Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034186 (pyelonephritis)
 6,144 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Computed tomography (CT) gives an excellent opportunity to revisit normal anatomy and to understand pathological aspects. Renal fascia alterations, on CT scans, are a sensitive sign of local lesion. While a thin renal fascia has no pathological significance, any thickening may be considered abnormal although nonspecific. It is found in pancreatitis as well as in cancer of the pancreas, in renal tumors as well as in pyelonephritis. It may persist as a scar. On the other hand, lack of fascial thickening allows us to rule out renal extension of a neighboring lesion or to decide that a renal mass is an ancient slowly-growing benign one.
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PMID:Radiological evaluation of the peri- and pararenal spaces by computed tomography. 664 Dec 57

Percutaneous nephrostomy can provide rapid relief of renal failure due to ureteral obstruction by contiguous spread of cervical malignancy. A series of 26 percutaneous nephrostomies placed in 14 patients with cervical cancer, using only local anesthesia and ultrasound or fluoroscopic guidance is presented. Twelve patients experienced no complications, one developed pyelonephritis which cleared rapidly with antibiotics, and one suffered a hematoma managed by surgical nephrostomy. Three of six previously untreated patients and one of eight patients with recurrent disease survived over a year. A single exenterated patient was stented when anuria developed after surgery to correct a conduit leak. This patient survives at 1.5 years with no evidence of recurrence. Indications for percutaneous nephrostomy, anticipated benefits, and the decision-making process involved in determining who to stent is reviewed.
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PMID:The role of percutaneous nephrostomy in gynecologic oncology. 665 81

Clinical studies on postoperative complications and prognosis were done on 27 patients who had undergone cystectomy at our hospital. Thirty one postoperative complications were seen in 16 patients. Early complications which developed within 3 months of operation were more frequent (25 cases). They included pyelonephritis (5 cases), wound infection (4 cases), pulmonary complications (2 cases), cardiovascular complications (2 cases), ileus (2 cases) and delayed ambulance (2 cases) in decreasing order of frequency. Complications related to urinary diversion were observed in 4 out of 6 late complications. Reoperation secondary to surgical complications were done in 6 cases. Four of the 6 reoperations were related to gastrointestinal complications, all of which would be fatal if left untreated. Postoperative followup period ranged from 3 weeks to 49 months with a mean period of 12.8 months. The present status of the patients is as follows: 16 patients alive, 10 patients dead and 1 patient lost to followup. So far we cannot draw a definite conclusion regarding the relationship between surgery and the prognosis of the patients because the followup period is too short in many patients. In our experience: 1) The fewest cancer deaths occurred in patients who had undergone radical surgery; 2) the largest percentage of living patients was seen in the group of patients who had undergone radical cystectomy; and, 3) almost all patients with low stage tumors are living more than 6 months after operation.
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PMID:[Postoperative complications and followup in cystectomy]. 667 24

A case of xanthogranulomatous pyelonephritis associated with 'small' renal carcinoma is presented. The urinary sediment showed atypical cells, suspect of malignancy. The renal neoplasm measured only 1.5 cm, had the typical papillary configuration of a 'small' renal carcinoma and was composed of atypical cells with finely granular cytoplasm and hyperchromatic nuclei. The xanthogranulomatous pyelonephritis was a primary lesion, spacially separate one from the other. The clinicopathological features of reported examples of coexistence of these diseases have been reviewed.
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PMID:Association of xanthogranulomatous pyelonephritis with small renal cell carcinoma. Case report and review of the literature. 669 91

The adenocarcinoid tumor is a potentially malignant neoplasm usually arising in the appendix. We describe a 55-year-old woman with a ureteroileal conduit in place for 12 years who suffered obstruction of the ileal segment of the conduit, with recurrent pyelonephritis and abdominal pain. Pathological examination of a segmentally resected portion of the conduit revealed a submucosal proliferation of nests of argentaffin/argyrophil cells and large, mucin-distended goblet cells. The patient showed no evidence of metastasis and has done well to date following excision. A discussion of neoplasms arising in the ureteroileal conduit is included.
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PMID:Adenocarcinoid tumor, goblet cell type, arising in a ureteroileal conduit: a case report. 670 35

In a 58-year-old man with the clinical and radiological signs of definite ankylosing spondylitis in its final stages, HLA B 27 positive, an onset of dermatomyositis was observed with characteristic clinical, histological, and pathological findings, and with high titers of ANA. It had been discovered years before that a gouty kidney with pyelonephritis accompanied the advanced ankylosing spondylitis. On the basis of these findings a triple association of etiologically different diseases could be diagnosed. After treatment with cortisone, allopurinol, and azathioprine appeared an acute and no longer controllable panmyelophthisis. That a malignant tumor could have caused the dermatomyositis was excluded by autopsy. Diagnostic questions concerning the gouty kidney as well as factors explaining the acute and deadly progress of a panmyelophthisis after the administration of a rather mild immunosuppressive agent are discussed.
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PMID:[Combination of ankylosing spondylitis with dermatomyositis and atypical gout (isolated gout kidney)]. 684 89

