Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034186 (pyelonephritis)
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Human Gene/Protein
Transmembrane protein 174 10.8
TRB2 9.3
ribonuclease 7 8.8
UTI 8.5
Bone morphogenetic protein 7 8.1
TANGO 7.7
K13 7.6
RNH1 7.3
RNase 7 7.3
ENX 7.3
PFIC 7.3
HCA587 7.2
renal dipeptidase 7.2
GATC 7.1
Tamm-Horsfall glycoprotein 7.0
cytokine synthesis inhibitory factor 6.9
GAX 6.8
ASB 6.8
DRw10 6.7
UPIa 6.6
UPP 6.5
Transcription factor E3 6.5
K23 6.4
chorionic gonadotropin beta subunit 6.4
LSH 6.3
autosomal recessive) 6.2
CPN 6.2
KChIP1 6.1
cysteinyl leukotriene receptor 1 6.1
Nectin-2 6.1
leupaxin 6.1
GPT 6.0
papillary renal cell carcinoma 5.9
SP-A1 5.9
SLC22A12 5.9
AMN 5.9
PIS 5.8
FSAP 5.8
TMP 5.7
SP-A2 5.7
TOB 5.7
alanine-glyoxylate aminotransferase 5.7
O11 5.7
N-acetyl-beta-D-glucosaminidase 5.7
mannose-specific lectin 5.7
SIGIRR 5.7
osteopontin, bone sialoprotein 5.6
zinc metallopeptidase 5.5
chronic renal failure 5.5
AMBP 5.5
HA4 5.4
ELC 5.4
HM3 5.4
N-acetyl-beta-glucosaminidase 5.4
Fez 5.4
IRAK-M 5.4
K15 5.4
NAG 5.3
CXCR1 5.3
renal amyloidosis 5.3
TNF receptor-associated factor 2 5.3
beta 2-microglobulin 5.3
myo-inositol oxygenase 5.2
decay-accelerating factor 5.2
LCN2 5.2
E. coli) 5.2
interferon regulatory factor 7 5.2
FGS 5.2
ACT2 5.1
endocan 5.1
E.coli) 5.1
HLA B 5.1
RPI 5.1
EKLF 5.1
homogentisate 1,2-dioxygenase 5.1
CPZ 5.1
CAII 5.1
C3F 5.1
SAB 5.0
MEST 5.0
phosphate-activated glutaminase 5.0
KLF1 4.9
Cystinosis 4.9
INI 4.9
S100A11 4.8
alpha-1-antichymotrypsin 4.8
H18 4.8
beta-2-microglobulin 4.8
aquaporin-3 4.8
decay accelerating factor 4.7
MCG 4.7
H. influenzae 4.7
SGI 4.6
gamma-sarcoglycan 4.6
PIG-A 4.6
galactose-1-phosphate uridyltransferase 4.6
F11 4.5
glutamic dehydrogenase 4.5
BEN 4.5
ligandin 4.5
EPH 4.5
CPT II 4.5
CXCL5 4.5
E.coli 4.5
Eotaxin 4.5
Interferon beta 4.4
tissue inhibitor of metalloproteinase 1 4.4
GFR 4.4
galectin 3 4.4
Alport syndrome 4.4
IRF-7 4.4
HUS 4.4
EMB 4.4
C3G 4.3
RIFLE 4.3
TFE3 4.3
TZP 4.3
OAS1 4.3
FSGS 4.2
neutrophil gelatinase-associated lipocalin 4.2
collecting duct 4.2
Gal 4.2
PIM1 4.2
JAM 4.1
C-reactive protein 4.1
TIL 4.1
chemokine receptor 2 4.1
EDB 4.1
CIC 4.1
peptide deformylase 4.0
NGAL 4.0
ACHN 4.0
HIP 4.0
PSMA 4.0
transplantation antigen 4.0
calcineurin inhibitor 4.0
MBL2 4.0
IRF7 3.9
NST 3.9
pT3 3.9
ALC 3.9
TLR1 3.9
interleukin-1 receptor antagonist 3.9
RST 3.9
She 3.9
TLR5 3.8
thyroid transcription factor 1 3.8
TH protein 3.8
CRP 3.8
ATTR 3.8
heparin-binding protein 3.8
Lipocalin-2 3.8
BD1 3.8
uromodulin 3.8
FRG 3.8
C3b inactivator 3.7
prune 3.7
HAI 3.7
CGT 3.7
urokinase plasminogen activator receptor 3.7
more...
