Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The antibody amounts and avidities were analyzed in 13 patients with acute primary pyelonephritis, 11 patients with acute primary cystitis, and one with ureterocele and recurrent infections, using the ammonium sulphate precipitation (ASP) technique. The ASP titrations did not discriminate as well between pyelonephritis and cystitis as do the determinations with the indirect hemagglutination technique. The increase of antibody titer and avidity detected by the ASP method in some of the cystitis patients suggested a deeper tissue involvement in some cases resulting in antibodies demonstrable with this technique. Since control patients also showed a somewhat heterogenous antibody response regarding titer and avidity it cannot be excluded that stimulation by Escherichia coli antigens in the gut is detected by the ASP method.
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PMID:Amount and avidity of antibody to Escherichia coli O antigen measured with the ammonium sulphate precipitation technique in children with urinary tract infections. 110 May 27

The authors describe results of transurethral endoscopic treatment of ureterocele in 61 patients, two techniques of a relevant operative intervention, indications, complications of an early (pyelonephritis) and late (vesicoureteral reflux) postoperative period, measures of their prevention. Advancing impairment of the urine outflow via the upper urinary tracts on ureterocele side necessitates earlier surgery (transurethral dissection or resection of ureterocele). Good 4-year follow-up results (normal function of the kidney, absence of pyelonephritis attacks and vesicoureteral reflux) suggest endoscopic transurethral treatment of ureterocele to be a method of choice the failure of which implies open surgical intervention.
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PMID:[The endoscopic transurethral treatment of ureterocele]. 182 89

The method of diagnosis and therapeutic rules for pathological ureteral duplicity has been highly developed over the last few years. Recent advances in fetal ultrasonography sometimes allow an early diagnosis of renal or intravesical cystic structure to be appraised before complications (urinary tract infection or pyelonephritis, prolapsed ureterocele, recurrent orchitis, primary diurnal and nocturnal urinary incontinence with conserved micturation for a young girl). However, the basis of therapeutic rules remain unchanged, the superior pyelocaliceal system is not preserved in most cases of ureterocele with ureteral duplicity or ectopic ureter, because of major cystic dysplasia; although, in some cases when an earlier diagnosis is made, conservative treatment (primary endoscopy followed by a surgical intervention if necessary) can be proposed. Likewise, the endoscopic injection of Teflon causes the vesico-ureteral reflux to disappear in most cases (70%).
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PMID:[Development of the diagnosis and treatment of pyelo-ureteral duplication in children. Reflections on 179 cases]. 215 57

We analyze the results achieved by extracorporeal piezoelectric lithotripsy (EPL) in 40 renal units with the following anatomic anomalies: solitary kidney (10), chronic pyelonephritis (8), medulospongiosis (6), caliceal diverticula (5), intrarenal cysts (5), pyeloureteric duplicity (3), megacaliosis (1), horseshoe kidney (1), and ureterocele (1). Adequate stone fragmentation was achieved in 80% of the patients with solitary kidney; 20% developed obstructive complications (1 patient with a 15 mm.-stone and 1 patient with obstruction of double-J catheter). At 6 months, stone remnants persist in 71.4% (5/7) after stone fragmentation in those cases with pyelonephrosis. The rates for fragmentation, elimination of remaining stone fragments, and disappearance of pain are 80%, 50% and 100% for diverticular caliceal calculi, and 67%, 50% and 100% for those in kidney with medulospongiosis. We can conclude that placement of a double-J catheter is useful before EPL in patients with solitary kidney and calculi greater than 10 mm. EPL is the first therapeutic approach in symptomatic lithiasis in caliceal diverticula or precaliceal cystic dilatation (medulospongiosis).
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PMID:[Efficacy and limitations of piezoelectric extracorporeal lithotripsy in kidneys with anatomical abnormalities]. 238 48

A case is reported of a large left ureterocele in a duplicated system at the expense of the upper renal pelvis. This ureterocele caused acute pyelonephritis and dilatation of both left systems. It was treated by a classic endoscopic incision of its roof but 18 months later, infecting vesico-renal, grade 2, reflux was developed. This secondary reflux was treated successfully by submeatal polytetrafluoroethylene's (Teflon) paste injection. This new combination of endoscopic techniques proved to be available in this case.
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PMID:[The possibilities of endoscopy in the treatment of various childhood ureteroceles. Apropos of a case]. 238 5

Pharmacokinetics and characteristic features of ampicillin kidney distribution were studied in 21 children with chronic pyelonephritis without signs of renal insufficiency who had undergone urological operations. It was found possible to provide the antibiotic concentrations efficient against ampicillin sensitive and partially middle sensitive microorganisms in the renal parenchyma, pelvis wall, ureterocele, megaureter and urinary bladder. Ampicillin concentrations in tissues of the urinary system were shown to correspond to a higher extent to the concentrations attained in blood than those in urine.
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PMID:[Characteristics of intrarenal ampicillin distribution in chronic pyelonephritis in children]. 331 89

