Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0035412 (rhabdomyosarcoma)
 6,156 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A rapidly enlarging periocular mass in a child obligates the treating physician to rule out a malignancy, especially a rhabdomyosarcoma. A 3-year-old girl presented with a 5-day history of a rapidly growing episcleral mass superonasal to the globe, adjacent to the superior rectus muscle insertion. The lesion was locally excised. A sarcoma could not be excluded on frozen sections. Permanent sections and electron microscopy revealed nodular fasciitis, a benign lesion with a pseudosarcomatous histologic appearance. No recurrence has been noted at 9 months follow-up. Nodular fasciitis is a benign proliferation which should be considered in the differential diagnosis of a rapidly enlarging subconjunctival or orbital mass in a child.
 ...
PMID:Nodular fasciitis presenting as a rapidly enlarging episcleral mass in a 3-year-old. 236 27

Nodular fasciitis is a common lesion in the head and neck area in the pediatric population. In adults the extremities are the favored location. A 10-year-old girl developed a rapidly growing orbital mass that resulted in medial deviation of the eyeglobe. Clinical diagnosis was a malignant neoplasm, probably rhabdomyosarcoma. A fine needle aspiration biopsy yielded a preoperative diagnosis of nodular fasciitis. The patient underwent surgical resection and had histologic confirmation of the cytologic diagnosis.
 ...
PMID:Nodular fasciitis of the orbit diagnosed by fine needle aspiration cytology. A case report. 824 20