Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0035078 (renal failure)
31,970 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chronic renal failure 2096
Sep 1919
insulin 858
renin 785
albumin 751
She 581
parathyroid hormone 472
erythropoietin 445
hemoglobin 409
collagen 403
Mol 350
IgA 295
angiotensin II 277
GFR 265
ACE 239
serum albumin 232
cytokine 230
X-linked 195
Pol 194
proximal tubule 192
PTH 191
alkaline phosphatase 181
HLA 152
vasopressin 149
Alport syndrome 143
MRI 137
C-reactive protein 135
myeloperoxidase 131
fibrinogen 128
gut 125
growth hormone 125
creatine kinase 123
myoglobin 120
tumor necrosis factor 114
HDL 113
Mal 112
calcium channel 108
angiotensin receptor 107
Erythropoietin 106
prothrombin 100
Ang II 99
interferon 99
fibronectin 98
nitric oxide synthase 96
lactate dehydrogenase 96
ATP 93
IL-6 92
angiotensin II receptor 92
transferrin 91
PKD1 90
superoxide dismutase 88
TNF 87
Pseudomonas 87
ATPase 86
thrombin 86
catalase 85
glycoprotein 84
CRF 81
natriuretic peptide 79
ferritin 79
GBM 78
reserved 78
erythroid 76
cystatin C 75
renal amyloidosis 74
collecting duct 73
serum protein 73
amylase 71
endothelin-1 70
atrial natriuretic peptide 69
lipopolysaccharide 68
calcineurin 68
interleukin-6 67
mTOR 65
CD4 65
lymphoid 65
endoplasmic reticulum 62
ARF 61
beta 2-microglobulin 61
COL4A5 61
more...
Disease
renal failure 31970
renal disease 4136
hypertension 3670
diabetes 2850
chronic renal failure 2791
proteinuria 2347
acute renal failure 2055
glomerulonephritis 1391
cancer 1312
anemia 1293
renal insufficiency 1201
heart failure 1186
sepsis 1034
nephrotic syndrome 1006
sepsis 944
stroke 929
diabetic nephropathy 892
glomerulosclerosis 860
uremia 814
cardiovascular disease 741
thrombocytopenia 706
tumor 699
renal impairment 680
multiple myeloma 645
myocardial infarction 636
cirrhosis 630
ischemia 613
atherosclerosis 580
hyperparathyroidism 570
systemic lupus erythematosus 563
hypercalcemia 514
congestive heart failure 513
vasculitis 470
pneumonia 463
nephritis 463
amyloidosis 444
type 2 diabetes 435
polycystic kidney 431
liver disease 429
obesity 412
interstitial nephritis 411
hemolytic anemia 364
respiratory failure 351
hemolytic uremic syndrome 337
encephalopathy 334
IgA nephropathy 321
disseminated intravascular coagulation 320
acute tubular necrosis 307
HIV 301
coronary artery disease 294
depression 288
malnutrition 287
microalbuminuria 283
peritonitis 278
hyperglycemia 273
lupus 273
bone disease 273
lupus nephritis 270
coma 268
membranous nephropathy 254
heart disease 250
azotemia 250
urinary tract infection 250
dysplasia 249
dehydration 249
pulmonary edema 248
infectious diseases 245
coagulopathy 243
vascular disease 243
essential hypertension 237
blindness 230
carcinoma 230
hydronephrosis 230
hepatorenal syndrome 229
pyelonephritis 227
hypoglycemia 227
glomerulopathy 226
renal artery stenosis 225
Alport syndrome 224
anuria 220
more...
Symptom
pain 517
diarrhea 422
seizures 347
vomiting 328
abdominal pain 307
oliguria 302
anesthesia 268
weakness 255
nausea 209
dyspnea 207
respiratory distress 200
headache 199
fatigue 187
anorexia 161
polyuria 148
collapse 112
myalgia 106
cough 104
angina 100
hypothermia 95
chest pain 95
hemoptysis 84
hepatomegaly 77
nausea and vomiting 77
lethargy 73
Ill 73
bone pain 71
arthralgia 64
cachexia 63
analgesia 60
back pain 60
polydipsia 56
overweight 54
splenomegaly 53
dizziness 50
shortness of breath 49
constipation 49
hepatosplenomegaly 48
livedo 46
sleepiness 45
flank pain 45
erythema 44
ataxia 44
chills 42
functional recovery 40
hypoproteinemia 40
agitation 39
dysuria 35
myoclonus 35
fever of unknown origin 34
hypotonia 32
thinning 30
discomfort 30
tremor 28
discomfort 28
insomnia 27
paresthesia 26
asthenia 26
paresis 26
low back pain 25
syncope 25
paraparesis 24
pallor 24
tense 23
numbness 23
renal colic 23
regurgitation 22
cyanosis 21
acute abdomen 21
epigastric pain 21
tachypnea 20
muscle cramps 20
exhaustion 19
tonic-clonic seizure 19
flushing 19
cerebellar ataxia 19
enuresis 18
starvation 17
sore throat 14
blurred vision 14
more...
