oxidase, allowing an estimate of in vivo NO flux.
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PMID:Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy. 987 43

This article gives an overview of the most common and clinically relevant tumors of the orbit and their treatment. The most common orbital tumors in childhood are cystic tumors, such as dermoid and epidermoid cysts. Capillary hemangiomas are the most common primary benign tumors of the orbit and appear mostly in the first year of life. In contrast teratomas are rare and histologically mostly benign. Neural tumors are, for example, gliomas of the optic nerve and in 25-50% of cases are associated with neurofibromatosis. Rhabdomyosarcoma is a rapidly growing malignant orbital tumor whereby the stage and localization are the most important prognostic factors for survival chance in children. Leukemia can be associated with a chloroma especially in the first decade of life. Lymphoproliferative diseases, vascular and cystic tumors in particular are known as tumors of adulthood. In addition to fibroosseous and mesenchymal tumors, neural forms, such as schwannomas are also important. Secondary tumors of the orbit are often manifested in the nose and paranasal sinuses.
HNO 2010 Jul
PMID:[Tumors and tumor-like lesions of the orbit]. 2060 7