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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retrospective study of 1,100 consecutive renal transplantations done on 959 patients revealed postoperative pyelonephritis in 15 patients, 14 of whom were women. Sixteen of the 20 episodes of pyelonephritis were caused by Escherichia coli and only 4 episodes occurred within the first year after transplantation, thus revealing the crucial differentiation from a rejection episode. When the etiology of the original renal failure was pyelonephritis the incidence of pyelonephritis in the transplanted kidneys was high. This high incidence also was true for cases associated with post-transplantation urological complications. When the etiology of renal failure was diabetes or polycystic renal disease, or when urologic abnormalities pre-existed the incidence of pyelonephritis was low. No transplant or patient loss was caused by post-transplantation pyelonephritis, probably because of prompt, correct diagnosis and a low urological complication rate.
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PMID:Post-transplantation pyelonephritis: factors producing low patient and transplant morbidity. 698 76

Most physicians believe that diabetic individuals are predisposed to infections and that infection complicates the control of the diabetes. However, only bacteriuria can be documented to occur with increased frequency in diabetic compared with nondiabetic patients. Although most bacteriuric diabetic patients are asymptomatic, severe infections such as emphysematous pyelonephritis, papillary necrosis, perinephric abscess, and candida pyelonephritis may occur. Tuberculosis, once a proven threat to diabetic individuals, is a less serious problem now that effective screening and chemoprophylaxis programs have been initiated. Several unusual infections such as malignant external otitis, rhinocerebral mucormycosis, emphysematous pyelonephritis, and emphysematous cholecystitis occur also exclusively in diabetics. Foot infections are very important in diabetic patients; successful treatment requires accurate assessment of the extent and etiology of the infections and often involves surgery as well as broad antibiotic coverage. The important problem of infection in diabetic patients deserves careful evaluation. Questions such as do diabetic individuals have a higher incidence of infection, why are diabetic patients predisposed to infection, why is necrosis common in several of the infections, what is the course of asymptomatic bacteriuria, who do diabetic patients develop foot infections, and how should foot infections be prevented and treated should be topics of clinical investigation.
Diabetes Care
PMID:Infection and diabetes mellitus. 699 64

The low graft survival rate in black recipients (36 +/- 2% at 1 year) as compared with the graft survival rate in white recipients (48 +/- 1%) might be secondary to a higher incidence of vascular lesions, inducing hypertensive disease, in blacks than in whites. The relative frequency of malignant hypertension in black recipients was six times that of white recipients, and recipients with malignant hypertension had a significant lower graft survival rate (43 +/- 2%) than recipients with glomerulonephritis (54 +/- 1%). In addition, patients with vascular lesions (diabetes, malignant hypertension, and glomerulonephritis) showed significantly lower graft survival rates in black than in white recipients, in contrast to patients with primary tubular or interstitial lesions (polycystic kidneys and pyelonephritis), who showed similar graft survival rates in blacks and whites. Only a small fraction of this racial effect could be traced back to the higher incidence of Lewis-negative phenotypes in black recipients and a similar beneficial effect of transfusions, on graft survival, was observed in both black and white recipients. The effects of graft survival of age (6%), race (9%), and transfusions (18%) were significant in good (A) and poor (B) centers. No overlap between A and B centers was observed for any of these three parameters when analyzed separately. However, when the cumulative effects of these three risk parameters were analyzed together a partial overlap appeared, i.e., higher graft survival rates were observed in low-risk recipients that received transplants in B centers than in high-risk recipients that received transplants in A centers. Consequently, the selection of the recipient may play a role in the overall results of different transplantation units, leading to their classification into A or B centers, but cannot explain all of the differences between A and B centers.
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PMID:Influence of the original disease, race, and center on the outcome of kidney transplantation. 703 19

