Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0035412 (rhabdomyosarcoma)
 6,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 5-year-old Quarter Horse mare was examined because of a 6-month history of quidding and nasal discharge that contained feed material. Physical examination revealed weight loss and dorsal displacement of the soft palate, caused by a soft tissue mass located at the dorsal aspect of the base of the tongue. Surgical resection of the mass was successfully performed through an oral approach. The histopathologic diagnosis was rhabdomyosarcoma.
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PMID:Rhabdomyosarcoma of the tongue in a horse. 849 87

An immature Baird's tapir (Tapirus bairdii) with a history of seizure-like episodes developed signs of respiratory disease. The initial clinical diagnosis was pneumonia, and antibiotic therapy was started. The animal failed to improve after 14 days of therapy and developed unilateral, bloody nasal discharge. Endoscopic examination and radiography revealed a soft tissue mass in the nasopharynx depressing the soft palate. The tapir died 32 days after initial presentation. Histologic examination of the mass demonstrated a mesenchymal tumor composed of spindle cells with elongate nuclei forming densely packed fascicles. The neoplastic spindle cells showed prominent cross-striations. Immunohistochemistry revealed the cells to be positive for desmin and myoglobin, but negative for smooth muscle actin, confirming diagnosis of rhabdomyosarcoma. Embryonal rhabdomyosarcoma is the most common nasopharyngeal soft tissue tumor of humans, and it has been reported infrequently in dogs, horses, and pigs. Neoplasia should be a differential diagnosis in cases of unilateral nasal discharge and inspiratory stridor, even in young animals.
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PMID:Embryonal rhabdomyosarcoma in an immature Baird's tapir (Tapirus bairdii). 1746 86

The clinical data of two adolescents with unilateral nasal cavity neoplasm were analyzed. Both were male, one was 14-year-old and the other was 17. Both were complained of unilateral nasal obstruction and nasal discharge; The course of disease of the former was one month ,and that of the latter was three month; both were found neoformation in unilateral nasal cavity in medical examination. Occupying lesion in unilateral nasal cavity and sinus were demonstrated in CT scan of two cases. Endoscopy surgery were operated in both cases, incisal opening in labiogingival groove was added in the latter. Pathology of the former was capillary hemangioma and the latter was rhabdomyosarcoma. No findings indicating recurrence has been observed in two cases under 6 months follow-up. Recognition at nasal cavity and paranasal sinus neoplasm in adolescent is essential so that proper management can be initiated.
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PMID:[Unilateral nasal cavity and paranasal sinus neoplasm in adolescent]. 2398 20