Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0035078 (renal failure)
 31,970 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The use of digoxin in some patients with heart failure is controversial. Although many patients taking digoxin have no clinical deterioration after discontinuance of the drug, there is a group who demonstrate clinical deterioration on digoxin withdrawal (patients with enlarged hearts, S3 gallop and supraventricular dysrhythmias). The risk of digitalis administration is high in some patients with increased sensitivity to the drug--renal failure, thyroid disfunction, ischemic heart disease, chronic obstruction lung disease and geriatric patients. It seems reasonable that on 1989 the use of digitalis on heart failure should be preferred on patients with supraventricular arrhythmias, enlarged hearts and S3 gallop.
 ...
PMID:[Role of digitalis in the pharmacologic treatment of cardiac insufficiency]. 263 52

Acute renal failure secondary to bilateral ureteral obstruction in pregnancy is rare. We describe a case of acute renal failure secondary to bilateral ureteral obstruction. A 27 year-old woman at 35 weeks' gestation was referred to our hospital with a diagnosis of acute renal failure. The patient had been well until four days earlier, when she developed an abrupt anuria. She had been administrated excessive amounts of fluids, and unresponsive to parenteral furosemide. She had mild pitting oedema and an S3 gallop with crackles in the lungs. The uterus was enlarged to the expected size with a cervical dilatation of 2 cm in diameter. Her serum creatinine level was 7.0 mg/dl. Renal ultrasound showed bilateral hydronephrosis of severe degree. The patient was immediately hemodialyzed for advanced renal failure with hypervolemia, and a healthy infant was born at the third hour of the HD session without any complication. On the next day, her urine volume was 200 ml/day and serum creatinine level was 6.8 mg/dl. For this reason, the patient underwent cystoscopy and ureteral stents were inserted bilaterally. There was no evidence of ureteral stones or obstructive lesions. After the stenting, the urine volume increased and serum creatinine was decreased gradually to normal level at the seventh day of postpartum. Two weeks later ureteral stents were removed and both infant and patient were completely healthy. To the best of our knowledge, this is the first case of delivery of an infant during a haemodialysis session.
 ...
PMID:Delivery of healthy infant during hemodialysis session. 1072 Feb 19