Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034067 (
emphysema
)
11,506
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
elastase 2B
11.4
IREB2 protein
11.4
ANKRD18A
10.4
Alpha-1 antitrypsin
10.3
alpha-1 globin
10.1
LTA4H protein
9.8
MFAP3
9.8
ZNHIT6
9.8
TACC2 protein
9.8
MME protein
9.8
Metalloelastase
9.6
COBP
9.6
p0071 protein
9.4
metalloelastase
9.0
Alpha-1-antitrypsin
9.0
Zinc finger E-box binding homeobox 2
8.8
ARHGAP28
8.8
ARCP
8.8
matrix metalloproteinase 12
8.8
MMP12
8.7
FBLN5
8.6
alpha-1 antitrypsin
8.5
RAG1 mRNA
8.4
CCDC103
8.4
ASRGL1
8.4
FBLN4
8.3
SERPINE2
8.3
FAM13A
8.3
GPR116
8.3
NADPH oxidase organizer 1
8.3
retinoic acid early transcript 1
8.3
CALM/AF10 fusion
8.3
MMP-12
8.1
ARCL
8.1
PS21
8.1
neutrophil elastase
8.0
MFAP1
8.0
UBCH7
8.0
LPHN2
8.0
anti-elastase
8.0
LTBP-4
7.9
elastase inhibitor
7.9
alpha 1-antitrypsin
7.9
CTDP1
7.8
NPNT
7.8
RAB4B
7.8
bomapin
7.8
SVIP
7.8
DANCE
7.8
alpha-1-antitrypsin
7.8
Surfactant protein D
7.7
COPD
7.7
AAT
7.7
PCBP3
7.6
ROR gamma
7.6
IL13RA1
7.5
Pancreatic elastase
7.5
MFAP5
7.5
ORC6
7.5
NINJ2
7.4
Apoptosis inhibitor
7.3
x25
7.3
Histone deacetylase 2
7.3
BICD1
7.3
fibulin-4
7.3
FEV
7.3
ABHD2
7.3
Retinol dehydrogenase 12
7.3
V75
7.2
HDAC2 protein
7.1
NPT2
7.1
CHRNA
7.1
ORC4
7.1
HHIP
7.0
Tissue inhibitor of metalloproteinase 1
7.0
CL-6
7.0
elastin precursor
7.0
FNIP2
7.0
HS6ST2
7.0
MFAP4
7.0
more...
Disease
asthma, exogenous
11.4
Instantaneous clearance
11.4
Esophageal tear
11.4
emphysema
11.4
Linear atelectasis
11.4
Orbital emphysema
11.3
Giant bullous emphysema
11.1
Paraseptal emphysema
11.1
Centrilobular emphysema
11.1
Panlobular emphysema
11.0
Vanishing lung
10.9
Tracheal perforation
10.8
Bronchiolectasis
10.8
Bullous emphysema
10.7
Interstitial pulmonary emphysema
10.4
Pulmonary pneumatocele
10.4
Tracheal rupture
10.2
Chronic pulmonary histoplasmosis
10.1
Chronic obstructive bronchitis
10.1
Respiratory bronchiolitis-associated interstitial lung disease
10.0
AAT deficiency
9.9
smokers lung
9.8
Gas bubble disease
9.8
Old tuberculosis
9.8
Pharyngeal perforation
9.8
Bronchocutaneous fistula
9.8
Plate-like atelectasis
9.8
Factitious lymphedema
9.8
Interstitial emphysema
9.8
Emphysematous gastritis
9.8
small airways disease
9.5
Traumatic reticuloperitonitis
9.4
Obstructive bronchitis
9.4
Diffuse pulmonary fibrosis
9.4
Chronic respiratory failure
9.4
Clinical pneumonia
9.4
Open pneumothorax
9.4
Bullous lung disease
9.4
pneumopericardium
9.4
Chronic Airflow Obstruction
9.3
Chronic mucus hypersecretion
9.3
Acute exacerbation of chronic bronchitis
9.1
Gastric erosion
9.1
Generalized atherosclerosis
9.1
Periapical abscesses
9.1
FENIB
9.1
Obstructive emphysema
9.1
chronic bronchitis
8.9
Pulmonary Disorder
8.8
Bronchial infection
8.8
Acute anaphylaxis
8.8
Traction bronchiectasis
8.8
Severe chronic obstructive pulmonary disease
8.8
Congenital cutis laxa
8.7
uremic pneumonitis
8.6
Chronic lower respiratory diseases
8.6
sinus problem
8.6
Boerhaave's syndrome
8.5
vertiginous syndrome
8.4
Postoperative atelectasis
8.4
Laryngeal papilloma
8.4
tension pneumothorax
8.4
chronic bronchiolitis
8.3
14q deletion syndrome
8.3
congestive atelectasis
8.3
Moderate depression
8.3
Type III reaction
8.3
Secondary tuberculosis
8.3
pneumothorax
8.3
Hypocomplementemic urticarial vasculitis
8.2
Auto-PEEP
8.2
anthracosis
8.1
unable to stop smoking
8.1
CLE
8.1
Elastolysis
8.0
Acquired cutis laxa
8.0
Chronic rheumatic heart disease
8.0
Biventricular hypertrophy
8.0
Esophageal rupture
8.0
Rectal perforation
7.8
more...
