Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The rhesus monkey (Macaca mulatta) proved to be a successful model for the ultrastructural study of ascending nonobstructive pyelonephritis. The most severe kidney damage occurred where the inflammatory response was greatest, and these areas overlaid a dilated or clubbed calyx. The most prominent ultrastructural changes were in the renal tubular cells that showed swollen mitochondria with ruptured inner membranes, dilated endoplasmic reticulum, and flocculent and irregular basal laminae. No recognizable bacterial structures were seen.
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PMID:Chronic pyelonephritis. An electron microscopic study in nonhuman primates. 10 81

Bromadiolone damaged the erythrocytes, resulting in a probable saturation of transferrin, a deposit of iron in the connective tissue and in a few cells of the proximal tubules of the kidneys and an increased storage of ferritin in the spleen. In the hepatocytes, mitochondria were distorted, their lipid inclusions being granular; a large depletion of glycogen may be considered a reflection of an elevated phosphorylase a ascribable to the proliferation of the smooth endoplasmic reticulum. In the kidneys, pyelonephritis may be irrelevant to the poisoning of the animals. Bromine could not be detected using microanalytical methods.
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PMID:[Effects of bromadiolone on some organs and tissues (liver, kidney, spleen, blood) of coypu (Myocastor coypus)]. 190 55