Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of the current investigation was to evaluate practical impact of modern NCCLS recommendations for the selection of 2nd and 3rd generation cephalosporins in Moscow teaching multi profile hospital. The sensitivity of clinically significant 96 strains from patients with pyelonephritis and 180 strains from patients with lower respiratory tract infections (pneumonia, COPD) was compared for cefuroxime and cefotaxime or ceftriaxone according NCCLS recommendations during 2000-2001 years. At the lower respiratory tract infection total sensitivity of all pathogens was 70.6% and 72.8%, at the pyelonephritis 71.9% and 76.0% for 2nd and 3rd generations respectively. The differences between cephalosporins were not statistically significant. Based on the application of modern NCCLS recommendations in the routine microbiological practice similar clinical efficacy of 2nd and 3rd generations cephalosporin in lower respiratory tract infections and pyelonephritis could be predicted.
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PMID:[Microbiological evaluation of differences between cephalosporins of second and third generations in general hospital]. 1274 20

The objective of this study was to elucidate the incidence and clinical features of renal dysfunction and urogenital system disorders in 956 patients with chronic obstructive lung disease (COLD) and/or coronary heart disease (CHD). COLD was diagnosed in 346 patients (group 1), COLD and CHD in 402 (group 2), CHD in 211 (group 3). The methods included X-ray studies (survey and excretory urography), functional diagnostics (ECG, Doppler cardiography, assessment of external respiration, abdominal, renal, and bladder ultrasound, measurements of residual urine, transrectal and transabdominal examination of prostate). The glomerular filtration rate was estimated using Cockcrofft-Gault and MDRD formulas and Rerberg- Tareev method, renal hemodynamics by duplex scanning of renal arteries. Inflammatory urogenital diseases were most frequently diagnosed in group 2 (chronic cystitis 83.8%, chronic pyelonephritis 73.9%). Diabetic nephropathy common in this group (25.4%) was related to the high prevalence of diabetes mellitus in these patients (37.8%) compared with 26.3 and 29.9% in groups 1 and 3 respectively. Ischemic renal disease occurred in every tenth patient of group 2 or much more frequently than in groups 1 and 3. This suggests additive COLD and CHD effect on the atherosclerotic process. The combination of these diseases was responsible for a large fraction of patients with chronic renal insufficiency in group 2 (45%). It is concluded that concomitant urogenital pathology in patients with COLD results in mutual aggravation of the clinical course of the two diseases and requires additional examination and obligatory medicamentous correction.
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PMID:[Urogenital pathology in patients with chronic obstructive lung disease and ischemic heart disease]. 1906 54

Cranberry containing products can protect against recurrent UTIs. The duration of treatment for uncomplicated pyelonephritis can be safely shortened to 7 days when using ciprofloxacin. Early surgical treatment for infective endocarditis in patients with large vegetations (> 10 mm) and valve dysfunction should be considered, even in the absence of urgent indications for surgery. Enterobacteriaceae with ESBL are less transmitted in hospital than in households. Tattoo ink-related mycobacterial infections are increasingly reported, even in Western Switzerland. Differentiating acute bacterial from viral rhinosinusitis on clinical criteria remains difficult. Antibiotic and non-antibiotic prevention of acute exacerbations of COPD is still a hot topic, we propose to discuss here.
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PMID:[Infectious diseases]. 2336 4

We report an interesting case involving an 81-year-old male patient who presented to our hospital with sepsis secondary to pyelonephritis and bacteremia. Blood cultures were positive for a Gram-negative bacillus, Burkholderia pseudomallei. His risk factors were diabetes, chronic obstructive pulmonary disease including travel to an endemic area. The patient received antibiotic therapy in accordance with the national guidelines. This is the first report of reactivation of latent melioidosis in the literature manifesting as pyelonephritis and bacteremia.
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PMID:Reactivation of latent melioidosis presenting with acute pyelonephritis and bacteremia. 2467 68