Symptom
Bronchial breathing
9.4
Blotchy
9.0
Lung hyperinflation
8.9
Air trapping
8.8
Rhonchi
8.4
feeling of choking
8.1
Lung hernia
7.7
swollen scrotum
7.4
Diaphragmatic weakness
7.2
Thoracic pain
7.1
Hoover's sign
6.9
Portal venous gas
6.8
vasovagal attacks
6.8
dyspnea
6.2
labored breathing
6.0
productive cough
5.8
respiratory distress
5.8
shortness of breath
5.7
Platypnea
5.7
nocturnal cough
5.6
hemoptysis
5.6
exertional dyspnea
5.6
retching
5.5
itchy nose
5.5
wheezing
5.5
Respiratory symptoms
5.4
chest tightness
5.3
chronic cough
5.3
rales
5.3
diastolic murmurs
5.2
pleuritic chest pain
5.2
clubbing
5.2
stridor
5.2
hypercapnia
5.2
cyanosis
5.1
aphonia
5.1
sneezing
5.1
prominent nose
5.1
frequent urination
5.0
hoarseness
5.0
cough
5.0
tachypnea
4.9
non-productive cough
4.9
catarrh
4.8
sighing
4.8
persistent cough
4.8
Nasal symptoms
4.7
abnormal breathing
4.7
cardiovascular impairment
4.7
monoplegia
4.7
Physical findings
4.6
chest pain
4.6
Exercise intolerance
4.6
bigeminal
4.4
sore throat
4.4
photopsia
4.4
Postoperative nausea and vomiting
4.4
thigh pain
4.4
pneumaturia
4.3
neck pain
4.3
breath holding
4.3
voice change
4.2
iliac fossa pain
4.1
Regurgitation
3.9
eye pain
3.9
nasal discharge
3.8
collapse
3.8
bradypnea
3.8
Opposition
3.8
emaciation
3.7
epigastric pain
3.7
inanition
3.6
orthopnea
3.6
hyperoxia
3.5
hyperemesis gravidarum
3.3
vomiting
3.2
thirsty
3.1
otalgia
3.1
drooling
3.0
testicular pain
3.0
more...
Drug
Colfosceril palmitate
11.4
Prolastin
9.8
Dried yeast
9.4
Seratrodast
8.1
Ferric oxide
7.4
Citrus unshiu peel
7.3
Spiriva
7.3
Terbutaline sulfate
7.2
Frova
7.0
Oxybuprocaine
6.8
Arachidonic Acid
6.8
Bisolvon
6.7
Survanta
6.5
Panipenem
6.4
Cilomilast
6.0
Talc
6.0
Atrovent
5.8
Berotec
5.8
Ipratropium bromide
5.7
Frovatriptan
5.7
Papain
5.6
TPV
5.6
PAPM/BP
5.5
Cordarone
5.5
Lasalocid
5.5
ATV
5.5
Roflumilast
5.4
Roflumilast
5.4
Cordarone
5.3
Pimobendan
5.3
Buscopan
5.2
Pirfenidone
5.1
Bricanyl
5.1
Ceftibuten
5.1
Sodium hypochlorite
5.0
Domin
5.0
Polydioxanone
4.9
SF6
4.7
Ritalin
4.6
CA-074
4.6
Trapidil
4.6
Helium
4.5
CDX
4.4
DPE
4.3
Molsidomine
4.2
FLM
4.2
CPZ
4.1
Beta-2
4.1
CDX
4.0
SBT
3.8
Rolipram
3.7
Amrinone
3.6
Fenoterol
3.5
Magnevist
3.5
MRC
3.5
PFT
3.5
Iopamidol
3.5
Theophylline
3.5
Sinemet
3.4
Prednisolone
3.2
IPD
3.2
Vena
3.1
Vena
3.1
Monensin
3.1
CCL
3.1
Dexon
3.1
Colombo
3.1
Salbutamol
3.0
Gelatin
3.0
Posaconazole
2.9
Gelfoam
2.9
BCG vaccine
2.9
Xanthium
2.7
Asthma
2.7
Hyaluronidase
2.6
CVA
2.5
Hyaluronidase
2.5
Prednisone
2.4
Piperacillin
2.4
Fraction
2.4
more...