Disease
pyelonephritis 12.3
Meyer-Betz disease 12.3
Acute urethral syndrome 12.3
nephropathy; hereditary 12.3
Pyloric ulcer 12.3
Bacterial pyelonephritis 12.3
Tuberculous pyelonephritis 12.3
Calculous pyelonephritis 12.3
Bacteriuria in pregnancy 11.9
Acute pyelonephritis 11.8
Emphysematous pyelitis 11.8
Candida pyelonephritis 11.7
Xanthogranulomatous pyelonephritis 11.5
Emphysematous pyelonephritis 11.5
Congenital vesico-ureteric reflux 11.3
Vaginal reflux 11.3
Pyelectasia 11.3
cystourethritis 11.2
Chronic pyelonephritis 11.1
pyohydronephrosis 11.1
pyelonephrosis 11.0
pyelitis 10.8
Citrobacter freundii infection 10.8
acute cystitis 10.8
periurethritis 10.8
Renal scarring 10.7
Asymptomatic bacteriuria 10.4
kidney infection 10.3
Airport malaria 10.3
Calyceal diverticulum 10.3
Renal cyst infection 10.3
cystitis in pregnancy 10.3
calicectasis 10.3
pyometrium 10.3
Ask-Upmark kidney 10.3
pyonephritis 10.3
Hardikar syndrome 10.3
Calyceal diverticulum 10.3
pyonephrosis 10.1
Proteus mirabilis infection 10.0
lower urinary tract infection 9.8
Perinephric abscess 9.8
bacteriuria 9.8
Escherichia infections 9.8
hydrocalycosis 9.8
Renal sarcoidosis 9.8
ureteritis 9.7
Urinary stasis 9.6
Vesicoureteral reflux 9.6
periureteritis 9.5
staghorn calculus 9.5
Renal abscess 9.4
Acute fatty liver 9.4
urosepsis 9.4
chronic cystitis 9.4
cystitis 9.4
cystopyelitis 9.4
Toxic nephropathy 9.3
hydropyonephrosis 9.3
Renal hemorrhage 9.3
Bacterial cystitis 9.3
recurrent cystitis 9.3
urinary tract infection during pregnancy 9.3
carbuncle 9.3
gouty nephropathy 9.3
Septic abortion 9.2
nephroptosis 9.2
pyuria 9.2
Reflux nephropathy 9.2
Renal pelvis 9.2
Renal pelvis 9.2
Primary vesicoureteric reflux 9.2
bladder infection 9.1
Renal tuberculosis 9.1
Polypoid cystitis 9.0
Disseminated mucormycosis 9.0
allergic reaction to penicillin 9.0
panmyelophthisis 9.0
chronic glomerulonephritis 9.0
chronic urinary tract infection 8.9
urinary tract infection 8.8
Renal infarction 8.8
perinephritis 8.7
Ureteritis cystica 8.6
SCCH 8.6
Functional asplenia 8.6
renal papillary necrosis 8.6
Chronic interstitial nephritis 8.6
ureterolithiasis 8.5
juxtaglomerular cell hyperplasia 8.4
Cross infection 8.4
urinary tract obstruction 8.4
Cervical erosion 8.3
recurrent urinary tract infection 8.3
Klebsiella bacteremia 8.3
Transient proteinuria 8.3
Abdominal lymphadenopathy 8.3
Salmonella enteritis 8.3
uropathy 8.3
urethral syndrome 8.1
ureterectasis 8.1
pyorrhea 8.1
hydronephrosis 8.1
nephrosclerosis 8.1
prostatitis 8.0
Mesangioproliferative glomerulonephritis 8.0
puerperal endometritis 8.0
cervicobrachial syndrome 7.9
ureterocele 7.9
nephrolithiasis 7.9
Renal cortical necrosis 7.9
Aspergillus endophthalmitis 7.9
Drug-induced immune hemolytic anemia 7.9