Drug
Dial 615
Nephron 531
Nephron 525
Cardiovasc 444
PTH 195
Dermatol 130
lysine 77
Monit 58
Captopril 47
Albumin 44
CTX 42
CSF 41
Angiotensin II 41
ascorbate 38
ampicillin 37
vitamin E 36
Rituximab 28
MAP 26
Serum albumin 23
Indomethacin 23
Bortezomib 23
ROS 22
ETA 22
nitroglycerin 21
caffeine 21
Adriamycin 20
Prednisone 19
Eculizumab 19
Propofol 19
Aprotinin 17
ROC 17
Tacrolimus 17
IFN-gamma 16
IL-2 16
Spectrum 16
Acyclovir 16
Epoetin alfa 15
Epoetin 14
ENT 14
DMSA 14
PMPA 14
DDAVP 13
Ramipril 13
G-CSF 13
Rasburicase 13
Dakar 13
Gel 13
DDAVP 12
Omniscan 12
Terlipressin 12
Growth hormone 12
Rasburicase 12
Iohexol 12
Lanthanum carbonate 12
Tenofovir 12
Prednisolone 12
Terlipressin 12
Growth hormone 12
CTX 11
Methylprednisolone 11
Glycerol 11
NAG 11
EPI 11
CTX 10
Phenytoin 10
Theophylline 10
Darbepoetin alfa 10
AmBisome 10
Paraffin 9
MOF 9
Argatroban 9
Lovastatin 9
Tolvaptan 9
Doxycycline 9
Aliskiren 9
NADH 9
Portal 8
Perindopril 8
CPR 8
Cimetidine 8
more...
Enzyme
renin 785
ACE 433
alkaline phosphatase 181
creatine kinase 178
peroxidase 168
lactate dehydrogenase 114
superoxide dismutase 101
ATPase 92
catalase 92
alanine aminotransferase 91
mitogen-activated protein kinase 91
aspartate aminotransferase 87
thrombin 85
thromboplastin 78
ERK 69
calcineurin 69
alpha-galactosidase 67
NO synthase 53
glutathione peroxidase 48
AST 41
protein kinase C 41
protein kinase 40
lipase 40
proteasome 37
caspase-3 34
NADPH oxidase 33
APC 33
CD10 31
trypsin 31
xanthine oxidase 29
kallikrein 28
reverse transcriptase 28
focal adhesion kinase 28
phosphodiesterase 28
PAH 28
NADPH oxidase 26
uricase 25
gamma-glutamyl transpeptidase 24
alcohol dehydrogenase 21
AGT 21
plasmin 20
urokinase-type plasminogen activator 20
tissue plasminogen activator 20
lysozyme 20
aldose reductase 20
luciferase 20
MAP 19
MEK 17
P-glycoprotein 17
neuraminidase 16
adenine phosphoribosyltransferase 16
lipoprotein lipase 16
beta-lactamase 15
glucose-6-phosphate dehydrogenase 15
lecithin:cholesterol acyltransferase 15
RNase 15
phospholipase A2 15
PRA 15
RNase 15
hypoxanthine-guanine phosphoribosyltransferase 15
collagenase 14
cholesterol acyltransferase 14
methylenetetrahydrofolate reductase 13
glutathione S-transferase 13
CAD 13
CAD 13
methylenetetrahydrofolate reductase 13
CAD 13
BMT 13
AMP-activated protein kinase 13
RNA polymerase 13
phosphatidylinositol 3-kinase 12
acetylcholinesterase 12
glutathione reductase 12
urease 12
adenylate cyclase 11
elastase 11
beta-glucuronidase 11
urease 11
ceruloplasmin 11
more...
Compound
creatinine 3857
Clin 3640
Dec 2047
calcium 1521
sodium 1216
urea 1195
water 816
glucose 782
phosphate 654
nitrogen 631
Dial 614
potassium 562
oxygen 537
DNA 524
Cardiol 411
acetate 364
aldosterone 360
phosphorus 352
vitamin D 339
salt 323
His 320
iron 288
oxalate 267
nitric oxide 263
arginine 193
aluminum 166
sulfate 137
carbonate 122
homocysteine 119
ANCA 115
Angiotensin II 108
ethanol 102
PEG 102
ATP 94
iodine 92
CO2 92
TNF 87
glycerol 87
nitrate 86
EDTA 83
EDTA 83
Insulin 82
lysine 81
tyrosine 79
methionine 77
zinc 76
PEG 76
cysteine 75
Cyclosporine 74
galactose 74
hydrogen 74
ammonia 68
prostacyclin 62
alanine 61
cAMP 61
DDP 58
GSH 57
GSH 57
leucine 55
noradrenaline 54
serine 54
Sodium 53
cadmium 53
N-acetylcysteine 51
Optimal 50
Cholesterol 50
hydroxide 49
tryptophan 48
ADP 47
DIC 46
copper 46
25-dihydroxycholecalciferol 46
Ang II 45
Phe 45
ASA 44
Vitamin D 43
tryptophan 42
tryptophan 42
tryptophan 42
CTX 42
more...