Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034186 (
pyelonephritis
)
6,144
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We investigated the expression of
osteopontin
(
OPN
) messenger (m) RNA in the rat kidney under the experimental models of several conditions that are considered to be risk factors of human renal stones. In the renal stone formation model administrated glyoxylic acid and 1,25-dihydroxyvitamin D3,
pyelonephritis
model and hydronephrosis model the expression of
OPN
mRNA in the distal convoluted tubule of the kidney was enhanced compared with the control which was sporadically positive utilizing in situ hybridization and northern blot analysis. The expression of
OPN
mRNA was markedly inhibited in the renal stone formation model by concominant administration of estradiol and/or progesterone.
...
PMID:Expression of osteopontin messenger RNA in the rat kidney on experimental model of renal stone. 773 36
