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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a retrospective study we found an increased incidence of E. coli septicemia and pyelonephritis among children cared for in a special neonatal ward during 1975 and 1976 compared to the following years. The study was undertaken because of a previously reported epidemic outbreak of E. coli pyelonephritis in children cared for in the same neonatal ward during 1979-1982. The increased incidence of infections seems to be caused by spread of one or several virulent E. coli strains in the ward. Two of the strains causing septicemia were saved. They showed a multiply resistant antibiotic pattern similar to most of the strains causing pyelonephritis among the children born at that time. Their serotype was O4:K3 and they were P-fimbriated. Septicemia occurred among high-risk infants at a mean age of five days, while pyelonephritis occurred among uncomplicated cases at a mean age of 3.9 months. The proposed spread of one or several virulent E. coli strains correlates to a high bed occupancy in the ward during that time. r = 0.38 (p less than 0.01).
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PMID:Epidemiological aspects of P-fimbriated E. coli. II. Variations in incidence of E. coli infections in children attending a neonatal ward. 287 Jun 1

The incidence of E. coli pyelonephritis before the age of one year among the children born at Danderyd Hospital during a ten year period was studied. During the study period, 4 or 5 outbreaks of E. coli pyelonephritis occurred among the children who had previously been staying in the hospital's neonatal ward. These outbreaks seemed to have been caused by nosocomial spread of and fecal colonization with certain virulent E. coli strains among the children staying in the ward during certain periods of time. The strains that were spread in the ward seemed to belong to certain pyelonephritogenic E. coli clones of the serotypes O6:K5, O4:K3 and possibly O6:K2. Although the children became fecally colonized with the strains in the neonatal ward, most fell ill some time after they had left the ward. The mean age at the development of their first pyelonephritis was 3.4 months for the boys and 6.2 months for the girls, who had been cared for in this ward. A correlation between the number of infections and the bed occupancy of the ward could be found (p less than 0.01). The risk for a child staying in the ward during an outbreak to develop pyelonephritis was about 5-10%. There was a baseline incidence rate of 0.6-0.7% during non-epidemic periods. During one of the outbreaks there was also an increased incidence rate of E. coli septicemia among the children staying in the neonatal ward. The predictive value of fecal colonization with P-fimbriated E. coli for the later development of extraintestinal E. coli infections was studied in a 2.5 year prospective study. During this study period there was a baseline incidence rate of 10-20% fecal colonization with P-fimbriated E. coli among the children staying in both the neonatal and maternity wards, interrupted only by minor peaks of colonization with such strains. Length of stay in the neonatal ward and a high bed occupancy of the neonatal ward were statistically correlated to fecal colonization with P-fimbriated E. coli strains (p less than 0.01). During the prospective study there was no difference in the incidence rates of pyelonephritis before the age of one year between the neonatal and maternity ward children. These incidence rates were 0.59% and 0.66%, respectively. Only one of the 113 children from the neonatal ward who were fecally colonized with P-fimbriated E. coli strains later developed pyelonephritis. Thus, there was no predictive value of fecal colonization with P-fimbriated strains for the later development of pyelonephritis.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:Fecal colonization with P-fimbriated Escherichia coli in newborn children and relation to development of extraintestinal E. coli infections. 288 17

Emphysematous escherichia coli endophthalmitis occurred in a 72-year-old patient as a complication of E. coli septicemia secondary to emphysematous pyelonephritis and endocarditis. This is the first reported case of endogenous emphysematous endophthalmitis secondary to E. coli septicemia.
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PMID:Escherichia coli emphysematous endophthalmitis and pyelonephritis. Case report and review of the literature. 327 76