Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034069 (
pulmonary fibrosis
)
7,050
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
collagen
1360
Mol
720
Sep
423
cytokine
386
SMA
295
smooth muscle actin
249
fibronectin
201
TNF
155
IL-6
147
tumor necrosis factor
146
Smad2
130
superoxide dismutase
115
E-cadherin
110
TGF-beta
109
Smad3
105
vimentin
102
Hermansky-Pudlak syndrome
88
type I collagen
87
IL-13
83
connective tissue growth factor
83
myeloperoxidase
82
IL-4
79
alpha-smooth muscle actin
77
transforming growth factor-beta
77
matrix metalloproteinase
76
lipopolysaccharide
73
platelet-derived growth factor
73
She
68
COPD
66
p38
66
TNF-alpha
66
chemokine
66
catenin
66
endoplasmic reticulum
64
catalase
63
ERK
63
MMP-9
62
PDGF
60
MAPK
58
lactate dehydrogenase
57
surfactant protein C
54
p53
53
GSH
52
CD4
50
IL-10
49
IFN
49
IL-17
49
MRC
48
inducible nitric oxide synthase
46
interferon
45
MMP-2
44
Mal
44
caspase-3
44
BLM
44
SARS
43
IL-1
42
EPA
42
interleukin-6
42
plasminogen activator inhibitor-1
41
lymphoid
41
tyrosine kinase
40
AKT
39
thrombin
39
PI3K
39
IL-8
38
elastin
38
glutathione peroxidase
37
BAL
36
vascular endothelial growth factor
36
mTOR
36
IFN-gamma
35
JNK
35
ERK1
35
Fas
34
Cytokine
34
metalloproteinase
34
CTGF
33
interferon-gamma
32
c-Jun
31
HPS1
31
more...
Disease
pulmonary fibrosis
7050
idiopathic pulmonary fibrosis
1193
lung disease
730
cancer
509
emphysema
377
interstitial lung disease
369
pneumonia
350
interstitial pneumonia
349
chronic obstructive pulmonary disease
341
asthma
313
pulmonary hypertension
305
PSS
301
lung cancer
296
respiratory failure
259
sarcoidosis
256
tumor
217
scleroderma
159
rheumatoid arthritis
158
silicosis
153
hypertension
143
bronchiectasis
141
cystic fibrosis
122
asbestosis
108
bronchiolitis
106
hypersensitivity pneumonitis
102
Hermansky-Pudlak syndrome
98
arthritis
91
pneumoconiosis
87
vasculitis
83
systemic lupus erythematosus
81
Raynaud's phenomenon
80
pulmonary edema
77
diabetes
76
adult respiratory distress syndrome
74
respiratory disease
70
carcinoma
66
COPD
66
tuberculosis
63
mesothelioma
62
connective tissue disease
62
heart failure
60
SARS
58
cirrhosis
57
pneumothorax
56
GSH
52
dyskeratosis congenita
51
dermatomyositis
49
colitis
48
chronic bronchitis
47
cor pulmonale
47
atherosclerosis
46
bronchopulmonary dysplasia
46
BLM
45
liver fibrosis
44
eosinophilia
44
metastases
43
virus infection
42
sepsis
42
polymyositis
40
sepsis
40
cardiovascular disease
39
autoimmune disease
39
renal failure
38
breast cancer
37
influenza
37
adenocarcinoma
36
non-small cell lung cancer
36
myositis
35
Thorax
35
infectious diseases
33
bronchitis
33
vascular disease
33
Hodgkin's disease
33
Langerhans cell histiocytosis
33
gastroesophageal reflux disease
32
bronchitis
32
sclerodactyly
31
pulmonary tuberculosis
31
aplastic anemia
31
lymphadenopathy
30
more...
Symptom
dyspnea
251
respiratory distress
166
cough
138
collapse
45
hyperoxia
42
exertional dyspnea
41
hemoptysis
39
anesthesia
38
shortness of breath
38
pain
32
fatigue
31
vomiting
26
weakness
25
diarrhea
23
nausea
20
clubbing
19
arthralgia
18
anorexia
18
chest pain
17
chronic cough
17
wheezing
16
erythema
15
nausea and vomiting
14
tachypnea
13
rales
12
headache
11
myalgia
10
cyanosis
10
chills
9
productive cough
9
cachexia
8
hypercapnia
8
hepatosplenomegaly
7
asthenia
7
Ill
7
pleuritic chest pain
6
analgesia
6
photophobia
6
tremor
6
Respiratory symptoms
6
hypocapnia
5
abdominal pain
5
discomfort
5
night sweats
5
discomfort
5
dry eye
5
thinning
5
regurgitation
4
non-productive cough
4
dysarthria
4
angina
4
seizures
4
exhaustion
4
livedo
4
dry skin
3
heartburn
3
numbness
3
abdominal discomfort
2
overweight
2
lethargy
2
bone pain
2
oliguria
2
hypoproteinemia
2
breath holding
2
starvation
2
hepatomegaly
2
low back pain
2
hoarseness
2
chest tightness
2
constipation
2
syncope
2
postnasal drip
2
fever of unknown origin
2
Physical findings
2
insomnia
2
bradykinesia
2
rhinorrhea
2
heel pain
2
vertigo
2
spasm
1
more...