stage I testicular cancer 7.9
balanoposthitis 7.8
Acute respiratory distress 7.8
sponge kidney 7.8
HIV neuropathy 7.8
Stauffer's syndrome 7.8
Hepatic impairment 7.7
Disseminated aspergillosis 7.7
Salmonella sepsis 7.7
interstitial nephritis 7.6
Escherichia coli bacteremia 7.6
Ureteropelvic junction obstruction 7.6
Nodular glomerulosclerosis 7.6
urolithiasis 7.6
Xanthinuria 7.5
Staphylococcal sepsis 7.5
salpingo-oophoritis 7.5
renin-dependent hypertension 7.5
Miliaria crystallina 7.5
acute lymphadenitis 7.4
Urethral obstruction 7.4
E. coli septicemia 7.4
sigmoiditis 7.4
prostatic adenoma 7.4
Staphylococcus aureus meningitis 7.4
Metastatic adenocarcinoma 7.4
hydroureteronephrosis 7.4
Intra-abdominal abscess 7.3
renal artery obstruction 7.3
Salmonella bacteremia 7.3
paraphimosis 7.3
neurogenic bladder 7.2
Lymphangiosarcoma 7.2
Mucinous cystadenoma 7.2
metastatic Wilms' tumor 7.2
Renal metastasis 7.2
hyperchloremia 7.2
epididymitis 7.1
ureter 7.1
Escherichia coli pneumonia 7.1
UFS 7.1
Prostatic abscess 7.1
hypercupremia 7.1
Hyponatremic 7.1
Hypervitaminosis A 7.0
Transplant glomerulopathy 7.0
subphrenic abscess 7.0
more...
Symptom
CVA tenderness 10.5
nephralgia 10.3
prostatic tenderness 9.5
renal pain 9.1
Persistent vomiting 8.6
flank pain 8.3
UTI symptoms 8.3
unable to urinate 8.3
loin pain 8.2
side pain 8.2
renal colic 8.1
pneumaturia 7.5
Fetal bradycardia 7.3
dysuria 7.3
strangury 7.3
Kernig's sign 6.7
unable to conceive 6.7
Infantile colic 6.5
lumbar back pain 5.9
Overlying 5.9
clubbing 5.7
phosphatemia 5.6
hyperemesis gravidarum 5.6
hematocolpos 5.4
urinary frequency 5.2
prostatism 5.2
urethral discharge 5.1
nocturnal polyuria 5.1
right lower quadrant pain 5.1
colic 5.0
fever of unknown origin 5.0
chills 4.9
right upper quadrant pain 4.9
polyuria 4.8
enuresis 4.8
oliguria 4.8
Lower urinary tract symptoms 4.8
decreased appetite 4.5
emaciation 4.3
acute abdomen 4.2
dark urine 4.2
abdominal pain 4.0
meningism 3.9
polydipsia 3.8
prostration 3.8
hypoproteinemia 3.8
groin pain 3.8
bladder pain 3.7
acute abdominal pain 3.7
night sweats 3.7
back pain 3.6
stomach pain 3.4
hyperesthesia 3.3
ketonuria 3.2
Fluctuation 3.1
lethargy 3.0
nausea 3.0
tonic-clonic seizure 3.0
limb pain 2.9
vomiting 2.9
exertional angina 2.8
anorexia 2.8
diarrhea 2.7
rigors 2.7
livedo 2.6
nausea and vomiting 2.6
low back pain 2.5
pelvic pain 2.4
dry skin 2.4
constipation 2.3
respiratory distress 2.3
microbial colonization 2.3
muscle rigidity 2.3
Ill 2.2
cachexia 2.2
hypotonia 2.1
hypertonia 2.1
chronic constipation 2.0
discomfort 2.0
discomfort 1.9
arthralgia 1.8
bone pain 1.7
dizziness 1.7
torticollis 1.7
paresthesia 1.7
exertional dyspnea 1.6
hip pain 1.5
thinning 1.5
dysarthria 1.5
leg pain 1.3
