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Target Concepts:
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Query: UMLS:C0035412 (
rhabdomyosarcoma
)
6,156
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hypertrophic osteoarthropathy
is a well-documented paraneoplastic phenomenon in adults. It is a rare, but important finding in children with malignant disease as it can indicate prognosis. We present a case of
hypertrophic osteoarthropathy
associated with primary liver
rhabdomyosarcoma
in a 14-year-old boy.
...
PMID:Hypertrophic osteoarthropathy in primary liver rhabdomyosarcoma. 1460 Jul 94
Hypertrophic osteoarthropathy
(
HOA
) is characterized by digital clubbing, long bone periosteal reaction, and polyarthralgias. Primary familial
HOA
is very rare and is not associated with underlying disorders and has a good prognosis. Secondary pediatric nonneoplastic
HOA
is associated with cystic fibrosis, congenital heart disease, biliary atresia, and inflammatory bowel disease. Secondary neoplastic
HOA
may be associated with intra or extrathoracic tumors.A 5-year-old girl was admitted to our hospital for an abdominal mass, digital clubbing, and diffuse articular pain. The bone scan revealed symmetrical tracer uptake in the long bones. Upper and lower extremity x-rays were diagnostic for
HOA
. Paraneoplastic
HOA
in childhood accounts for not more than 12% of
HOA
paitents.
HOA
has been reported in 2 other cases of
rhabdomyosarcoma
.
...
PMID:Rhabdomyosarcoma associated hypertrophic osteoarthropathy in a child: detection by bone scintigraphy. 1935 78