The course of pregnancy and treatment of diabetes mellitus during pregnancy were studied in 111 patients (119 pregnancies), who had fallen ill with diabetes mellitus before 5 (11 cases), at the age of 6-10 (39 cases), and at the age of 11-15 (61 cases). There were no patients with mild forms of the disease; 41.6% patients had diabetes mellitus of medium severity, and 58.4% patients grave forms of the disease. Diabetic retinopathy was observed in 47% patients, diabetic nephropathy in 13% patients, signs of acute and chronic pyelonephritis in 8.8% patients. Perinatal mortality in the group under observation was 13.4%. In the patients who had fallen ill with diabetes mellitus later it was 5.7%, and it was observed only in unstable and unsatisfactory compensation of diabetes mellitus. In women who had suffered diabetes since childhood and adolescence, hydramnion and toxemia of pregnancy were recorded in 40% cases.
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PMID:[The course of pregnancy and diabetes mellitus in pregnant women with a long-standing disease]. 706 49

Making use of immunoelectrophoretic method for semiquantitative determination, the fibrin/fibrinogen degradation products (FDP) were determined in urine and blood serum of 63 patients with diabetes mellitus with various vascular-degenerative and inflammatory complications in the kidneys as well as of 23 clinically healthy subjects. FDP presence in urine was found mainly in patients with diabetic nephropathy (in 32.6%). FDP in blood serum was found with significantly increased values in diabetic nephropathies (mean 14.9 mg/ml) and particularly in their advanced forms (mean 16.4 mg/ml), whereas in diabetics with chronic pyelonephritis, their content was increased in single cases (mean 1.9 mg/ml). A moderately manifested correlation of FDP in urine and serum with blood urea, serum creatinine and creatinine clearance was established as well as partly with protein quantity in urine and diastolic arterial pressure. The determination of FDP in urine and blood serum could serve as an additional sign in the differentiation of diabetic nephropathy and chronic pyelonephritis in diabetic patients.
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PMID:[Fibrin fibrinogen degradation products in the urine and blood in patients with diabetes mellitus and renal complications]. 716 12

There are two groups of diabetics under report, group I comprising 70 cases of retinopathia simplex, group II 100 cases of retinopathia proliferans in the centre. Retinopathy, showing as first sign of angiopathy, offers a comparatively good prognosis for the overall case of diabetes since, normally, neither retinopathia proliferans nor glomerulosclerosis are apt to develop. The same, in a higher degree, applies to cases of simple retinopathy fully devoloped and verified through ten years, at least: Retinopathy then shows stationary, in fact regressive development, the attending nephropathy generally expressing itself by the benign form of pyelonephritis and arteriolosclerosis renum rather than by glomerulosclerosis. All this in sharp contrast to proliferating retinopathy. Coronary sclerosis, peripheral and cerebral sclerosis and, to a limited extent, arterial hypertension stand independent of that; they attract attention by noteworthy independence.
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PMID:[The type of the diabetic retinopathy and the clinical picture of diabetes mellitus (author's transl)]. 744 11

Outcomes of radical surgery for prostatic adenoma have been analyzed for 426 patients divided into 3 groups. Group 1 included 160 patients subjected to urgent adenomectomy for acute urine retention, group 2 comprised 166 patients with severe intercurrent diseases subjected to one- and two-stage radical surgery, group 3 of 100 patients was free of intercurrent diseases. Urgent and delayed (within 72 hours and 5-10 days, respectively) radical adenomectomies are thought valid in management of acute urinary retention in patients with prostatic adenoma. Adequate preoperative preparation in deficient circulation, diabetes mellitus and other preexisting or concurrent diseases increased by 20-30% indications to the operation. Good outcomes were reported in 90%, 81.4% and 94% of patients from group 1, 2 and 3, respectively. 98.7% of 388 patients avoided suprapubic fistula and resumed natural urination. Only 1.3% of patients were discharged with cystostomy drainage of the bladder because of urethral stricture, urethrorectal fistula, renal failure and pyelonephritis. The differential approach provided good outcomes in 87.6% of seriously ill patients in overall hospital lethality 8.9%. The majority of the lethal outcomes resulted from purulent pyelonephritis (71%). The rest cases were due to acute affections of circulation, respiration and digestion.
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PMID:[Therapeutic tactics and results of prostatic adenomectomy in the presence of aggravating factors]. 747 27

