Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Home intravenous antibiotic programs (HIAP) have been in existence for more than 12 years. The feasibility of such a program at the UBC-HSCH was assessed. The health records of all patients discharged between April 1, 1985 to March 31, 1987 with a diagnosis of septic arthritis, osteomyelitis, pyelonephritis, skin and soft tissue infections in the diabetic, prostatitis or infective endocarditis were reviewed retrospectively. Selection criteria to determine eligibility of patients for a HIAP were derived from the literature and grouped into three areas: patient, disease, and treatment criteria. From a total of 184 patients identified, 14 diabetic patients were excluded. The exclusion of patients with hospital stays of less than five days or those that did not have the appropriate diagnosis resulted in 77 patients available for more extensive review. Sixteen of 77 patients (20.8%) were judged eligible for a HIAP: 1 of 22 with pyelonephritis; 4 of 12 with septic arthritis; 5 of 21 with prostatitis; 2 of 12 with infective endocarditis; 4 of 10 with osteomyelitis. A total of 81 hospital bed days ($20,250.00) might have been saved if a HIAP was in place.
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PMID:Assessment of the need for a home intravenous antibiotic program. 1029 54

1. A growing range of infections can be safely and effectively treated with parenteral antimicrobial therapy at home, including cellulitis, pyelonephritis, pneumonia, endocarditis, osteomyelitis, septic arthritis and deep abscesses. 2. Patients may be admitted to HITH directly from the emergency department or after a period of in-hospital care; they must be thoroughly assessed for suitability, including clinical stability and social circumstances, and both patient and carer consent must be obtained. 3. Patients should be medically reviewed weekly at the hospital to monitor progress of therapy and check for possible complications, including adverse drug reactions. 4. Antibiotic selection should be based on appropriate prescribing principles rather than purely dosing convenience. 5. Innovative dosing regimens, including once-daily aminoglycosides, continuous-infusion beta-lactams (eg, flucloxacillin), once- or twice-daily cephalosporins (eg, cephazolin) and oral fluoroquinolones (eg, ciprofloxacin) provide effective therapy for a wide range of infections that would have previously required in-hospital care. 6. Appropriate use of HITH leads to improved patient and carer satisfaction, efficient in-hospital bed use and possibly some financial efficiencies. Not all patients receiving intravenous antibiotics need to be in hospital
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PMID:5: Hospital-in-the-home treatment of infectious diseases. 1205 99

Melioidosis is caused by the gram-negative environmental saprophyte, Burkholderia pseudomallei (B. pseudomallei). Common presentations include pneumonia, bone and joint disease, renal and soft tissue infections. However, head and neck involvement is rare. We report a jugular lymphnode abscess associated with facial percutaneous inoculation of B. pseudomallei. Hospital course was complicated by endocarditis, septic arthritis and pyelonephritis. Surgical drainage and intensive and eradicative phase of antibiotics successfully cured the disease.
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PMID:Jugular Lymphadenitis as a Precursor to Burkholderia Pseudomallei Sepsis. 3280 30


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