Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Asymptomatic bacteriuria in pregnant women has been linked to an increased incidence of pyelonephritis, preeclampsia, hypertension, intrauterine growth retardation and premature delivery. Pyelonephritis and cystitis require different antibiotics and dosages in pregnant patients. Renal calculi can be difficult to detect during pregnancy. Women with preexisting renal disease usually do well during pregnancy if renal function is preserved and hypertension is not present.
 ...
PMID:Renal disease and pregnancy. 265 May 4

Urinary tract infections (UTIs) can be difficult to diagnose positively in the pediatric patient. The patient with such an infection, however, is at risk for subsequent morbidity such as recurrence, renal damage and hypertension. Accurate diagnosis in the very young child may require multiple urine specimens involving repeating bag specimens, catheterization, or suprapubic aspiration. Septic children and those with pyelonephritis must be hospitalized. Children younger than 6 years old need follow-up with radiographic studies to rule out reflux and congenital anomalies. The clinician plays a significant role in detecting possible UTIs, and providing patient education and support.
 ...
PMID:Urinary tract infections in the pediatric patient. 266 95

8 patients, 2 men and 6 women, 42 to 67 years of age, with bilateral multiple cysts of the renal sinus are described. 3/6 patients had macroscopic hematuria, pyelonephritis, 5/8 patients were with arterial hypertension and 4/8 patients were with renal failure. All patients were examine by ultrasound once more after a greater diuresis was achieved in order to differentiate from hydronephrosis. The isotopic nephrographic curves were normal in 2/8 patients and were disturbed in the remaining 6 patients. Hydronephrotic type curves were not found. Urography was performed to 4 of the patients and in 2 of them the diagnosis was polycystosis and in the other 2 patients it was bilateral parapelvic cysts. Possible mistakes in the diagnosis of bilateral parapelvic cysts are discussed. The reported cases with superimposed pyelonephritis and renal failure point to the need of prophylactic medical examinations of such patients.
 ...
PMID:[Multiple bilateral parapelvic kidney cysts]. 269 27

Erythrocyte Na-Li countertransport was determined in 42 patients with essential hypertension (EH), 36 patients with hypertensive chronic diffuse glomerulonephritis, 47 patients with chronic pyelonephritis, 19 patients with renovascular hypertension and 9 patients with primary aldosteronism (PA). None of PA patients was treated with verospiron. Individual assessment of Na-Li exchange was made in 15 patients with nonspecific aorto-arteritis (NAA), untreated by steroid hormones, and in 2 glucocorticoid-treated NAA patients. Na-Li exchange parameters were compared before and after surgery in 7 patients with arterial hypertension (AH). Mean rate of Na-Li countertransport was nearly twice as high in EH patients as compared to the respective rate in patients with renal AH, whereas the difference in mean countertransport rates was not significant between EH and PA patients. Increased Na-Li exchange rate went down to normal values in a PA patient, while postoperative hydrocortizone treatment increased this rate in a patient with pheochromocytoma. In the remaining patients with symptomatic hypertensions (renovascular hypertension, pyelonephritic granular kidney, aortic coarctation, pheochromocytoma), Na-Li exchange remained unchanged after surgery. The rate of Na-Li exchange was increased in prednisolone-treated NAA patients, as compared to NAA patients receiving no glucocorticoids. The level of Na-Li exchange was stable over 9-18 months in AH patients with normal plasma aldosterone levels. No effects of obsidan, corinfar, clophelin, furosemide, hypothiazide and triampur on Na-Li exchange were identified.
 ...
PMID:[Sodium and lithium transport and steroid hormones of the adrenal glands]. 271 20

The activity of the kallikrein-kinin, prostaglandin and cyclase systems was assessed in 117 patients with chronic pyelonephritis with and without arterial hypertension. Pyelonephritis is shown to be associated with a dysfunction of the pressor-depressor mechanisms examined, featuring a depression of vasodepressor reactions. Patients with normal, increased and depressed humoral parameters could be found in each study group, the changes being particularly marked in patients with chronic pyelonephritis, combined with arterial hypertension.
 ...
PMID:[Function of the kallikrein-kinin and prostaglandin systems of the kidneys in patients with chronic pyelonephritis]. 271 90