Diabetes mellitus is a common multisystemic disease with serious effects on the genitourinary system. In the radiology literature, little attention has been paid to developing an integral approach to imaging of the genitourinary tract in diabetes. The long-term effects of diabetes on the genitourinary system include diabetic nephropathy, papillary necrosis, renal artery stenosis, diabetic cystopathy, and vas deferens calcification. Diabetes-associated urinary tract infections include renal and perirenal abscesses, gas-forming infections such as emphysematous pyelonephritis and emphysematous cystitis, fungal infections, and xanthogranulomatous pyelonephritis. Diabetes-associated genital infections include Fournier gangrene and postmenopausal tubo-ovarian abscess. In a diabetic with fever of unknown origin or in the event of a persistent infection in a diabetic with clinical deterioration despite use of antibiotics, radiologic studies can demonstrate the presence of genitourinary complications. Finally, radiologists should be aware of the risk of contrast material-induced nephropathy in diabetics.
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PMID:Imaging the effects of diabetes on the genitourinary system. 750 50

Basing on the results obtained in 380 patients, the efficacy of radical surgery of prostatic adenoma was studied in 3 groups of patients: group 1 (136 patients) underwent urgent adenomectomy because of acute urine retention; group 2 (153 patients) with severe concomitant diseases underwent one or two-stage adenomectomy; group 3 (92 patients) without clinically manifested somatic pathology. The author shows practical significance of urgent (within 72 hours) and delayed (within 5-10 days) radical adenomectomies in surgery of patients with acute urine retention. Long-term preoperative therapy of circulatory disorders and diabetes mellitus allowed performance of radical adenomectomy in additional 20-30% of group 2 patients. Positive outcomes were achieved in 88.2%, 80.4%, 93.4% of patients from groups 1, 2 and 3, respectively. Urination recovered in 98.5% of those operated on. Hospital lethality was 9.7%. Its cause was mainly purulent pyelonephritis (70.3%), the rest lethal outcomes occurred due to circulatory, respiratory and gastrointestinal diseases.
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PMID:[The characteristics of the surgical procedure in patients with the complications of prostatic adenoma and severe concomitant diseases]. 750 50

This study was carried out to determine the prevalence of hepatitis C virus (HCV) antibodies and the epidemiologic factors associated with HCV infection in patients with chronic renal failure before the onset of ESRD. Sex, age, type of renal disease, level of renal function, and history of blood transfusions and invasive procedures were analyzed in 226 patients with renal disease, compared with a population of 1,244 normal subjects and 124 patients with impaired immunity (patients having autoimmune diseases and receiving chemotherapy treatment). Eighteen seropositive patients with renal disease (prevalence, 7.9%) were found, which was significantly higher than the prevalence in the normal population (1.03% in blood donors, 0.98% in pregnant women; P < 0.001, chi 2). There was no significant association of sex, number of blood transfusions, or history of invasive procedures with the presence of HCV antibodies. The prevalence of HCV antibodies was higher (16.6%) in patients with glomerulonephritis compared with patients diagnosed with interstitial nephritis, pyelonephritis, nephrosclerosis, diabetes mellitus, polycystic kidney, and miscellaneous renal diseases (P < 0.01, chi 2). There was a higher prevalence of HCV antibodies in patients with creatinine clearance lower than 30 mL/min (13%) compared with patients with creatinine clearance higher than 30 mL/min (2.7%) (P < 0.01, chi 2). These data suggest that HCV infection may be associated with the pathogenesis of glomerulonephritis. Alternatively, glomerulonephritis or severe renal insufficiency may increase the likelihood of HCV infection.
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PMID:Epidemiology of hepatitis C virus infection in patients with renal disease. 752 63


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