Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Inflammatory pseudotumor (IPS) of the urinary bladder was first described in 1980. We report four cases of IPS which occurred during the last four years. One tumor occurred in the bladder of a 49-year-old woman five months after abdominal hysterectomy of uterine leiomyomas, two tumors in a 35- and 39-year-old woman, respectively, without antecedental surgical intervention (though one with recidive after six months). The fourth occurred in a 64-year-old male in the proximal ureter by pyelonephritis. Two cases were initially diagnosed at frozen section during operative treatment, the others on paraffine section after immunohistochemical examination. Two cases showed an aberrant expression of cytokeratines. There is no evidence of recidive tumor within a mean follow up of 25 months (12-49 months). Features to differentiate benign from malignant spindle cell lesions of the lower urinary tract are the absence of atypical mitoses, significant cytologic atypia, absence of necroses within the tumor (rather on its surface), no destructive growth at the tumor margins and low cellularity. Usually, IPS show a submucosal edematous area with a deeper, highly cellular component. The clinical history of a recent bladder operation or gynecologic surgery is of upmost importance in making the diagnosis of IPS. Complete surgical excision, either by transurethral resection or partial cystectomy appears to be curative for IPS.
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PMID:Inflammatory pseudotumor of the ureter and the urinary bladder. 952 Oct 18

Inflammatory pseudotumor (IPT) is a pseudoneoplastic lesion that most commonly involves lung. We report a case of IPT of kidney associated with hepatocellular carcinoma. CT and PET/CT showed the features of renal cell carcinoma. After radical nephrectomy, histologic examination demonstrated acute pyelonephritis associated with papillary necrosis, and IPT involving renal parenchyma and capsule. Although renal IPT is a very rare tumor, awareness of its existence in the differential diagnosis of a renal mass is critical to avoid misdiagnosis. Clinician should carefully consider differential diagnosis and complications associated with acute or chronic pyelonephritis and papillary necrosis in diabetic patients, particularly.
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PMID:Inflammatory pseudotumor of the kidney mimicking malignancy on 18F-FDG PET/CT in a patient with diabetes and hepatocellular carcinoma. 2269 19