Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report the results of clinicopathological and histochemical studies on 64 renal adenomas found in 22 patients. We selected typical renal adenomas for these studies, discarding borderline lesions. The ages of the patients ranged from 42 to 84 years, with an average of 61 years. Male to female sex ratio was 6.3:1. The background conditions included renal cell carcinoma, long-term dialysis, chronic glomerulonephritis, pyelonephritis, hydronephrosis and polycystic kidney. The sizes of the tumors ranged from 0.1 to 2.3 mm in maximum diameter, with an average of 0.9 mm. All the tumors were located in the cortex, especially in the superficial one-third. The cytoplasm of the tumor cells was predominantly eosinophilic, and the tumor structure was predominantly papillary. Histochemical study of 19 adenomas from 13 patients demonstrated that all of the adenomas from 13 patients demonstrated that all of the adenomas were positive for EMA, and for at least one marker of the distal tubulus, i.e., DBA, PNA, SBA and PKK1, and that 9 adenomas were positive for at least one marker of the proximal tubulus, i.e., LM1 and LTA. Renal adenomas had predominant histochemical features of the distal tubulus, suggesting differentiation to a distal tubulus-like histology.
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PMID:Renal adenoma. Clinicopathological and histochemical studies. 261 60

Beta-hemolytic Streptococcus agalactiae serotype V was identified as the cause of an infection in laboratory mice. Principally, the organism induced fatal septicemia in DBA/2 breeding-age mice. The syndrome appeared to originate as an ascending pyelonephritis, which progressed to septicemia. Microscopic lesions were found in the heart, kidneys, spleen, and liver, and less commonly in the uterus, thoracic cavity, lymph nodes, and lungs. The epizootic was controlled by eradication of the breeding colonies, disinfection of the barrier, and autoclaving of all equipment. The new replacement colonies have remained free of the organism.
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PMID:Epizootic of group B Streptococcus agalactiae serotype V in DBA/2 mice. 951 86