Drug
Dermatol
56
MRC
48
BLM
46
Pirfenidone
43
IFN-gamma
36
Cardiovasc
32
Silica
32
lysine
26
ROS
25
CSF
19
vitamin E
18
Monit
17
Asthma
16
CTX
13
niacin
10
TiO2
10
Leaf
9
IL-2
9
uPA
7
ascorbate
7
Prednisolone
6
ETA
6
Emodin
6
Bleomycins
6
Emodin
6
Gel
6
Mutagen
5
Indomethacin
5
Vitamin E
5
ADM
5
Captopril
5
VCR
4
IL-11
4
Tacrolimus
4
Gefitinib
4
Activin
4
EE2
4
Gelatin
4
nitroglycerin
4
Itraconazole
4
SiO2
4
Paraffin
4
Sivelestat
4
Oxaliplatin
4
Prednisone
3
KGF
3
Talc
3
Fructose
3
Infliximab
3
caffeine
3
Histamine
3
Glycyrrhiza
3
CCL
3
ENT
3
Adriamycin
3
Urokinase
3
Everolimus
3
Infliximab
3
Methylprednisolone
3
citric acid
3
Gleevec
3
VCR
3
Dronedarone
2
Senicapoc
2
Heme
2
Angiotensin II
2
Artesunate
2
Dial
2
Bayer
2
Dasatinib
2
Blenoxane
2
Helium
2
Vinorelbine
2
PDGF B-chain
2
Cangrelor
2
DEX
2
Imatinib
2
Erlotinib
2
Fluorescein
2
Simvastatin
2
more...
Enzyme
mitogen-activated protein kinase
157
superoxide dismutase
136
ERK
98
peroxidase
96
catalase
64
collagenase
63
lactate dehydrogenase
61
focal adhesion kinase
55
ACE
47
protein kinase
40
luciferase
38
thrombin
37
glutathione peroxidase
37
BAL
36
urokinase-type plasminogen activator
31
reverse transcriptase
29
caspase-3
28
prolyl hydroxylase
27
elastase
24
renin
23
type III procollagen
21
protein kinase C
20
NADPH oxidase
20
MMP
19
MEK
18
NADPH oxidase
18
phosphodiesterase
16
lysyl oxidase
15
arginase
14
plasmin
14
matrix metalloproteinase 9
14
neutrophil elastase
13
trypsin
13
alkaline phosphatase
13
RNA polymerase
13
MIP
13
APC
13
proteasome
12
SPC
12
chymase
11
RNase
11
glutathione reductase
11
RNase
11
matrix metalloproteinase 2
10
caspase-1
10
ACS
10
glutathione S-transferase
10
topoisomerase
10
aspartate aminotransferase
10
lysozyme
9
NO synthase
9
caspase-9
9
topoisomerase
9
acid phosphatase
9
phosphatidylinositol 3-kinase
9
alanine aminotransferase
9
pepsin
8
chitinase
8
GSK
7
creatine kinase
7
caspase-8
7
interstitial collagenase
7
PARP
7
NQO1
7
beta-glucuronidase
6
xanthine oxidase
6
transcriptase
6
neuraminidase
6
MMP-3
6
phospholipase C
6
phospholipase A2
6
macrophage elastase
6
hyaluronidase
5
tyrosinase
5
thioredoxin reductase
5
PAH
5
tryptase
5
cathepsin D
5
phosphoinositide 3-kinase
5
NOS
5
more...
Compound
Dec
462
oxygen
445
Clin
421
BLM
296
DNA
292
TNF
155
CO2
115
water
80
Collagen
74
phosphate
72
nitric oxide
69
Paraquat
68
Paraquat
66
iron
64
calcium
63
Asbestos
56
GSH
52
GSH
52
silicon
52
proline
51
Amiodarone
49
acetate
46
sulfate
45
cysteine
41
tyrosine
38
BAL
37
His
35
sodium
35
N-acetylcysteine
34
MTT
30
Hydroxyproline
29
lysine
29
hydrogen
29
Cardiol
26
arginine
26
MDA
26
nitrogen
26
ASA
26
prostacyclin
25
PGE
24
titanium
24
creatinine
24
cobalt
24
potassium
23
BCNU
23
PGE2
23
glucose
23
ATP
22
THP
21
THP
21
guanidine
21
nickel
20
ANCA
20
Hematoxylin
19
serine
19
zinc
19
copper
18
Methotrexate
18
H2O2
17
SiO2
17
cAMP
17
urea
16
salt
15
tungsten
15
aluminum
15
Curcumin
14
Angiotensin II
14
NAD
14
dUTP
14
CTX
13
Thrombin
13
MEK
13
H2S
13
NADPH
12
Vimentin
12
NADPH
12
threonine
12
ethanol
12
Adenosine
11
leucine
11
more...