twitching 1.3
blurred vision 1.3
pain 1.3
tense 1.3
dyspnea 1.2
splenomegaly 1.1
pallor 1.0
tachypnea 1.0
asthenia 1.0
ENT 1.0
regurgitation 0.9
shoulder pain 0.9
hepatomegaly 0.8
weakness 0.8
fatigue 0.7
tinnitus 0.7
epigastric pain 0.6
headache 0.6
angina 0.6
cerebellar ataxia 0.5
cough 0.4
agitation 0.4
anesthesia 0.3
apathy 0.3
collapse 0.3
myoclonus 0.3
hepatosplenomegaly 0.2
functional recovery 0.2
shortness of breath -0.0
hypothermia -0.2
hemoptysis -0.2
tremor -0.2
sleepiness -0.3
spasticity -0.3
myalgia -0.3
erythema -0.3
overweight -0.3
exhaustion -0.4
vertigo -0.5
spasm -0.5
acidity -0.5
ataxia -0.6
dystonia -0.7
analgesia -0.9
insomnia -1.0
seizures -1.6
Welt -1.6
Drug
Tetroxoprim 11.3
Parafon Forte 11.3
Monocid 10.8
Temafloxacin hydrochloride 10.3
Fosfomycin calcium 10.3
Equipalazone 10.0
Invanz 9.5
Kanamycin sulfate 9.5
Zymar 9.5
Tavanic 9.2
LFLX 9.2
Timentin 9.0
Cefroxadine 8.9
TFLX 8.8
Fosfomycin tromethamine 8.8
Amikin 8.8
DMSA 8.7
CZON 8.7
CMNX 8.5
Dalfopristin 8.4
Securopen 8.3
Amdinocillin 8.3
CEZ 8.1
Amikacin sulfate 8.1
Cefetamet 8.1
lomefloxacin hydrochloride 8.0
Cefuzonam 7.9
ENX 7.9
CFIX 7.9
Doripenem 7.9
FMOX 7.9
CMZ 7.8
CPDX-PR 7.7
Unasyn 7.3
LMOX 7.3
Temocillin 7.3
Cefmenoxime 7.3
Dibenzyline 7.3
Garamycin 7.2
Rocephin 7.2
CZX 7.1
CPFX 7.1
Tosufloxacin 7.0
CTRX 6.9
NFLX 6.8
Imuran 6.7
Sulfadimethoxine 6.7
Barium sulfate 6.6
Cefaclor 6.4
OFLX 6.4
Gatifloxacin 6.4
Sitafloxacin 6.4
Meropenem 6.3
Meropenem 6.2
CPFX 6.1
Drotrecogin alfa 6.1
SBT 6.0
Drotrecogin alfa 6.0
Ofloxacin 6.0
Ceftazidime 6.0
Ertapenem 6.0
CAZ 5.9
Inderal 5.8
AMK 5.8
Pefloxacin 5.7
CMX 5.5
Gemifloxacin 5.5
Plavix 5.4
Iopromide 5.3
Levovist 5.3
Augmentin 5.3
Augmentin 5.2
CPZ 5.0
CTM 5.0
Beta-2 5.0
Piperacillin 4.9
Bromelain 4.9
Amoxicillin 4.8
Artemether 4.8
Zinat 4.8
CrCl3 4.8
ampicillin 4.8
Estriol 4.6
Peridex 4.5
AMC 4.5
IPM 4.4
Voltaren 4.4
EMB 4.3
Nephron 4.2
Bestatin 4.2
CLS 4.2
PPA 4.1
CFT 4.1
NAG 4.1
NovoSeven 4.0
Vena 4.0
Vena 4.0
Dexon 4.0
DEL 3.9
Felodipine 3.8
Trimethoprim-sulfamethoxazole 3.8
CTT 3.7
Nephron 3.6
Tocilizumab 3.6
AZT 3.6
Fluconazole 3.6
CTX 3.6
CTX 3.6
CVA 3.5
ISP 3.5
Orion 3.4
DDAVP 3.4
DDAVP 3.4
Galactose 3.3
Coral 3.3
Antithrombin III 3.3
AraC 3.3
CTX 3.2
Helium 3.1
CFS 3.0
NBT 3.0
Isotretinoin 2.9
CIA 2.7
Tacrolimus 2.6
Photofrin 2.5
Itraconazole 2.4
Prednisone 2.3
Diphenhydramine 2.3
Clopidogrel 2.2
Lactose 2.2
Glycerol 2.2
Phentolamine 2.1
Fraction 2.0
Spectrum 1.9
Prednisolone 1.8
Sorafenib 1.8
Dial 1.7
Activin 1.6
Diurnal 1.6
Spectrum 1.4
Dakar 1.3
ACT 1.3
Paraffin 1.2
Captopril 1.2
Fragment 1.2
AZT 1.0
Alanine 0.9
ABC 0.8
Gel 0.8
IFN-beta 0.8
Vitamin A 0.8
CSF 0.7
IL-2 0.7
Retinoic acid 0.6
ROC 0.4
p75 0.4
lactose 0.3
ENT 0.3
Leaf 0.3
G-CSF -0.0
more...
