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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two generations of one family with Alport syndrome were studied. The observation proved that women do transmit the disease, but men have signs more developed. As symptoms of the disease were pathological changes of chronic interstitial haemorrhagic pyelonephritis associated with bilateral hearing loss of cochlear type. In patients with pronounced hearing impairment (in the spiral organ) the kidney pathology was not advanced and the course of the illness rather mild. We believe that patients with kidney pathology should have their hearing examined as routine proceeding because hearing impairment is frequently associated with kidney pathology as in Alport's syndrome and other diseases. This coincidence may help in diagnosis, choice of treatment and prognostic evaluation.
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PMID:[Chronic hereditary nephritis with hearing loss (Alport's syndrome)]. 264 Apr 96

The histologic picture in the kidney in Alport syndrome varies (later lesions resemble glomerulonephritis, pyelonephritis, or interstitial nephritis), and the site of the initial renal lesion is uncertain. We have observed marked characteristic ultrastructural changes in the basement membranes of glomerular capillaries, even when few abnormalities were seen in the kidney by light microscopy. Their cause is unknown. There was no significant evidence that immune complexes, fibrin, or viruses were factors in their pathogenesis.
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PMID:The pathology of the kidney in the Alport syndrome. 447 Aug 85

Virtually all diseases affecting the native kidney recur in the kidney transplant with the exception of Alport syndrome, polycystic kidney disease, hypertension, chronic pyelonephritis, and chronic interstitial nephritis. Fortunately, in the majority of patients, recurrence of the original disease has minimal clinical impact, with only approximately 5% of all graft loss occurring as a result of recurrent disease. The primary renal diseases that commonly recur include membranoproliferative glomerulonephritis type II, IgA nephropathy, and focal and segmental glomerular sclerosis. The most common systemic disease that recurs is diabetic nephropathy. Living-related transplantation should be used with caution in patients with the hemolytic uremic syndrome, recurrent focal and segmental glomerular sclerosis, and membraneous glomerulonephritis. Fabry disease and primary hyperoxaluria type I are no longer absolute contraindications to kidney transplantation.
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PMID:Recurrent diseases in the kidney transplant. 802 19