Enzyme
macrophage elastase
9.5
neutrophil elastase
7.9
elastase
7.8
matrix metalloproteinase 10
6.3
cathepsin G
5.7
cathepsin S
5.5
beta-D-fucosidase
5.4
proteinase-3
5.3
lysyl oxidase
5.3
papain
5.3
matrix metalloproteinase 14
5.0
neutrophil collagenase
4.9
N-acetylglucosaminyltransferase III
4.8
microsomal epoxide hydrolase
4.8
BAL
4.7
interstitial collagenase
4.7
ceramide kinase
4.7
DAP II
4.7
methionine sulfoxide reductase
4.5
PPH
4.5
CYP7B1
4.5
neutral sphingomyelinase
4.4
CAO
4.0
violaxanthin de-epoxidase
4.0
cathepsin L
3.9
phosphatidylinositol-4,5-bisphosphate 3-kinase
3.8
matrix metalloproteinase 9
3.8
sphingomyelin synthase
3.6
NCP
3.5
meprin
3.3
LTA4 hydrolase
3.2
MMP
3.2
collagenase
3.1
aspartate aminotransferase
3.1
ceramidase
3.0
mu-calpain
3.0
FPS
3.0
gamma-glutamylcysteine synthetase
3.0
cathepsin H
2.9
SPC
2.9
matriptase
2.9
cruzipain
2.7
12-lipoxygenase
2.7
PTR
2.7
CPN
2.7
soluble epoxide hydrolase
2.6
MIP
2.6
lactonase
2.6
cathepsin K
2.6
caspase-6
2.5
MMP-3
2.5
caspase-6
2.5
matriptase
2.5
trypsin
2.3
cathepsin B
2.2
prolyl hydroxylase
2.2
xanthine dehydrogenase
2.2
tissue kallikrein
2.1
15-hydroxyprostaglandin dehydrogenase
2.1
factor C
2.1
SMP
2.0
heme oxygenase
2.0
chymotrypsin
1.9
sphingosine kinase
1.9
matrix metalloproteinase 2
1.8
MCS
1.8
prolyl endopeptidase
1.8
caspase-3
1.8
beta-glucuronidase
1.7
kallikrein
1.7
p100
1.6
plasmin
1.6
tryptase
1.6
MEKK1
1.6
TdT
1.5
mannanase
1.5
phosphodiesterase
1.5
ceruloplasmin
1.4
NADPH oxidase
1.4
NADPH oxidase
1.4
more...
Compound
O-phosphonothreonine
11.4
C8H9NO3
9.4
11-Tricosene
9.4
PIMM
8.6
Desmosine
8.3
Noleptan
8.0
AAT
7.4
Dionosil
7.3
3-methylindole
7.2
Nitroethane
7.1
Ipratropium
7.1
1,2-dithiane
6.8
Pirbuterol
6.7
Sodium hydrosulfide
6.6
Elastin
6.5
Nedocromil
6.5
Fluticasone
6.2
Fluticasone
6.0
ELA
5.7
ELA
5.7
4H-pyrido[1,2-a]pyrimidin-4-one
5.5
Isoproturon
5.4
Zinc chloride
5.3
Cefmetazole
5.1
1,2-dithiolane
5.0
FMI
5.0
Heptachlor
4.9
2-methylbutanal
4.9
Triolein
4.9
Prone
4.8
2,5-dichlorophenol
4.8
8-hydroxyguanosine
4.8
Ritalin
4.8
Diallyl disulfide
4.8
Diallyl disulfide
4.8
HSM
4.7
Aminophylline
4.7
1-Nitropyrene
4.7
Sulfinpyrazone
4.6
Glucosylceramide
4.6
Tazobactam
4.5
1,3-propanediamine
4.5
Tolazoline
4.5
Ceftizoxime
4.5
Xenon
4.4
hexuronic acid
4.4
hexuronic acid
4.3
hexuronic acid
4.3
hexuronic acid
4.3
S-methylcysteine
4.3
Florid
4.3
BAL
4.3
TEP
4.2
SHS
4.2
benzenesulfonyl fluoride
4.2
MME
4.0
Gliotoxin
3.9
CPZ
3.9
Elan
3.9
DSE
3.9
Sudan IV
3.8
Sulbactam
3.8
Oridonin
3.7
Theophylline
3.7
1,3-Butadiene
3.7
Farnesol
3.7
CdCl2
3.7
Cetirizine
3.7
Sarcosine
3.6
Triamcinolone acetonide
3.6
Elan
3.6
Isoflavone
3.6
CO2
3.6
APN
3.6
Formoterol
3.5
Matrine
3.5
Matrine
3.5
Matrine
3.5
Mesna
3.5
Heparan sulfate
3.5
more...