Enzyme
alanine aminopeptidase 6.7
CPN 4.6
glutamic dehydrogenase 4.5
urease 4.5
CD13 4.4
urease 4.4
peptide deformylase 4.4
C3b inactivator 4.3
condensing enzyme 4.3
beta-lactamase 4.2
alanine racemase 4.0
CGT 3.5
TGT 3.3
fumarase 3.2
alpha-glucosidase 3.1
arylsulfatase A 3.1
PAH 3.0
malate dehydrogenase 3.0
alanine aminotransferase 3.0
glutathione synthetase 2.9
gamma-glutamyl transpeptidase 2.9
lysozyme 2.8
AGT 2.8
renin 2.7
MDH 2.7
MDH 2.6
prostate-specific membrane antigen 2.6
MDP 2.5
Pla 2.5
glutaminase 2.4
ceruloplasmin 2.4
bromelain 2.3
kallikrein 2.1
AST 2.1
MIP 2.1
tissue kallikrein 2.0
beta-glucuronidase 2.0
BMT 2.0
lactate dehydrogenase 2.0
chymase 2.0
neutrophil elastase 1.9
tryptase 1.9
transpeptidase 1.8
deoxyribonuclease 1.8
alpha-mannosidase 1.8
deoxyribonuclease 1.8
leucine aminopeptidase 1.7
PRA 1.6
dipeptidyl peptidase IV 1.6
xanthine oxidase 1.6
alpha-galactosidase 1.6
hexosaminidase 1.5
prolyl hydroxylase 1.5
prostaglandin synthetase 1.5
cathepsin K 1.5
alkaline phosphatase 1.4
caspase-1 1.3
matrix metalloproteinase 9 1.2
aspartate aminotransferase 1.1
DNase 1.0
demethylase 0.9
protein phosphatase 2A 0.8
elastase 0.8
thyroid peroxidase 0.7
peroxidase 0.7
sulfatase 0.7
CD10 0.7
ribonuclease 0.7
ribonuclease 0.6
UDP-glucuronosyltransferase 0.6
NADPH oxidase 0.6
urokinase-type plasminogen activator 0.5
carbonic anhydrase 0.5
NADPH oxidase 0.5
glucose-6-phosphate dehydrogenase 0.4
superoxide dismutase 0.4
APC 0.3
cathepsin B 0.3
heme oxygenase 0.3
MMP 0.3
calcineurin 0.3
acid phosphatase 0.3
pepsin 0.3
glutamate dehydrogenase 0.3
glutamate dehydrogenase 0.2
glutamate dehydrogenase 0.2
citrate synthase 0.2
ACE 0.2
catalase 0.2
beta-galactosidase 0.1
topoisomerase 0.1
adenosine deaminase 0.0
adenosine deaminase -0.0
alpha-amylase -0.0
phosphorylase -0.1
phosphoinositide 3-kinase -0.2
collagenase -0.2
endonuclease -0.3
lipase -0.3
creatine kinase -0.3
ornithine decarboxylase -0.3
caspase-8 -0.4
trypsin -0.4
phospholipase A2 -0.5
neuraminidase -0.5
ATPase -0.5
thymidine kinase -0.5
succinate dehydrogenase -0.7
RNase -0.7
RNase -0.8
topoisomerase -0.8
phospholipase C -0.8
phosphodiesterase -0.9
transcriptase -0.9
glutathione peroxidase -1.1
thrombin -1.1
RNA polymerase -1.2
cholinesterase -1.3
thromboplastin -1.4
NO synthase -1.6
reverse transcriptase -1.6