The ectopy of the ureter orifices and ureterocele are always followed by either mechanical or dynamic obstruction of the ureter and obstructive pyelonephritis. These anomalies are periodically accompanied by abdominal pains which make their appearance during an attack of acute pyelonephritis. These abdominal pains can be erroneously taken for symptoms of appendicitis or intestinal obstruction and the patients are subjected to appendectomy or laparotomy by mistake. The erroneous appendectomy or laparotomy were fulfilled in 47 of 201 patients with ectopy of ureter orifices and ectopic ureterocele which were observed by the authors. The differentiation of genesis of abdominal pains may be more exact with the help of chromocystoscopy, excretory urography and isotopic renography.
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PMID:[Anomalies of ureteral orifices simulating diseases of the abdominal organs]. 367 20

The clinical and pathological findings in 150 children submitted to partial or total nephrectomy have been reviewed. Histological examination of the kidney removed at operation showed evidence of renal dysplasia in 76 (51%). These 76 patients were divided into three main groups on the basis of the pathological changes found in the kidney and the associated urinary tract anomalies. In group 1, gross cystic renal dysplasia was associated with absence or atresia of the renal pelvis and ureter. In group 2, renal dysplasia was segmental; the ureter, although patent, had some anatomical or functional abnormality which resulted in urinary stasis or reflux. In many of these patients dysplasia was confined to the upper pole of a ;duplex' kidney which was drained by an ectopic ureterocele. In group 3, renal dysplasia was associated with obstruction of the lower urinary tract, most commonly by posterior urethral valves. In group 1 dysplasia was total, involving the whole kidney, whilst in groups 2 and 3 dysplasia tended to be segmental; in the majority some normal renal tissue was present. Pyelonephritis was a very common complication, but was present only in patients from groups 2 and 3, in whom a lumen was present in the draining ureter, and not in patients from group 1 in whom the ureter was atretic or absent, and the kidney not functioning. It appears that urinary obstruction, stasis, or reflux are the principal factors predisposing to and promoting pyelonephritis in dysplastic kidneys. There seems to be no reason to suppose that dysplastic renal tissue is abnormally susceptible to infection since pyelonephritic changes were lacking in those cases in which dysplasia was most severe.
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PMID:Renal dysplasia. I. A clinico-pathological study of 76 cases. 557 4

It has been postulated that in some patients with obstructive and reflux uropathy proteinuria develops through an intermediate mechanism of immune complex glomerulonephritis involving antigenic material of renal tubular epithelium. A patient with a unilateral ureterocele and nephrotic syndrome underwent bilateral renal biopsies during surgical correction of the obstruction. The obstructed kidney showed mild pyelonephritis, but both kidneys showed a glomerulopathy with electron-dense deposits in the mesangial and paramesangial regions associated with positive immunofluorescence for immunoglobulin M (IgM) and the third component of complement (C3). An IgM antibody was eluted from the biopsy specimens and it reacted by indirect immunofluorescence with normal renal tubular epithelium and with the patient's renal tubular epithelium. The eluate also reacted with pre-eluted glomeruli of the patient, but not with normal glomeruli. All antibody activity could be removed from the eluate by pre-incubation with normal kidney. It is concluded that the unilateral renal obstruction produced tubular injury so that as yet unidentified antigens were recognized by the immune system. The resultant antibody response gave rise to circulating immune complexes which were then deposited in glomeruli with subsequent glomerular damage and nephrotic syndrome.
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PMID:Demonstration of an antibody to tubular epithelium in glomerulonephritis associated with obstructive uropathy. 700 83

The surgery is made to save both halves of the double kidney in mechanic obstruction or vesicoureteral reflux in the accessory or basic ureter. The affected ureter is always removed under anastomosis. The interventions are indicated in anomalies causing ureteral obstruction, ureterohydronephrosis, vesicoureteral reflux, pyelonephritis. They are frequently performed in ectopic ureterocele of the accessory ureter, in vesicoureteral reflux associated with intravesical high ectopy of the basic ureter ostium and normal ostium of the accessory ureter, in low intra- and extravesical ectopy of the accessory ureter ostium. The authors have conducted 21 operations in 20 patients: bilateral transureteroureteral, 2 intrapelvic, 1 ureteropelvic and 18 transureteroureteral anastomoses. The surgery was decided upon because of ectopic ureterocele of the accessory ureter, ectopic ureterocele of the accessory ureter with vesicoureteral reflux via ureterocele, high ectopy of the basic and low ectopy of the accessory ureter ostia with reflux, low ectopy of the accessory ureters ostia. Short- and long-term outcomes of all the operations were good.
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PMID:[Interpelvic, ureteropelvic and interureteral anastomoses in duplication of the kidney and the ureter]. 773 34


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