Comparative evaluation of renal performance was conducted in 68 pregnant patients with nephropathies, stages I-II (first group) and in 53 pregnant females with nephropathy, stage III, associated with eclampsia (second group). Out of those 53 women, 28 patients suffered from combined gestosis in presence of chronic pyelonephritis and 25, in presence of chronic arterial hypertension. 20 females with normal pregnancy served as controls. In those with pregnancy complicated by nephropathies, stage I-II, the author revealed higher levels of blood plasma osmolality and its constituents in parallel with a significant decrease in concentration and clearance parameters of renal function. The latter resulted in statistically reliable increase in the urine concentration and clearance values. To avoid errors in the infusion therapy it was found necessary to carry out testing of renal functioning with the use of dosaged fluid load.
 ...
PMID:[Urinary concentration and clearance indicators in pregnant women with gestosis]. 274 58

Severe hypertension was diagnosed in a dog that initially was referred for evaluation of visual deficits and retinal hemorrhage and eventually was donated for medical treatment of hypertension. Initial blood pressure measured by direct methods was markedly high (systolic, 275 mm of Hg; diastolic, 170 mm of Hg). Measures of renal function were within normal limits, with the exception of hypotonic urine. A test protocol was designed to exclude possible secondary causes of hypertension; negative results of such tests allowed the diagnosis of essential hypertension. The consistency of the hypertension and its response to medical control were studied for 5 years. Blood pressure while the dog was untreated during those years was 240 +/- 24 mm of Hg (systolic) and 146 +/- 14 mm of Hg (diastolic). Plasma renin activity was within normal limits, and the response of the renin-angiotensin system to varied salt intake was normal. The most effective medications used to lower blood pressure were propranolol and captopril, both of which were more effective than salt restriction alone. Five years after the diagnosis of hypertension, the dog was euthanatized because of chronic renal failure secondary to pyelonephritis. Hypertension was less severe as the condition progressed into chronic renal failure. Complete necropsy did not reveal an obvious cause of the hypertension, and histopathologic changes were limited to the cardiovascular system, eyes, and kidneys.
 ...
PMID:Essential hypertension in a dog. 275

The characteristics of chronic pyelonephritis are studied in 37 patients out of a total of 53 patients with proved renal polycystosis. A group of 71 patients with chronic pyelonephritis selected at random are used as a control group. The frequency of chronic pyelonephritis among the patients with renal polycystosis is 69.8%. The difference between the mean age of the patients with renal polycystosis and chronic pyelonephritis and the patients with renal polycystosis without chronic pyelonephritis is 8.6 years. A significant difference is established between these two groups of patients concerning the frequency of symptomatic hypertension--89.2% for the patients with renal polycystosis and chronic pyelonephritis and 45% for the patients with uncomplicated renal polycystosis. A similar difference is established also for the renal failure--respectively 64.9% and 37.5%. The frequency of hypertension and chronic renal failure is lower in the control group of patients. 59% of the patients with renal polycystosis and chronic pyelonephritis have significant bacteriuria, E. coli and Proteus being the most frequently isolated bacteria but Pseudomonas shows the highest drug resistance. The isolated bacteria are most sensitive to nitroxoline and aminoglycoside antibiotics.
 ...
PMID:[Chronic pyelonephritis in polycystic kidney]. 277 65

The values of the Na-Li+ countertransport rate and the degree of monoclonal antibody binding with the erythrocyte membranes were compared in patients with different forms of arterial hypertension (AH) to identify combined pathology and the precursors of surgery effectiveness. Among the 27 examined AH patients 7 underwent surgery in accordance with the initial clinical diagnosis. The membrane tests helped to detect 3 patients with combined pathology: chronic pyelonephritis or chronic diffuse glomerulonephritis in combination with AH. Thus, the membrane tests were found to supplement each other in the assessment of surgery effectiveness and the perspectives for identification of combined pathology in patients with symptomatic AH of renal genesis.
 ...
PMID:[Detection of concomitant pathology in patients with arterial hypertension by structural and functional changes of erythrocyte membranes]. 277 59

150 patients dying from renal cell carcinoma are studied in order to reveal the background disease, incidence and character of the nephrosclerosis and the possible morphogenetic link between nephrosclerosis and carcinoma. Renal cell carcinoma is found to develop in 82.7% of cases in the kidneys with signs of nephrosclerosis. The diffuse nephrosclerosis developing in connection with the hypertension disease, atherosclerosis, diabetes mellitus, chronic pyelonephritis, nephrolithiasis is the most important. Proliferation of the canaliculi epithelium with the appearance of undifferentiated cells are regularly found in the nephrosclerotic areas. The disturbance of the epithelium differentiation is followed by the development of dysplasia the phenotypical variants of which are similar to those of renal cell carcinoma. Adenomas are found in 11.3% of cases of renal cell carcinoma which may originate from the adenomas developing against the background of nephrosclerosis.
 ...
PMID:[Background and precancerous processes in renal cell carcinoma]. 280 41


<< Previous 1 2 3 4 5 6 7 8 9 10