caspase-3 -1.8
MEK -1.8
mitogen-activated protein kinase -1.9
acetylcholinesterase -2.5
proteasome -2.5
ERK -2.6
protein kinase -4.0
Compound
Fosfomycin calcium 10.8
R 48 9.8
Kanamycin sulfate 9.3
Sulbenicillin 9.0
Cefroxadine 8.9
Dalfopristin 8.4
Complement factor B 8.2
Cinoxacin 8.1
Bacampicillin 8.1
Cefixime 7.8
Fleroxacin 7.6
HM-3 7.5
Hippuran 7.3
EDAP 7.2
C6H8O7 7.2
Dibenzyline 7.2
Aerobactin 7.1
Chlorhexidine diacetate 7.1
Tazobactam 7.0
Cefmetazole 7.0
Sulbactam 7.0
Nitrofurantoin 7.0
Netilmicin 7.0
Ceftizoxime 7.0
Sisomicin 6.9
Levofloxacin 6.9
Biapenem 6.8
Chlorhexidine diacetate 6.8
Sulfoxide 6.7
Aztreonam 6.6
Fosfomycin 6.6
Enterobactin 6.6
Ethylene dibromide 6.6
Cefpirome 6.6
Gatifloxacin 6.5
Ceftriaxone 6.5
3,4-dihydro-2H-pyran 6.4
Cefaclor 6.4
Cefonicid 6.4
Sitafloxacin 6.4
Ticarcillin 6.3
APN 6.3
Vinclozolin 6.2
Norfloxacin 6.1
Cefuroxime 6.1
Zingerone 6.1
Cefuroxime axetil 6.1
Tobramycin 6.0
Thiamphenicol 6.0
Ceftazidime 6.0
FANFT 6.0
GPT 6.0
Ofloxacin 5.9
TMP 5.8
Enoxacin 5.8
Quinupristin 5.8
Biuret 5.8
TMP 5.8
TMP 5.8
UPP 5.8
Gb4 5.7
cinnoline 5.7
pentitol 5.6
2,3-dimercaptosuccinic acid 5.6
Cefotetan 5.4
Cefotaxime 5.4
T 1 5.4
pentitol 5.4
Ciprofloxacin 5.3
TMP 5.3
pentitol 5.3
Gentamicin 5.3
Cefoxitin 5.2
Lomefloxacin 5.2
Amikacin 5.1
3GC 5.0
Bestatin 5.0
Piperacillin 5.0
Cefepime 4.9
Luminol 4.8
Cephalothin 4.8
CPZ 4.8
Amoxicillin 4.8
C56 4.8
Benzyl alcohol 4.8
acetohydrazide 4.8
Sparfloxacin 4.7
Candesartan 4.7
Triamcinolone acetonide 4.5
Triamcinolone 4.4
Caffeic acid phenethyl ester 4.4
NFA 4.4
creatinine 4.4
BRL 4.3
HfO2 4.2
Polymyxin B 4.1
Estriol 4.1
Mannose 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
carbonic acid 4.1
Imipenem 4.1
carbonic acid 4.0
D-glucaric acid 4.0
carbonic acid 4.0
Phenylbutazone 4.0
Fluvastatin 4.0
Cefazolin 3.9
PPA 3.9
Xanthine 3.9
DBM 3.8
DBM 3.8
Inulin 3.8
PIN 3.7
TGT 3.6
Xylitol 3.6
HIS 3.6
Fumarate 3.6
Kanamycin 3.6
carbonic acid 3.6
beta-Carotene 3.6
nonanoic acid 3.6
Zolpidem 3.5
EOS 3.5
Diazoxide 3.5
Allergan 3.4
FDP 3.4
MIC 3.4
Azathioprine 3.3
AME 3.3
Ifosfamide 3.3
carbonic acid 3.3
Galactose 3.3
Sudan I 3.3
PAP 3.3
B17 3.3
succinic acid 3.2
succinic acid 3.2
succinic acid 3.2
succinic acid 3.2
PAH 3.2
CTX 3.2
DTPA 3.2
Trimethoprim 3.1
Cytochalasin D 3.1
ANCA 3.1
STP 3.0
more...