Experience with transcolonic Ureterosigmoidostomy (US) in 127 patients and colonic conduit (CC) in 152 patients is presented in detail. US proved to be highly satisfactory in children, in particular in bladder exstrophy (13% post-operative and 27% late complications, deterioration in 8% of all renal units), but gave poor results in adults. This was mainly due to the patient selection, as in this group preoperative damage to the upper urinary tract by pyelonephritis, obstruction, irradiation or previous surgery was frequent. Obviously these factors prohibit US. For the same reason US excludes adjunctive radiotherapy in cancer patients. Although employed in a higher renal risk group (signs of pyelonephritis in 34% and ureteral dilatation in 54% of the renal units in the preoperative IVP) CC with non-refluxing uretero-intestinal anastomoses reliably stabilized renal morphology (improvement of ureteral dilatation in 79%, over all deterioration 10% of all kidneys, mainly by progression of pyelonephritis established already before diversion). The low late complication rates of 21% in children and 31% in adults (with benign disease) compare favourably with the results reported in comparable series of ileal conduits.
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PMID:[Ureterosigmoidostomy and transcolonic cutaneous ureterostomy. Technical indications and results]. 716 47

Ceftezole (CTZ) was administered to 20 patients with hematopoietic malignancy complicated with infections. These patients consisted of 7 cases of AML, 2 ALL, 2 AMMoL, 1 APL, 1 blast crisis of CML, 2 HD, and 5 NHL. In 13 cases, sites of infection were determined and causative organisms were identified. In other 7 cases, sites of infection or causative organisms were unknown. In the former 13 cases, pneumonia was demonstrated in 6 patients, tonsillitis in 4 patients, pyelonephritis in 2 patients and sepsis in 1 patient. Klebsiella was separated from 5 patients as the causative organisms, E. coli from 2 patients, E. coli and Pseudomonas aeruginosa from 1 patient, Pseudomonas cepacia from 1 patient, Streptococcus viridans from 2 patients, Proteus from 1 patient and Torulopsis from 1 patient. Gram-negative rods were separated from 10 of the 13 cases (77%) as the causative organisms. CTZ was administered intravenously in dose from 4 g to 16 g per day combined with other antibiotics (AMK, GM, DKB, TOB, SBPC, CBPC, LC, ST). The response rate in 12 cases of acute leukemia and in 7 cases of malignant lymphoma was 58% and 43%, respectively. Infections occurred in 4 patients with less than 100 neutrophil per mm3 did never favorably responded even with CTZ.
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PMID:[Treatment of infection in the patients wih hematopoietic malignancy with ceftezole (Falomesin) (author's transl)]. 721 16

An immunohistochemical localization of ligandin was undertaken in formalin fixed and paraffin wax embedded human tissues using the indirect immunoperoxidase (PAP) method and a monospecific antiligandin serum raised in rabbits. A substance reacting with this antiligandin serum was distributed diffusely in normal liver and selectively in kidney, intestine, testis, ovary and adrenal cortex. Small changes in the distribution and intensity of the reaction product were found in inflammatory conditions such as hepatitis, cholestasis, pyelonephritis and renal allograft rejection. Tissues which normally appear to contain abundant ligandin produce, as a general rule, easily demonstrate amounts of antiligandin reacting substance in the tumors and hyperplasias which arise from them.
Cancer 1980 Feb
PMID:Immunohistological localization of ligandin in human tissues. 735 2

The need for urinary diversion is widespread for both benign and malignant disease and for patient of all ages. In the past 25 years, the urinary conduit concept of diversion has been the most widely practiced modality and has produced results that have been gratifying and acceptance, though not perfect. It is doubtful that a "perfect" solution to bladder substitution will ever be found, i.e., a solution without complications and without risk to long-term renal function. Of the various conduit operations, ileal conduit has been the one most widely employed. This procedure has produced a lower incidence of pyelonephritis and hyperchloremic acidosis than any method of diversion prior to 1950. However, it has been associated with significant complications and a threat to long-term renal function is now being recognized. Various efforts at improving these results are under way, aimed chiefly at avoiding the effects of ureteral anastomosis to irradiated bowel and at the development of non-refluxing ureteral anastomoses. Only time and careful study will determine the results of these efforts. We should adopt standardized parameters in the next 25 years in order to make meaningful comparisons possible. The parameters of greatest importance are a definition of complications clearly resulting from the diversion, a definition of pyelonephritis, and an agreement on a standard definition of "renal deterioration".
Cancer 1980 Jun 15
PMID:Current status of urinary diversion. 738 42


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