Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Polypoid cystitis, pyelonephritis, and obstructive uropathy was found in a cow with hematuria, dysuria, and colic. The cow was treated with penicillin, multiple B vitamin supplementation, and isotonic sodium chloride. Polypoid cystitis, diagnosed in this cow by use of endoscopic examination, is a common response to chronic inflammation of the bladder and can lead to obstructive uropathy. Although endoscopic confirmation of this diagnosis may not always be feasible, recognition of corresponding clinical signs can allow timely, appropriate treatment.
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PMID:Polypoid cystitis, pyelonephritis, and obstructive uropathy in a cow. 225 47

In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively. These differences depended on the expression of the basic (alkaline) characteristics of the anions of the administered solutions of potassium and sodium and the osmolarity of the administered amount of liquid. Pronounced ion exchange reactions were observed during the administration of KHCO3 solution only, the multiplicity factor of the excretion of sodium and chlorine ions with urine significantly exceeding that of diuresis. During the administration of KCl solutions in the isotonic NaCl solution and 5% glucose, the excretion of sodium and chlorine ions changed strictly in accordance with the changes of diuresis. Similar changes were noted in the administration of the solutions of sodium hydrocarbonate and sodium chloride.
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PMID:[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension]. 632 82

Inability to attain Umax after overnight dehydration is the earliest functional abnormality in human and experimental pyelonephritis caused by diverse microorganisms. In order to characterize the defect in Umax in experimental enterococcal pyelonephritis, another index of renal concentrating ability. TcH2O, was determined during saline loading. Normal TcH2O depends on adequate sodium chloride delivery and reabsorption in the ascending limb of Henle's loop and water reabsorption from the collecting duct. Rats with early pyelonephritis, 3 days after intravenous injection of enterococci, were compared with normal rats in studies of Umax during hydropenia and TcH2O during 1.2% saline infusion. Mean Umax in infected rats was significantly lower than in uninfected rats (1120 vs. 2767 mOsm/kg H2O) (p less than 0.01), but CIn in infected rats was not significantly different from that in uninfected rats (0.96 vs. 0.89 ml/min per 100 gm) (p less than 0.05). During saline diuresis, maximal Cosm/CIn was more than 35% in both the normal and infected rats. The relationship between TcH2O/CIn and Cosm/CIn was linear in both groups, and the r, slope, any y intercept of the regression equation of TcH2O/CIn vs. Cosm/CIn in infected rats were not significantly different from those in normal rats. During saline diuresis the regression of sodium excretion UNaV/CIn) vs. Cosm in infected rats was not significantly different from that in control rats. The finding of normal TcH2O during saline loading suggests that reabsorption of increasing amounts of sodium chloride from the ascending limb of Henle's loop and reabsorption of water in the collecting duct are normal in early pyelonephritis.
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PMID:Free water reabsorption during saline diuresis in experimental enterococcal pyelonephritis in rats. 706 23

A 68-year-old female on two-year chronic hemodialysis for chronic renal failure due to chronic pyelonephritis, was admitted to hospital for weakness, dulled sensorium and dizziness. On examination the patient was in a state of circulatory collapse, the electrocardiogram showed an accelerated idioventricular rhythm and laboratory analysis revealed extreme hyperkalemia (K+ 10.1 mmol/l). There were no common causes of shock, such as hypovolemia, sepsis, heart failure and presence of vasodilator drugs. The patient was treated with calcium gluconate, sodium bicarbonate and sodium chloride (to oppose the effects of hyperkalemia on the cell membrane to minimize cardiac and neuromuscular toxicity), insulin and dextrose (to increase the transport of K+ from the extracellular to the intracellular compartment), and hemodialysis (to remove K+ from the body). At the end of the hemodialysis session, the patient was in a clinically good condition, blood pressure was 160/90 mm Hg and the serum K+ concentration was normal. The case appeared to suggest that extreme hyperkalemia may have direct effects on vascular resistance, causing hypotension and shock.
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PMID:A life-threatening complication of extreme hyperkalemia in a patient on maintenance hemodialysis. 748 41

The authors have developed combined therapy of secondary chronic pyelonephritis with immune and urodynamic dysfunctions. The treatment includes physical factors: decimeter microwaves, gangleron-electrophoresis with sinusoidal modulated currents, sodium chloride baths, oral mineral water Moskovskaia. The adjuvant use of the above physical factors proved advantageous.
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PMID:[Physical factors in the therapy of secondary chronic pyelonephritis]. 784 80

The action of indirect electrochemical blood oxidation with 0.06% solution of sodium hypochlorite on kidney and urinary inflammation was studied in experiments on 60 non-inbred rat females of 200-250 g body weight. The animals were intravesically infected through the catheter with E. coli and Ps. aeruginosa. 3 days later, after histological verification of acute pyelonephritis, ureteritis, cystitis, the animals were injected intraperitoneally 1.0 and 2.0 ml daily of sodium hypochlorite solution (control animals) or 0.89% solution of sodium chloride. Though no reliable decrease of the bacterial contamination was achieved, histologically, there was a marked reduction in morphological signs of the inflammation in the kidneys, ureter and urinary bladder on the first day after beginning of electrochemical blood oxidation with solution of sodium hypochlorite in experimental groups. In experimental group rats morphological signs of urinary and renal inflammation for both infections disappeared on days 7 and 10, respectively. In the control animals morphological signs of the inflammation remained after 10 days. Moreover, purulent inflammation was registered in the controls infected with Ps. aeruginosa.
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PMID:[Effects of indirect electrochemical blood oxidation by sodium hypochlorite solution on the course on inflammatory process in the kidneys and urinary tract]. 964 85