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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 85 patients with ascertained chronic pyelonephritis the relations between the measured values of the combined PAH-inulin-clearance, the index of the adrenal cortex and other radiological findings were investigated. Here the determination of the cortex of the adrenal cortex resulted in a better correlation with the sizes clarification values than the calculation of the size of the kidney. By variance analysis (F-test) significant differences between the individual function groups became clear.
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PMID:[Relationships between the value of combined PAH-inulin clearance, the kidney-cortex index as well as between additional radiographic findings in chronic pyelonephritis]. 59 10

The authors report on their 9-year experience concerning the results of the determination of the effective plasma flow by means of the 131J-hippuran clearance in patients with chronic pyelonephritis. On account of the disagreements in literature it was our first task to establish the lower normal limit. Issuing form the parallel investigations with the classical PAH-clearance in 50 patients and in a control group of 71 patients with hearlhy kidneys 487 ml/min were taken into consideration as lower normal limit. The authors examine in 867 patients with chronic pyelonephritis whether it is possible to diagnose relatively early disturbances of the renal function in values of the hippuran clearance lower than 487. It was established that in 28.9% of these patients the ING was normal, in 45% the concentration power maintained and in 70% the rest nitrogen in the serum was not increased. These results allow the recommendation of a broader application of the hippuran clearance in patients with pyelonephritis, since by means of this method relatively earlier restrictions of the renal function can be established than by means of other functional tests (ING and Volhard's test).
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PMID:[Diagnostic value of the 131 I-hippuran clearance in chronic pyelonephritis]. 84 43

On account of the solution of the problem, whether already after a four weeks' therapy with antibiotics in chronic progressing pyelonephritis a measurable increase of function may develop, the combined PAH-inulin-clearance was performed 35 times. 9 patients did not show a clear restriction of the clearance, wherefore in these cases a control examination was not necessary. In 10 patients of 12 an increase was present, in 7 patients a significant increase of the renal function existed after the therapy carried out. Therefore already after antibiotic impact therapy in patients with chronic pyelonephritis without provable acute episode an improvement of the function can occur, which is to be increased or kept by means of the long-term treatment.
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PMID:[Measurement of kidney function using combined PAH-inulin clearance before and after bactericide treatment of chronic pyelonephritis]. 118 97

Felodipine, a dihydropyridine calcium antagonist, was used to treat eight patients with severe uncontrolled hypertension: five had essential hypertension, two had renovascular disease, and one chronic pyelonephritis. Mean blood pressure (BP) was 221 +/- 14/120 +/- 4 mm Hg despite treatment with three or more antihypertensive drugs. All patients experienced an immediate and pronounced lowering of BP after adding felodipine, which persisted during long-term treatment in combination with previous medication except for vasodilating drugs. In all cases, an increase in glomerular filtration rate (51Cr-EDTA clearance) after 6 and 12 months of felodipine treatment was seen (59 +/- 10 to 63 +/- 7 and 70 +/- 6 ml/min, respectively, p less than 0.05). Renal plasma flow (PAH clearance) exhibited only a slight increase (315 +/- 68 to 340 +/- 63 and 314 +/- 69 ml/min), giving a nonsignificant rise in filtration fraction (18 +/- 1 to 21 +/- 1 and 20 +/- 1%, respectively). It is concluded that felodipine decreases BP dramatically in patients with previously refractory hypertension and that the drug causes an improved renal function in these patients.
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PMID:Long-term effects of felodipine on blood pressure and renal hemodynamics in severe hypertension. 169 10

In 15 children 2 months to 5 years after a transplantation of a cadaver kidney the renal function was determined by means of a clearance- and Tm-PAH-examination. Only in 4 children the Tm-PAH reached the normal value of a kidney. The calculation of the glomerulo-tubular balance results in increased values. The result for the relative tubular blood supply is normal. Compared with the values of children with an overcome haemolytic-uraemic syndrome or with a chronic glomerulonephritis or pyelonephritis shows that the renal function in children who underwent a transplantation similarly behaves as in a chronic pyelonephritis.
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PMID:[Initial results of tm-PAH studies in children with kidney transplants]. 355 89

Renal processing of insulin was studied over plasma insulin levels of 5-80 mU/l by renal vein catheterization in 14 patients. Kidneys of patients with a normal GFR removed around 30% of the insulin from arterial plasma. In 6 patients having unilateral renal artery stenosis but only moderately impaired renal blood flow and unchanged PAH-extraction, a higher or unchanged fractional insulin extraction was seen in all but one, compared with the contralateral kidney. Due to the high fractional extraction of insulin by the kidneys with renal artery stenosis, a preserved total insulin uptake by these kidneys was seen. In 4 patients with renal hypoplasia (2 of them had renal artery stenosis) low values for insulin extraction and insulin uptake were seen on the affected side. One patient with chronic pyelonephritis and uremia had an extremely low renal insulin extraction and uptake. The results suggest that estimation of renal insulin extraction may be an important renal functional test in renovascular patients.
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PMID:Renal degradation of insulin in patients with renal hypertension. 634 75

In an attempt to elucidate the reduced concentrating capacity in acute pyelonephritis, we studied the renal function in 14 children, 5 to 16 years of age. Clearance of inulin, PAH, and free water, urinary sodium excretion, and maximal urine osmolality after 18 hours of thirst have been determined at and within 10 months after infection. Glomerular filtration rate and renal plasma flow were found to be increased during infection and normalized after infection. Urinary sodium excretion, distal sodium delivery, and maximal urine osmolality were decreased during infection and increased afterwards. Kidney size was also increased during infection. It is postulated that the reduced concentrating capacity is due to a washout effect mediated by an increased medullary blood flow and to a low distal tubular sodium delivery.
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PMID:Renal function in acute febrile urinary tract infection in children: pathophysiologic aspects on the reduced concentrating capacity. 733 47